ASO Author Reflections: The Number of Involved Structures is a Promising Prognostic Factor in Thymic Epithelial Tumors.
Chiappetta M, Lococo F, Sassorossi C, Aigner C, Ploenes T, Van Raemdonck D, Vanluyten C, Van Schil P, Agrafiotis A, Guerrera F, Lyberis P, Casiraghi M, Spiaggiari L, Zisis C, Magou C, Moser B, Bauer J, Thomas PA, Brioude G, Passani S, Zsanto Z, Sperduti I, Margaritora S.Ann Surg Oncol. 2024 Apr 20. doi: 10.1245/s10434-024-15285-x
Computed Tomography-Based Body Composition is Related to Perioperative Morbidity in Older Lung Transplant Recipients. Kifjak D, Prosch H, Schwarz S, Jaksch P, Weber M, Hoetzenecker K, Schweiger T.Thorac Cardiovasc Surg. 2024 Apr 16. doi: 10.1055/s-0044-1782683
In-depth analysis of pre- and post-operative functional outcome parameters in patients receiving laryngotracheal surgery. Evermann M, Roesner I, Denk-Linnert DM, Klepetko W, Schweiger T, Hoetzenecker K.Eur J Cardiothorac Surg. 2024 Apr 19:ezae171
Prognostic factors of recurrence and disease-free survival in radically resected pulmonary carcinoids: a real-world analysis. Spils M, Klikovits T, Krenbek D, Hochmair MJ, Jankovic I, Schulte L, Krajc T, Benej M, Getman V, Navarrete JR, Akan A, Mueller MR, Aigner C, Watzka SB.J Thorac Dis. 2024 Mar 29;16(3):1911-1922
Alternative venous access sites for dual-lumen extracorporeal membrane oxygenation cannulation. Schoeberl AK, Staudacher D, Kawashima M, Fischer C, Cypel M, Buchtele N, Staudinger T, Aigner C, Hoetzenecker K, Schweiger T.Interdiscip Cardiovasc Thorac Surg. 2024 Apr 11:ivae060
Long-Term Survival in Patients with Oligometastatic Non-Small Cell Lung Cancer by a Multimodality Treatment-Comparison with Stage III Disease. Guberina M, Pöttgen C, Guberina N, Hoffmann C, Wiesweg M, Richlitzki C, Metzenmacher M, Aigner C, Bölükbas S, Gauler T, Eberhardt WEE, Forsting M, Herrmann K, Theegarten D, Darwiche K, Jendrossek V, Stuschke M, Schuler M.Cancers (Basel). 2024 Mar 17;16(6):1174
The Prognostic Role of the Number of Involved Structures in Thymic Epithelial Tumors: Results from the ESTS Database.
Chiappetta M, Lococo F, Sassorossi C, Aigner C, Ploenes T, Van Raemdonck D, Vanluyten C, Van Schil P, Agrafiotis AC, Guerrera F, Lyberis P, Casiraghi M, Spiaggiari L, Zisis C, Magou C, Moser B, Bauer J, Thomas PA, Brioude G, Passani S, Zsanto Z, Sperduti I, Margaritora S.Ann Surg Oncol. 2024 Mar 26. doi: 10.1245/s10434-024-15194-z. Online ahead of print.PMID: 38530530
Identification of FasL as a crucial host factor driving COVID-19 pathology and lethality.
Albert MC, Uranga-Murillo I, Arias M, De Miguel D, Peña N, Montinaro A, Varanda AB, Theobald SJ, Areso I, Saggau J, Koch M, Liccardi G, Peltzer N, Rybniker J, Hurtado-Guerrero R, Merino P, Monzón M, Badiola JJ, Reindl-Schwaighofer R, Sanz-Pamplona R, Cebollada-Solanas A, Megyesfalvi Z, Dome B, Secrier M, Hartmann B, Bergmann M, Pardo J, Walczak H.Cell Death Differ. 2024 Mar 21. doi: 10.1038/s41418-024-01278-6. Online ahead of print.PMID: 38514848
Resectable non-stage IV nonsmall cell lung cancer: the surgical perspective.
Aigner C, Batirel H, Huber RM, Jones DR, Sihoe ADL, Štupnik T, Brunelli A.Eur Respir Rev. 2024 Mar 20;33(171):230195. doi: 10.1183/16000617.0195-2023. Print 2024 Jan 31.PMID: 38508666
Evolutionary trajectories of small cell lung cancer under therapy.
George J, Maas L, Abedpour N, Cartolano M, Kaiser L, Fischer RN, Scheel AH, Weber JP, Hellmich M, Bosco G, Volz C, Mueller C, Dahmen I, John F, Alves CP, Werr L, Panse JP, Kirschner M, Engel-Riedel W, Jürgens J, Stoelben E, Brockmann M, Grau S, Sebastian M, Stratmann JA, Kern J, Hummel HD, Hegedüs B, Schuler M, Plönes T, Aigner C, Elter T, Toepelt K, Ko YD, Kurz S, Grohé C, Serke M, Höpker K, Hagmeyer L, Doerr F, Hekmath K, Strapatsas J, Kambartel KO, Chakupurakal G, Busch A, Bauernfeind FG, Griesinger F, Luers A, Dirks W, Wiewrodt R, Luecke A, Rodermann E, Diel A, Hagen V, Severin K, Ullrich RT, Reinhardt HC, Quaas A, Bogus M, Courts C, Nürnberg P, Becker K, Achter V, Büttner R, Wolf J, Peifer M, Thomas RK.Nature. 2024 Mar 13. doi: 10.1038/s41586-024-07177-7. Online ahead of print.PMID: 38480884
Reply to Spiliopoulos et al.
Traxler D, Ankersmit HJ.Eur J Cardiothorac Surg. 2024 Mar 1;65(3):ezae072. doi: 10.1093/ejcts/ezae072.PMID: 38478403
The ESTS-AIR database-initial results of a multi-institutional database on airway surgery.
Schweiger T, Evermann M, Rendina E, Maurizi G, Venuta F, Aigner C, Slama A, Collaud S, Verhagen A, Timman S, Bibas B, Cardoso P, Passani S, Salati M, Opitz I, Szanto Z, Hoetzenecker K.Eur J Cardiothorac Surg. 2024 Mar 9:ezae084. doi: 10.1093/ejcts/ezae084. Online ahead of print.PMID: 38460190
The Proteome of Extracellular Vesicles Released from Pulmonary Microvascular Endothelium Reveals Impact of Oxygen Conditions on Biotrauma.
Schaubmayr W, Hochreiter B, Hunyadi-Gulyas E, Riegler L, Schmidt K, Tiboldi A, Moser B, Klein KU, Krenn K, Scharbert G, Mohr T, Schmid JA, Spittler A, Tretter V.Int J Mol Sci. 2024 Feb 19;25(4):2415. doi: 10.3390/ijms25042415.PMID: 38397093
Small cells - big issues: biological implications and preclinical advancements in small cell lung cancer.
Solta A, Ernhofer B, Boettiger K, Megyesfalvi Z, Heeke S, Hoda MA, Lang C, Aigner C, Hirsch FR, Schelch K, Döme B.Mol Cancer. 2024 Feb 24;23(1):41. doi: 10.1186/s12943-024-01953-9.PMID: 38395864
Compartment-specific remodeling patterns in end-stage chronic obstructive pulmonary disease with and without severe pulmonary hypertension.
Zeder K, Marsh LM, Avian A, Brcic L, Birnhuber A, Douschan P, Foris V, Sassmann T, Hoetzenecker K, Boehm PM, Kwapiszewska G, Olschewski A, Olschewski H, Kovacs G.J Heart Lung Transplant. 2024 Feb 19:S1053-2498(24)01087-8. doi: 10.1016/j.healun.2024.02.1044. Online ahead of print.PMID: 38382583
C-Myc protein expression indicates unfavorable clinical outcome in surgically resected small cell lung cancer.
Lang C, Megyesfalvi Z, Lantos A, Oberndorfer F, Hoda MA, Solta A, Ferencz B, Fillinger J, Solyom-Tisza A, Querner AS, Egger F, Boettiger K, Klikovits T, Timelthaler G, Renyi-Vamos F, Aigner C, Hoetzenecker K, Laszlo V, Schelch K, Dome B.World J Surg Oncol. 2024 Feb 19;22(1):57. doi: 10.1186/s12957-024-03315-7.PMID: 38369463
ESR Bridges: imaging and treatment of lung cancer-a multidisciplinary view.
Beer L, Hochmair M, Heilmann M, Hoda MA.Eur Radiol. 2024 Feb 15. doi: 10.1007/s00330-023-10523-4. Online ahead of print.PMID: 38355985
The Advent of Semi-Elective Lung Transplantation-Prolonged Static Cold Storage at 10°C.
Hoetzenecker K, Benazzo A, Schwarz S, Keshavjee S, Cypel M.Transpl Int. 2024 Jan 22;37:12310. doi: 10.3389/ti.2024.12310. eCollection 2024.PMID: 38317690
A European Multi-Center Analysis of Extracorporeal Photopheresis as Therapy for Chronic Lung Allograft Dysfunction.
Benazzo A, Bagnera C, Ius F, Del Fante C, Gottlieb J, Hoetzenecker K, Meloni F, Jaksch P, Greer M.Transpl Int. 2024 Jan 12;36:11551. doi: 10.3389/ti.2023.11551. PMID: 38282747
Coronavirus Receptor Expression Profiles in Human Mast Cells, Basophils, and Eosinophils.
Degenfeld-Schonburg L, Sadovnik I, Smiljkovic D, Peter B, Stefanzl G, Gstoettner C, Jaksch P, Hoetzenecker K, Aigner C, Radtke C, Arock M, Sperr WR, Valent P.Cells. 2024 Jan 17;13(2):173. doi: 10.3390/cells13020173.PMID: 38247864
Long segment stenosis-the narrow path to centralization in airway surgery.
Aigner C.Interdiscip Cardiovasc Thorac Surg. 2024 Feb 2;38(2):ivae004. doi: 10.1093/icvts/ivae004.PMID: 38216537
Red blood cell transfusion-related dynamics of extracellular vesicles in intensive care patients: a prospective subanalysis.
Raeven P, Karlhofer K, Sztulman LS, Brugger J, Hoetzenecker K, Domenig C, Leitner G, Posch M, Baron DM, Spittler A.Sci Rep. 2024 Jan 9;14(1):911. doi: 10.1038/s41598-023-48251-w.PMID: 38195728
Identifying High-Risk Patients for Severe Pulmonary Complications after Cardiosurgical Procedures as a Target Group for Further Assessment of Lung-Protective Strategies.
Ryz S, Menger J, Veraar C, Datler P, Mouhieddine M, Zingher F, Geilen J, Skhirtladze-Dworschak K, Ankersmit HJ, Zuckermann A, Tschernko E, Dworschak M.J Cardiothorac Vasc Anesth. 2024 Feb;38(2):445-450. doi: 10.1053/j.jvca.2023.11.030. Epub 2023 Nov 25.PMID: 38129207
PD-L1 assessment in lung cancer biopsies-pitfalls and limitations.
Gompelmann D, Sarova P, Mosleh B, Papaporfyriou A, Oberndorfer F, Idzko M, Hoda MA.Int J Biol Markers. 2024 Mar;39(1):3-8. doi: 10.1177/03936155231214273. Epub 2023 Dec 18.PMID: 38111297
Potential subtype-specific therapeutic approaches in small cell lung cancer.
Horvath L, Lang C, Boettiger K, Aigner C, Dome B, Megyesfalvi Z.Curr Opin Oncol. 2024 Jan 1;36(1):51-56. doi: 10.1097/CCO.0000000000001005. Epub 2023 Oct 18.PMID: 37865844
Revisiting aortic valve prosthesis choice in patients younger than 50 years: 10 years results of the AUTHEARTVISIT study.
Traxler D, Krotka P, Reichardt B, Copic D, Veraar C, Mildner M, Wendt R, Auer J, Mascherbauer J, Ankersmit HJ, Graf A.Eur J Cardiothorac Surg. 2024 Jan 2;65(1):ezad308. doi: 10.1093/ejcts/ezad308.PMID: 37756697
Long-Term Survival in Patients with Oligometastatic Non-Small Cell Lung Cancer by a Multimodality Treatment-Comparison with Stage III Disease.
Guberina M, Pöttgen C, Guberina N, Hoffmann C, Wiesweg M, Richlitzki C, Metzenmacher M, Aigner C, Bölükbas S, Gauler T, Eberhardt WEE, Forsting M, Herrmann K, Theegarten D, Darwiche K, Jendrossek V, Stuschke M, Schuler M.Cancers (Basel). 2024 Mar 17;16(6):1174. doi: 10.3390/cancers16061174.PMID: 38539510
A novel technique of voice-sparing cricotracheal resection.
Evermann M, Roesner I, Kranebitter V, Denk-Linnert DM, Bauer J, Schweiger T, Hoetzenecker K.JTCVS Tech. 2023 Nov 18;23:161-169. doi: 10.1016/j.xjtc.2023.11.005. eCollection 2024 Feb.PMID: 38352015
Extension of Cold Static Donor Lung Preservation at 10°C.
Ali A, Hoetzenecker K, Luis Campo-Cañaveral de la Cruz J, Schwarz S, Barturen MG, Tomlinson G, Yeung J, Donahoe L, Yasufuku K, Pierre A, de Perrot M, Waddell TK, Keshavjee S, Cypel M.NEJM Evid. 2023 Jun;2(6):EVIDoa2300008. doi: 10.1056/EVIDoa2300008. Epub 2023 Apr 20.PMID: 38320127
Single nucleus RNA sequencing reveals glial cell type-specific responses to ischemic stroke.
Bormann D, Knoflach M, Poreba E, Riedl CJ, Testa G, Orset C, Levilly A, Cottereau A, Jauk P, Hametner S, Golabi B, Copic D, Klas K, Direder M, Kühtreiber H, Salek M, Zur Nedden S, Baier-Bitterlich G, Kiechl S, Haider C, Endmayr V, Höftberger R, Ankersmit HJ, Mildner M.bioRxiv [Preprint]. 2023 Dec 26:2023.12.26.573302. doi: 10.1101/2023.12.26.573302.PMID: 38234821
Analysis of Pain Management after Anatomic VATS Resection in Austrian Thoracic Surgery Units. Ponholzer F, Schweiger T, Ghanim B, Maier H, Hutter J, Tomaselli F, Krause A, Müller M, Lindenmann J, Spruk G, Augustin F.J Clin Med. 2023 Dec 22;13(1):80. doi: 10.3390/jcm13010080.PMID: 38202087
High Rate of Passenger Lymphocyte Syndrome after ABO Minor Incompatible Lung Transplantation.
Kohl MM, Schwarz S, Jaksch P, Muraközy G, Kurz M, Schönbacher M, Tolios A, Frommlet F, Hoetzenecker K, Körmöczi GF.Am J Respir Crit Care Med. 2023 Dec 11. doi: 10.1164/rccm.202306-1107OC. Online ahead of print.PMID: 38078854
Postoperative Radiation Therapy for Thymic Carcinoma: An Analysis of the International Thymic Malignancy Interest Group/European Society of Thoracic Surgeons Database.
Rimner A, Ahmad U, Lobaugh SM, Zhang Z, Shepherd AF, Huang J, Antonicelli A, Girard N, Moser B, Filosso P, Lucchi M, Marom EM, Roden A, Detterbeck F, Ruffini E, Simone CB 2nd.J Thorac Oncol. 2023 Dec 8:S1556-0864(23)02416-4. doi: 10.1016/j.jtho.2023.12.011. Online ahead of print.PMID: 38070599
HUNCHEST-II contributes to a shift to earlier-stage lung cancer detection: final results of a nationwide screening program.
Kerpel-Fronius A, Megyesfalvi Z, Markóczy Z, Solymosi D, Csányi P, Tisza J, Kecskés A, Baranyi B, Csánky E, Dóka A, Gálffy G, Göcző K, Győry C, Horváth Z, Juhász T, Kállai Á, Kincses ZT, Király Z, Király-Incze E, Kostyál L, Kovács A, Kovács A, Kuczkó É, Makra Z, Maurovich Horvát P, Merth G, Moldoványi I, Müller V, Pápai-Székely Z, Papp D, Polgár C, Rózsa P, Sárosi V, Szalai Z, Székely A, Szuhács M, Tárnoki D, Tavaszi G, Turóczi-Kirizs R, Tóth L, Urbán L, Vaskó A, Vigh É, Dome B, Bogos K.Eur Radiol. 2023 Nov 3. doi: 10.1007/s00330-023-10379-8. Online ahead of print.PMID: 37921926
Computed Tomography-Based Quantitative Texture Analysis and Gut Microbial Community Signatures Predict Survival in Non-Small Cell Lung Cancer.
Dora D, Weiss GJ, Megyesfalvi Z, Gállfy G, Dulka E, Kerpel-Fronius A, Berta J, Moldvay J, Dome B, Lohinai Z.Cancers (Basel). 2023 Oct 21;15(20):5091. doi: 10.3390/cancers15205091.PMID: 37894458
Targeting YB-1 via entinostat enhances cisplatin sensitivity of pleural mesothelioma in vitro and in vivo.
Schelch K, Emminger D, Zitta B, Johnson TG, Kopatz V, Eder S, Ries A, Stefanelli A, Heffeter P, Hoda MA, Hoetzenecker K, Dome B, Berger W, Reid G, Grusch M.Cancer Lett. 2023 Oct 10;574:216395. doi: 10.1016/j.canlet.2023.216395. Epub 2023 Sep 18.PMID: 37730104
Entinostat Enhances the Efficacy of Chemotherapy in Small Cell Lung Cancer Through S-phase Arrest and Decreased Base Excision Repair.
Solta A, Boettiger K, Kovács I, Lang C, Megyesfalvi Z, Ferk F, Mišík M, Hoetzenecker K, Aigner C, Kowol CR, Knasmueller S, Grusch M, Szeitz B, Rezeli M, Dome B, Schelch K.Clin Cancer Res. 2023 Nov 14;29(22):4644-4659. doi: 10.1158/1078-0432.CCR-23-1795.PMID: 37725585
The hemodynamic interplay between pulmonary ischemia-reperfusion injury and right ventricular function in lung transplantation: a translational porcine model.
Orlitová M, Verbelen T, Frick AE, Vanstapel A, Van Beersel D, Ordies S, Van Slambrouck J, Kaes J, Jin X, Coudyzer W, Verleden SE, Verleden GM, Vanaudenaerde BM, Van Raemdonck DE, Vos R, Ceulemans LJ, Claus P, Neyrinck AP.Am J Physiol Lung Cell Mol Physiol. 2023 Nov 1;325(5):L675-L688. doi: 10.1152/ajplung.00281.2022. Epub 2023 Sep 19.PMID: 37724349
Krebs von den Lungen 6 (KL-6) is a novel diagnostic and prognostic biomarker in pleural mesothelioma.
Stockhammer P, Baumeister H, Ploenes T, Bonella F, Theegarten D, Dome B, Pirker C, Berger W, Hegedüs L, Baranyi M, Schuler M, Deshayes S, Bölükbas S, Aigner C, Blanquart C, Hegedüs B.Lung Cancer. 2023 Nov;185:107360. doi: 10.1016/j.lungcan.2023.107360. Epub 2023 Sep 7.PMID: 37713954
Unfolding the secrets of small cell lung cancer progression: Novel approaches and insights through rapid autopsies.
Megyesfalvi Z, Heeke S, Drapkin BJ, Solta A, Kovacs I, Boettiger K, Horvath L, Ernhofer B, Fillinger J, Renyi-Vamos F, Aigner C, Schelch K, Lang C, Marko-Varga G, Gay CM, Byers LA, Morris BB, Heymach JV, Van Loo P, Hirsch FR, Dome B.Cancer Cell. 2023 Sep 11;41(9):1535-1540. doi: 10.1016/j.ccell.2023.08.007.PMID: 37699331
Pentastatin, a matrikine of the collagen IVα5, is a novel endogenous mediator of pulmonary endothelial dysfunction.
Mutgan AC, Jandl K, Radic N, Valzano F, Kolb D, Hoffmann J, Foris V, Wilhelm J, Boehm PM, Hoetzenecker K, Olschewski A, Olschewski H, Heinemann A, Wygrecka M, Marsh LM, Kwapiszewska G.Am J Physiol Cell Physiol. 2023 Nov 1;325(5):C1294-C1312. doi: 10.1152/ajpcell.00391.2023. Epub 2023 Sep 11.PMID: 37694286
Thymectomy in myasthenia gravis.
Rath J, Moser B, Zimprich F.Curr Opin Neurol. 2023 Oct 1;36(5):416-423. doi: 10.1097/WCO.0000000000001189. Epub 2023 Jul 25.PMID: 37639450
How We Would Treat Our Own Lung Transplantation: A Multidisciplinary and International Perspective.
Martin AK, Reed AK, Hoetzenecker K, Fessler J.J Cardiothorac Vasc Anesth. 2023 Nov;37(11):2207-2214. doi: 10.1053/j.jvca.2023.07.042. Epub 2023 Aug 3.PMID: 37635039
Treprostinil Reconstitutes Mitochondrial Organisation and Structure in Idiopathic Pulmonary Fibrosis Cells.
Fang L, Chen WC, Jaksch P, Molino A, Saglia A, Roth M, Lambers C.Int J Mol Sci. 2023 Jul 29;24(15):12148. doi: 10.3390/ijms241512148.PMID: 37569523
Primary and hTERT-Transduced Mesothelioma-Associated Fibroblasts but Not Primary or hTERT-Transduced Mesothelial Cells Stimulate Growth of Human Mesothelioma Cells.
Ries A, Slany A, Pirker C, Mader JC, Mejri D, Mohr T, Schelch K, Flehberger D, Maach N, Hashim M, Hoda MA, Dome B, Krupitza G, Berger W, Gerner C, Holzmann K, Grusch M.Cells. 2023 Aug 5;12(15):2006. doi: 10.3390/cells12152006.PMID: 37566084
Evaluation of PD-1 T lymphocytes in bronchoalveolar lavage in lung cancer compared to benign lung diseases.
Hammer B, Bal C, Gysan M, Zehetmayer S, Geleff S, Zech A, Kramer M, Ayazseven S, Idzko M, Mosleh B, Hoda MA, Gompelmann D.Clin Exp Med. 2023 Dec;23(8):5177-5182. doi: 10.1007/s10238-023-01146-6. Epub 2023 Aug 3.PMID: 37535195
Microenvironmental regulation of T-cells in pulmonary hypertension.
Plecitá-Hlavatá L, Brázdová A, Křivonosková M, Hu CJ, Phang T, Tauber J, Li M, Zhang H, Hoetzenecker K, Crnkovic S, Kwapiszewska G, Stenmark KR.Front Immunol. 2023 Jul 11;14:1223122. doi: 10.3389/fimmu.2023.1223122. eCollection 2023.PMID: 37497214
DOTATOC PET/CT imaging of a typical carcinoid tumor in a human ex-vivo perfused lung lobe.
Slama A, Schaarschmidt BM, Okumus Ö, Herrmann K, Aigner C, Collaud S, Hautzel H.Quant Imaging Med Surg. 2023 Jul 1;13(7):4716-4722. doi: 10.21037/qims-22-1188. Epub 2023 Jun 15.PMID: 37456303
Plasma Small Extracellular Vesicle Cardiac miRNA Expression in Patients with Ischemic Heart Failure, Randomized to Percutaneous Intramyocardial Treatment of Adipose Derived Stem Cells or Placebo: Subanalysis of the SCIENCE Study.
Traxler D, Dannenberg V, Zlabinger K, Gugerell A, Mester-Tonczar J, Lukovic D, Spannbauer A, Hasimbegovic E, Kastrup J, Gyöngyösi M.Int J Mol Sci. 2023 Jun 26;24(13):10647. doi: 10.3390/ijms241310647.PMID: 37445825
See one, do one, teach one?-It is all about the endpoints.
Aigner C. Eur J Cardiothorac Surg. 2023 Jul 3;64(1):ezad258. doi: 10.1093/ejcts/ezad258.PMID: 37432418
Circulating FGF18 is decreased in pleural mesothelioma but not correlated with disease prognosis.
Mosleh B, Schelch K, Mohr T, Klikovits T, Wagner C, Ratzinger L, Dong Y, Sinn K, Ries A, Berger W, Grasl-Kraupp B, Hoetzenecker K, Laszlo V, Dome B, Hegedus B, Jakopovic M, Hoda MA, Grusch M. Thorac Cancer. 2023 Aug;14(22):2177-2186. doi: 10.1111/1759-7714.15004. Epub 2023 Jun 21.PMID: 37340889
Clinical insights into small cell lung cancer: Tumor heterogeneity, diagnosis, therapy, and future directions.
Megyesfalvi Z, Gay CM, Popper H, Pirker R, Ostoros G, Heeke S, Lang C, Hoetzenecker K, Schwendenwein A, Boettiger K, Bunn PA Jr, Renyi-Vamos F, Schelch K, Prosch H, Byers LA, Hirsch FR, Dome B.CA Cancer J Clin. 2023 Nov-Dec;73(6):620-652. doi: 10.3322/caac.21785. Epub 2023 Jun 17.PMID: 37329269
Elevation of neutrophil-derived factors in patients after multiple trauma.
Lingitz MT, Wollner G, Bauer J, Kuehtreiber H, Mildner M, Copic D, Bormann D, Direder M, Krenn CG, Haider T, Negrin LL, Ankersmit HJ.J Cell Mol Med. 2023 Jul;27(13):1859-1866. doi: 10.1111/jcmm.17786. Epub 2023 Jun 16.PMID: 37328954
Defining a natural killer cell-enriched molecular rejection-like state in lung transplant transbronchial biopsies.
Gauthier PT, Mackova M, Hirji A, Weinkauf J, Timofte IL, Snell GI, Westall GP, Havlin J, Lischke R, Zajacová A, Simonek J, Hachem R, Kreisel D, Levine D, Kubisa B, Piotrowska M, Juvet S, Keshavjee S, Jaksch P, Klepetko W, Halloran K, Halloran PF.Am J Transplant. 2023 Dec;23(12):1922-1938. doi: 10.1016/j.ajt.2023.06.003. Epub 2023 Jun 7.PMID: 37295720
Lipidomics for diagnosis and prognosis of pulmonary hypertension.
Bordag N, Nagy BM, Zügner E, Ludwig H, Foris V, Nagaraj C, Biasin V, Bodenhofer U, Magnes C, Maron BA, Ulrich S, Lange TJ, Hötzenecker K, Pieber T, Olschewski H, Olschewski A.medRxiv [Preprint]. 2023 Nov 29:2023.05.17.23289772. doi: 10.1101/2023.05.17.23289772.PMID: 37292870
PD-1 and PD-L1 expression in rare lung tumors.
Gyulai M, Megyesfalvi Z, Reiniger L, Harko T, Ferencz B, Karsko L, Agocs L, Fillinger J, Dome B, Szallasi Z, Moldvay J.Pathol Oncol Res. 2023 May 18;29:1611164. doi: 10.3389/pore.2023.1611164. eCollection 2023.PMID: 37274772
Laser ablation-inductively coupled plasma-mass spectrometry analysis reveals differences in chemotherapeutic drug distribution in surgically resected pleural mesothelioma.
Tisza A, Klikovits T, Benej M, Torok S, Szeitz B, Valko Z, Hoda MA, Hegedus B, Bonta M, Nischkauer W, Hoetzenecker K, Limbeck A, Schelch K, Laszlo V, Megyesfalvi Z, Dome B.Br J Clin Pharmacol. 2023 Nov;89(11):3364-3374. doi: 10.1111/bcp.15813. Epub 2023 Jul 14.PMID: 37272312
Comparative expression analysis of immune-related markers in surgically resected lung neuroendocrine neoplasms.
Ferencz B, Megyesfalvi Z, Csende K, Fillinger J, Poór V, Lantos A, Pipek O, Sólyom-Tisza A, Rényi-Vámos F, Schelch K, Lang C, Schwendenwein A, Boettiger K, László V, Hoetzenecker K, Döme B, Berta J.Lung Cancer. 2023 Jul;181:107263. doi: 10.1016/j.lungcan.2023.107263. Epub 2023 May 30.PMID: 37270937
Therapeutic Application of Cell Secretomes in Cutaneous Wound Healing.
Bormann D, Gugerell A, Ankersmit HJ, Mildner M.J Invest Dermatol. 2023 Jun;143(6):893-912. doi: 10.1016/j.jid.2023.02.019.PMID: 37211377
Non-small cell lung cancer patients treated with Anti-PD1 immunotherapy show distinct microbial signatures and metabolic pathways according to progression-free survival and PD-L1 status.
Dora D, Ligeti B, Kovacs T, Revisnyei P, Galffy G, Dulka E, Krizsán D, Kalcsevszki R, Megyesfalvi Z, Dome B, Weiss GJ, Lohinai Z.Oncoimmunology. 2023 May 12;12(1):2204746. doi: 10.1080/2162402X.2023.2204746. eCollection 2023.PMID: 37197440
The Effect of Prone Positioning After Lung Transplantation.
Frick AE, Schiefer J, Maleczek M, Schwarz S, Benazzo A, Rath A, Kulu A, Hritcu R, Faybik P, Schaden E, Jaksch P, Tschernko E, Frommlet F, Markstaller K, Hoetzenecker K.Ann Thorac Surg. 2023 May 5:S0003-4975(23)00472-1. doi: 10.1016/j.athoracsur.2023.04.036. Online ahead of print.PMID: 37150273
The Secretome of Irradiated Peripheral Mononuclear Cells Attenuates Hypertrophic Skin Scarring.
Vorstandlechner V, Copic D, Klas K, Direder M, Golabi B, Radtke C, Ankersmit HJ, Mildner M.Pharmaceutics. 2023 Mar 25;15(4):1065. doi: 10.3390/pharmaceutics15041065.PMID: 37111549
Use of Recombinant Activated Factor VII in Bleeding Lung Transplant Patients Undergoing Perioperative ECMO Therapy.
Laxar D, Schaden E, Wiegele M, Hötzenecker K, Schwarz S, Gratz J.J Clin Med. 2023 Apr 21;12(8):3020. doi: 10.3390/jcm12083020.PMID: 37109356
Extracorporeal Photopheresis Suppresses Transplant Fibrosis by Inducing Decorin Expression in Alveolar Macrophages.
Hutchinson JA, Benazzo A.Transplantation. 2023 May 1;107(5):1010-1012. doi: 10.1097/TP.0000000000004536. Epub 2023 Apr 22.PMID: 37097979
Lymph Node Log-Odds Ratio Accurately Defines Prognosis in Resectable Non-Small Cell Lung Cancer.
Benej M, Klikovits T, Krajc T, Bohanes T, Schulte L, Hochmair MJ, Watzka S, Mosleh B, Hoetzenecker K, Aigner C, Hoda MA, Mueller MR.Cancers (Basel). 2023 Mar 31;15(7):2082. doi: 10.3390/cancers15072082.PMID: 37046743
Red blood cell transfusion-related eicosanoid profiles in intensive care patients-A prospective, observational feasibility study.
Raeven P, Hagn G, Niederstaetter L, Brugger J, Bayer-Blauensteiner S, Domenig C, Hoetzenecker K, Posch M, Leitner G, Gerner C, Baron DM.Front Physiol. 2023 Mar 16;14:1164926. doi: 10.3389/fphys.2023.1164926. eCollection 2023.PMID: 37008004
The usefulness of MMP-9, TIMP-1 and MMP-9/TIMP-1 ratio for diagnosis and assessment of COPD severity.
Dimic-Janjic S, Hoda MA, Milenkovic B, Kotur-Stevuljevic J, Stjepanovic M, Gompelmann D, Jankovic J, Miljkovic M, Milin-Lazovic J, Djurdjevic N, Maric D, Milivojevic I, Popevic S.Eur J Med Res. 2023 Mar 20;28(1):127. doi: 10.1186/s40001-023-01094-7.PMID: 36935521
Case Report: Recurrence of Acute Respiratory Distress Syndrome After Bilateral Lung Transplantation.
Schoeberl AK, Schwarz S, Benazzo A, Schweiger T, Lang G, Jaksch P, Hoetzenecker K.Transplant Proc. 2023 Apr;55(3):697-700. doi: 10.1016/j.transproceed.2023.02.030. Epub 2023 Feb 23.PMID: 36935335
Dual targeting of BCL-2 and MCL-1 in the presence of BAX breaks venetoclax resistance in human small cell lung cancer.
Valko Z, Megyesfalvi Z, Schwendenwein A, Lang C, Paku S, Barany N, Ferencz B, Horvath-Rozsas A, Kovacs I, Schlegl E, Pozonec V, Boettiger K, Rezeli M, Marko-Varga G, Renyi-Vamos F, Hoda MA, Klikovits T, Hoetzenecker K, Grusch M, Laszlo V, Dome B, Schelch K.Br J Cancer. 2023 May;128(10):1850-1861. doi: 10.1038/s41416-023-02219-9. Epub 2023 Mar 14.PMID: 36918717
Aggrecan accumulates at sites of increased pulmonary arterial pressure in idiopathic pulmonary arterial hypertension.
van der Have O, Mead TJ, Westöö C, Peruzzi N, Mutgan AC, Norvik C, Bech M, Struglics A, Hoetzenecker K, Brunnström H, Westergren-Thorsson G, Kwapiszewska G, Apte SS, Tran-Lundmark K.Pulm Circ. 2023 Feb 21;13(1):e12200. doi: 10.1002/pul2.12200. eCollection 2023 Jan.PMID: 36824691
Neoadjuvant immune-checkpoint inhibitors in lung cancer - a primer for radiologists.
Kifjak D, Hochmair MJ, Krenbek D, Milos RI, Heidinger BH, Prayer F, Röhrich S, Watzenboeck ML, Oberndorfer F, Klikovits T, Aigner C, Sinn K, Hoda MA, Hoetzenecker K, Haug AR, Prosch H, Beer L.Eur J Radiol. 2023 Apr;161:110732. doi: 10.1016/j.ejrad.2023.110732. Epub 2023 Feb 8.PMID: 36804313
Left Ventricular Filling Pressure in Chronic Thromboembolic Pulmonary Hypertension.
Gerges C, Pistritto AM, Gerges M, Friewald R, Hartig V, Hofbauer TM, Reil B, Engel L, Dannenberg V, Kastl SP, Skoro-Sajer N, Moser B, Taghavi S, Klepetko W, Lang IM.J Am Coll Cardiol. 2023 Feb 21;81(7):653-664. doi: 10.1016/j.jacc.2022.11.049.PMID: 36792280
Lungs Preserved on Ice or in a Refrigerator? Prolonged Static Lung Storage at 10 °C.
Cypel M, Hötzenecker K, Campo-Cañaveral de la Cruz J, Kukreja J, Suarez E, Smith M, Bush EL.Ann Thorac Surg. 2023 May;115(5):1095-1097. doi: 10.1016/j.athoracsur.2022.12.047. Epub 2023 Feb 12.PMID: 36787842
Antithymocyte Globulin Inhibits CD8+ T Cell Effector Functions via the Paracrine Induction of PDL-1 on Monocytes.
Copic D, Direder M, Klas K, Bormann D, Laggner M, Ankersmit HJ, Mildner M.Cells. 2023 Jan 20;12(3):382. doi: 10.3390/cells12030382.PMID: 36766722
Cumulative UV Exposure or a Modified SCINEXA™-Skin Aging Score Do Not Play a Substantial Role in Predicting the Risk of Developing Keratinocyte Cancers after Solid Organ Transplantation-A Case Control Study.
Borik-Heil L, Endler G, Parson W, Zuckermann A, Schnaller L, Uyanik-Ünal K, Jaksch P, Böhmig G, Cejka D, Staufer K, Hielle-Wittmann E, Rasoul-Rockenschaub S, Wolf P, Sunder-Plassmann R, Geusau A.Cancers (Basel). 2023 Jan 30;15(3):864. doi: 10.3390/cancers15030864.PMID: 36765822
Apelin-17 to diagnose idiopathic pulmonary arterial hypertension: A biomarker study.
Foris V, Kovacs G, Avian A, Bálint Z, Douschan P, Ghanim B, Klepetko W, Olschewski A, Olschewski H.Front Physiol. 2023 Jan 4;13:986295. doi: 10.3389/fphys.2022.986295. eCollection 2022.PMID: 36685176
Mesothelioma-associated fibroblasts enhance proliferation and migration of pleural mesothelioma cells via c-Met/PI3K and WNT signaling but do not protect against cisplatin.
Ries A, Flehberger D, Slany A, Pirker C, Mader JC, Mohr T, Schelch K, Sinn K, Mosleh B, Hoda MA, Dome B, Dolznig H, Krupitza G, Müllauer L, Gerner C, Berger W, Grusch M.J Exp Clin Cancer Res. 2023 Jan 23;42(1):27. doi: 10.1186/s13046-022-02582-0.PMID: 36683050
Reproducibility of the 6-minute walk test in lung transplant recipients.
Ebenbichler GR, Murakoezy G, Kohlmann J, Habenicht R, Kienbacher T, Jaksch P, Mair P, Hoetzenecker K.Wien Klin Wochenschr. 2023 Oct;135(19-20):517-527. doi: 10.1007/s00508-022-02132-w. Epub 2022 Dec 28.PMID: 36576557
Proteomic analysis of brain metastatic lung adenocarcinoma reveals intertumoral heterogeneity and specific alterations associated with the timing of brain metastases.
Woldmar N, Schwendenwein A, Kuras M, Szeitz B, Boettiger K, Tisza A, László V, Reiniger L, Bagó AG, Szállási Z, Moldvay J, Szász AM, Malm J, Horvatovich P, Pizzatti L, Domont GB, Rényi-Vámos F, Hoetzenecker K, Hoda MA, Marko-Varga G, Schelch K, Megyesfalvi Z, Rezeli M, Döme B.ESMO Open. 2023 Feb;8(1):100741. doi: 10.1016/j.esmoop.2022.100741. Epub 2022 Dec 16.PMID: 36527824
Divergent Roles of Ephrin-B2/EphB4 Guidance System in Pulmonary Hypertension.
Crnkovic S, Rittchen S, Jandl K, Gindlhuber J, Zabini D, Mutgan AC, Valzano F, Boehm PM, Hoetzenecker K, Toller W, Veith C, Heinemann A, Schermuly RT, Olschewski A, Marsh LM, Kwapiszewska G.Hypertension. 2023 Feb;80(2):e17-e28. doi: 10.1161/HYPERTENSIONAHA.122.19479. Epub 2022 Dec 15.PMID: 36519465
The American Association for Thoracic Surgery (AATS) 2022 Expert Consensus Document: The use of mechanical circulatory support in lung transplantation.
Expert Consensus Panel:; Hartwig M, van Berkel V, Bharat A, Cypel M, Date H, Erasmus M, Hoetzenecker K, Klepetko W, Kon Z, Kukreja J, Machuca T, McCurry K, Mercier O, Opitz I, Puri V, Van Raemdonck D.J Thorac Cardiovasc Surg. 2023 Jan;165(1):301-326. doi: 10.1016/j.jtcvs.2022.06.024. Epub 2022 Oct 26.PMID: 36517135
HLA-E-restricted immune responses are crucial for the control of EBV infections and the prevention of PTLD.
Vietzen H, Furlano PL, Cornelissen JJ, Böhmig GA, Jaksch P, Puchhammer-Stöckl E.Blood. 2023 Mar 30;141(13):1560-1573. doi: 10.1182/blood.2022017650.PMID: 36477802
Overcoming the Limits of Lung Transplantation: 10°C Static Cold Preservation.
Campo-Cañaveral de la Cruz JL, Gil Barturen M, Ali A, Hoetzenecker K, Cypel M.Arch Bronconeumol. 2023 May;59(5):282-283. doi: 10.1016/j.arbres.2022.11.004. Epub 2022 Nov 21.PMID: 36473818
Thoracic irradiation as consolidation therapy in patients with extensive-stage small cell lung cancer.
Berta J, Rózsás A, Megyesfalvi Z, Ostoros G, Döme B.Curr Opin Oncol. 2023 Jan 1;35(1):54-60. doi: 10.1097/CCO.0000000000000911. Epub 2022 Nov 16.PMID: 36420570
The human cytomegalovirus-specific and UL40-mediated imprint in the natural killer cell repertoire is associated with antibody-mediated rejection in lung transplant recipients.
Vietzen H, Jaksch P, Puchhammer-Stöckl E.J Heart Lung Transplant. 2023 Mar;42(3):305-314. doi: 10.1016/j.healun.2022.10.014. Epub 2022 Oct 21.PMID: 36376218
Notch1 Induces Defective Epithelial Surfactant Processing and Pulmonary Fibrosis.
Wasnick R, Korfei M, Piskulak K, Henneke I, Wilhelm J, Mahavadi P, Dartsch RC, von der Beck D, Koch M, Shalashova I, Weiss A, Klymenko O, Askevold I, Fink L, Witt H, Hackstein H, El Agha E, Bellusci S, Klepetko W, Königshoff M, Eickelberg O, Schermuly RT, Braun T, Seeger W, Ruppert C, Guenther A.Am J Respir Crit Care Med. 2023 Feb 1;207(3):283-299. doi: 10.1164/rccm.202105-1284OC.PMID: 36047984
Protein Expression of immune checkpoints STING and MHCII in small cell lung cancer.
Dora D, Rivard C, Yu H, Pickard SL, Laszlo V, Harko T, Megyesfalvi Z, Gerdan C, Dinya E, Hoetzenecker K, Hirsch FR, Lohinai Z, Dome B.Cancer Immunol Immunother. 2023 Mar;72(3):561-578. doi: 10.1007/s00262-022-03270-w. Epub 2022 Aug 17.PMID: 35978199
Expression and regulation of Siglec-6 (CD327) on human mast cells and basophils.
Smiljkovic D, Herrmann H, Sadovnik I, Gamperl S, Berger D, Stefanzl G, Eisenwort G, Hoermann G, Kopanja S, Dorofeeva Y, Focke-Tejkl M, Jaksch P, Hoetzenecker K, Szepfalusi Z, Valenta R, Arock M, Valent P.J Allergy Clin Immunol. 2023 Jan;151(1):202-211. doi: 10.1016/j.jaci.2022.07.018. Epub 2022 Aug 8.PMID: 35953001
Correlation of PD-L1 expression on tumour cells between diagnostic biopsies and surgical specimens of lung cancer in real life with respect to biopsy techniques and neoadjuvant treatment.
Gompelmann D, Sinn K, Brugger J, Bernitzky D, Mosleh B, Prosch H, Geleff S, Blessing A, Tiefenbacher A, Hoetzenecker K, Idzko M, Hoda MA.J Cancer Res Clin Oncol. 2023 May;149(5):1747-1754. doi: 10.1007/s00432-022-04080-4. Epub 2022 Jun 16.PMID: 35708777
Lung transplantation for acute respiratory distress syndrome.
Hoetzenecker K, Schwarz S, Keshavjee S, Cypel M.J Thorac Cardiovasc Surg. 2023 Apr;165(4):1596-1601. doi: 10.1016/j.jtcvs.2022.02.033. Epub 2022 Feb 23.PMID: 35379475
Multi-omics profiling predicts allograft function after lung transplantation
Watzenböck M., Gorki A., Quattrone F., Gawish R., Schwarz S., Lambers C., Jaksch P., Lakovits K., Zahálka S., Rahimi N., Starkl P., Symmank D., Artner T., Pattaroni C., Fortelny N., Kristaps K., Frommlet F., Marsland B., Hötzenecker K., Widder S., Knapp S. Eur Respir J. 2022 Feb 3;59(2):2003292. doi: 10.1183/13993003.03292-2020. Print 2022 Feb. PMID: 34244315
Lung transplantation for acute respiratory distress syndrome: A multicenter experience
Frick A., Gan C., Vos R. , Schwarz S., Kraft F., Kifjak D., Neyrinck A., Van Raemdonck D., Klepetko W., Jaksch P., Verschuuren E., Hötzenecker K. . Multicenter Study. Am J Transplant. 2022 Jan;22(1):144-153. doi: 10.1111/ajt.16759. Epub 2021 Jul 24. PMID: 34254423
A randomized controlled trial of liposomal cyclosporine A for inhalation in the prevention of bronchiolitis obliterans syndrome following lung transplantation
Neurohr C., Kneidinger N., Ghiani A., Monforte V., Knoop C., Jaksch P., Parmar J., Ussetti P., Sole A., Mueller-Quernheim J., Kessler R., Wirtz H., Boerner G., Denk O., Fernandes S., Behr J. Am J Transplant. 2022 Jan;22(1):222-229. doi: 10.1111/ajt.16858. Epub 2021 Oct 18. PMID: 34587371
Oblique Carinal End-to-end Anastomosis for Pig Bronchus in Organ Donor and Lung Transplant Recipient.
Böhm P., Sinn K., Schwarz S., Kollmann D., Berlakovich G., Hötzenecker K. Case Reports. Ann Thorac Surg. 2022 Mar;113(3):e195-e197. doi: 10.1016/j.athoracsur.2021.05.029. Epub 2021 Jun 5. PMID: 34102182
Age-Dependent and Pathway-Specific Bimodal Action of Nicotine on Synaptic Plasticity in the Hippocampus of Mice Lacking the miR-132/212 Genes
Stojanovic T., Velarde Gamez R., Schuld G., Bormann D. , Cabatic M., Uhrin P., Lubec G., Monje Quiroga F. Cells. 2022 Jan 13;11(2):261. doi: 10.3390/cells11020261. PMID: 35053378
Differential LysoTracker Uptake Defines Two Populations of Distal Epithelial Cells in Idiopathic Pulmonary Fibrosis
Wasnick R., Shalashova I., Wilhelm J., Khadim A., Schmidt N., Hackstein H., Hecker A., Hötzenecker K., Seeger W., Bellusci S., El Agha E., Ruppert C., Guenther A.. Cells. 2022 Jan 11;11(2):235. doi: 10.3390/cells11020235. PMID: 35053350
Secretome of Stressed Peripheral Blood Mononuclear Cells Alters Transcriptome Signature in Heart, Liver, and Spleen after an Experimental Acute Myocardial Infarction: An In Silico Analysis
Mildner C., Copic D., Zimmermann M., Lichtenauer M., Direder M., Klas K., Bormann D., Gugerell A., Moser B., Hötzenecker K., Beer L., Pavone-Gyöngyösi M., Ankersmit H., Laggner M.. Biology (Basel). 2022 Jan 13;11(1):116. doi: 10.3390/biology11010116. PMID: 35053121
Commentary: A journey of a thousand miles begins with a single step
Frick A., Hötzenecker K.. Editorial. J Thorac Cardiovasc Surg. 2022 Feb;163(2):e124-e125. doi: 10.1016/j.jtcvs.2021.01.116. Epub 2021 Feb 6. PMID: 33648727
Early implementation of renal replacement therapy after lung transplantation does not impair long-term kidney function in patients with idiopathic pulmonary arterial hypertension
Benazzo A., Bajorek L., Morscher A., Schrutka L., Schaden E., Klepetko W., Hötzenecker K..
J Thorac Cardiovasc Surg. 2022 Feb;163(2):524-535.e3. doi: 10.1016/j.jtcvs.2021.05.034. Epub 2021 Jun 1. PMID: 34144824
Transcriptional differences of lipid-metabolizing enzymes in sebocytes derived from sebaceous glands of the skin and preputial glands
Klas K., Copic D., Direder M., Laggner M., Prucksamas P., Gruber F., Ankersmit H., Mildner M.. Int J Mol Sci. 2021 Oct 27;22(21):11631. doi: 10.3390/ijms222111631. PMID: 34769061
An unexpected role of Schwann cells in keloid formation
Direder M., Weiss T., Copic D., Vorstandlechner V., Klas K., Laggner M., Wielscher M., Radtke C., Golabi B., Ankersmit H., Mildner M..
Expanded Indication for Magnetic Sphincter Augmentation: Outcomes in Weakly Acidic Reflux Compared to Standard GERD Patients
Nikolic M., Matic A., Feka J., Gensthaler L., Kristo I., Osmokrovic B., Riegler F., Mosleh B., Schoppmann S.. J Gastrointest Surg. 2022; 26(3): 532–541. Published online 2021 Sep 29. doi: 10.1007/s11605-021-05152-5. PMID: 34590216
Commentary: The Ethical Dilemma of Multiple Listing
Hötzenecker K.. Semin Thorac Cardiovasc Surg. 2022 Spring;34(1):336. doi: 10.1053/j.semtcvs.2021.04.045. Epub 2021 May 15. PMID: 34004294
MiR-21 in Lung Transplant Recipients With Chronic Lung Allograft Dysfunction
Miyahara N., Benazzo A., Oberndorfer F., Iwasaki A., Laszlo V., Dome B., Hoda M., Jaksch P., Klepetko W., Hötzenecker K.. Transpl Int. 2022; 35: 10184. Published online 2022 Jan 13. doi: 10.3389/ti.2021.10184. PMID: 35185369
Severity of thermal burn injury is associated with systemic neutrophil activation
Laggner M., Lingitz M., Copic D., Direder M., Klas K., Bormann D., Gugerell A., Moser B., Radtke C., Hacker S., Mildner M., Ankersmit H., Haider T.. Sci Rep. 2022 Jan 31;12(1):1654.
doi: 10.1038/s41598-022-05768-w. PMID: 35102298
Functional Precision Medicine Provides Clinical Benefit in Advanced Aggressive Hematologic Cancers and Identifies Exceptional Responders
Kornauth C., Pemovska T., Bayer G., Bergmann M., Eder S., Esterbauer H., Exner R., Forte M., Gaiger A., Gstöttner W., Hacker M., Hauswirth A., Hoda M., Jäger U., Kazianka L., Kenner L., Kiesewetter-Wiederkehr B., Le T., Lubowitzki S., Mayerhöfer M., Merkel O., Müllauer L., Pichler A., Porpáczy E., Prager G., Raderer M., Ristl R., Schiefer A., Schmolke A., Schwarzinger I., Selzer E., Sillaber C., Skrabs C., Sperr W., Thalhammer R., Valent P., van der Kouwe E., Vanura K., Waldstein C., Zielinski C., Simonitsch-Klupp I., Superti-Furga G., Staber P.. Cancer Discov. 2022 Feb;12(2):372-387. doi: 10.1158/2159-8290.CD-21-0538. Epub 2021 Oct 11. PMID: 34635570
EGR1 Is Implicated in Right Ventricular Cardiac Remodeling Associated with Pulmonary Hypertension
Laggner M., Oberndorfer F., Golabi B., Bauer J., Zuckermann A., Hacker P., Lang I., Skoro-Sajer N., Gerges C., Taghavi S., Jaksch P., Mildner M., Ankersmit H., Moser B.. Biology (Basel). 2022 Apr 28;11(5):677. doi: 10.3390/biology11050677. PMID: 35625405
COVID-19 as a putative trigger of anti-MDA5-associated dermatomyositis with acute respiratory distress syndrome (ARDS) requiring lung transplantation, a case report
K. Anderle, K. Machold, H. Kiener, D. Bormann, K. Hötzenecker, S. Geleff, H. Prosch, F. Laccone, P. Heil, P. Petzelbauer, D. Aletaha, S. Blüml, K. Kastrati. BMC Rheumatol. 2022; 6: 42. Published online 2022 Jul 13. doi: 10.1186/s41927-022-00271-1. PMID: 35821079
Multimodal Treatment of Malignant Pleural Mesothelioma: Real-World Experience with 112 Patients
A. Holzknecht, O. Illini, M. Hochmair, D. Krenbek, U. Setinek, F. Huemer, E. Bitterlich, C. Kaindl, V. Getman, A. Akan, M. Weber, G. Leobacher, A. Valipour, M. Mueller, S. Watzka.
Cancers (Basel). 2022 May; 14(9): 2245. Published online 2022 Apr 30. doi: 10.3390/cancers14092245. PMID: 35565374
Mechanisms of Action of Extracorporeal Photopheresis in the Control of Bronchiolitis Obliterans Syndrome (BOS): Involvement of Circulating miRNAs
S. Bozzini, C. Del Fante, M. Morosini, H. Berezhinskiy, S. Auner, E. Cattaneo, M. Della Zoppa, L. Pandolfi, R. Cacciatore, C. Perotti, K. Hötzenecker, P. Jaksch, A. Benazzo, F. Meloni.
Cells. 2022 Mar 25;11(7):1117. doi: 10.3390/cells11071117. PMID: 35406680
Neoadjuvant chemoradiotherapy is superior to chemotherapy alone in surgically treated stage III/N2 non-small-cell lung cancer: a retrospective single-center cohort study
K. Sinn, B. Mosleh, A. Steindl, S. Zöchbauer-Müller, U. Dieckmann, J. Widder, E. Steiner, W. Klepetko, K. Hötzenecker, V. Laszlo, B. Doeme, T. Klikovits, M. Hoda. ESMO Open. 2022 Apr;7(2):100466. doi: 10.1016/j.esmoop.2022.100466. Epub 2022 Apr 6. PMID: 35397435
Short-term and sustained clinical response following thymectomy in patients with myasthenia gravis
J. Rath, M. Taborsky, B. Moser, G. Zulehner, R. Weng, M. Krenn, H. Cetin, J. Matilla Sigüenza, L. Müllauer, F. Zimprich. Eur J Neurol. 2022 Aug;29(8):2453-2462. doi: 10.1111/ene.15362. Epub 2022 Apr 30. PMID: 35435305
Nationwide lung cancer screening with low-dose computed tomography: implementation and first results of the HUNCHEST screening program
A. Kerpel-Fronius, Z. Monostori, G. Kovacs, G. Ostoros, I. Horvath, D. Solymosi, O. Pipek, F. Szatmari, A. Kovacs, Z. Markoczy, L. Rojko, F. Renyi-Vamos, K. Hötzenecker, K. Bogos, Z. Megyesfalvi, B. Dome. Eur Radiol. 2022 Jul;32(7):4457-4467. doi: 10.1007/s00330-022-08589-7. Epub 2022 Mar 5. PMID: 35247089
Impact of Lung Function Decline on Mortality in Lung Transplant Recipients: Long-Term Results From the L-CsA-i Study for the Prevention of Bronchiolitis Obliterans Syndrome
N. Kneidinger, A. Ghiani, K. Milger, V. Monforte, C. Knoop, P. Jaksch, J. Parmar, P. Ussetti, A. Sole, J. Mueller-Quernheim, A. Voelp, J. Behr, C. Neurohr. Front Med (Lausanne). 2022 Jun 2:9:897581. doi: 10.3389/fmed.2022.897581. eCollection 2022. PMID: 35721046
Expression patterns and prognostic relevance of subtype-specific transcription factors in surgically resected small-cell lung cancer: an international multicenter study
Z. Megyesfalvi, N. Barany, A. Lantos, Z. Valkó, O. Pipek, C. Lang, A. Schwendenwein, F. Oberndorfer, S. Paku, B. Ferencz, K. Dezso, J. Fillinger, Z. Lohinai, J. Moldvay, G. Galffy, B. Szeitz, M. Rezeli, C. Rivard, F. Hirsch, L. Brcic, H. Popper, I. Kern, M. Kovacevic, J. Skarda, M. Mittak, G. Marko-Varga, K. Bogos, F. Renyi-Vamos, M. Hoda, T. Klikovits, K. Hötzenecker, K. Schelch, V. Laszlo, B. Dome. J Pathol. 2022 Aug;257(5):674-686. doi: 10.1002/path.5922. Epub 2022 May 25. PMID: 35489038
Lungs from polytrauma donors with significant chest trauma can be safely used for transplantation
S. Schwarz, N. Rahimi, D. Kifjak, F. Frommlet, A. Benazzo, P. Jaksch, W. Klepetko, K. Hötzenecker. J Thorac Cardiovasc Surg. 2022 May;163(5):1719-1731.e2. doi: 10.1016/j.jtcvs.2020.10.150. Epub 2020 Nov 27. PMID: 33451825
Lymphocyte-to-monocyte ratio is an independent prognostic factor in surgically treated small cell lung cancer: An international multicenter analysis. C. Lang, F. Egger, M. Hoda, A. Querner, B. Ferencz, V. Lungu, R. Szegedi, L. Bogyo, K. Torok, F. Oberndorfer, T. Klikovits, A. Schwendenwein, K. Boettiger, F. Renyi-Vamos, K. Hötzenecker, K. Schelch, Z. Megyesfalvi, B. Dome. Lung Cancer. 2022 Jul:169:40-46. doi: 10.1016/j.lungcan.2022.05.010. Epub 2022 May 18. PMID: 35643059
Metagenomic sequencing reveals time, host, and body compartment-specific viral dynamics after lung transplantation
S. Widder, I. Görzer, B. Friedel, N. Rahimi, S. Schwarz, P. Jaksch, S. Knapp, E. Puchhammer. Microbiome. 2022 Apr 23;10(1):66. doi: 10.1186/s40168-022-01244-9. PMID: 35459224
Immune Response after mRNA COVID-19 Vaccination in Lung Transplant Recipients: A 6-Month Follow-Up
S. Tobudic, A. Benazzo, M. Koblischke, L. Schneider, S. Blüml, F. Winkler, H. Schmidt, S. Vorlen, H. Haslacher, T. Perkmann, H. Burgmann, P. Jaksch, J. Aberle, S. Winkler. Vaccines (Basel). 2022 Jul 15;10(7):1130. doi: 10.3390/vaccines10071130. PMID: 35891294
Management of patients with SARS-CoV-2 infections with focus on patients with chronic lung diseases (as of 10 January 2022) Updated statement of the Austrian Society of Pneumology (ASP)
H. Olschewski, E. Eber, B. Bucher, K. Hackner, S. Handzhiev, K. Hötzenecker, M. Idzko, W. Klepetko, G. Kovacs, B. Lamprecht, J. Loeffler-Ragg, M. Meilinger, A. Mueller, C. Prior, O. Schindler, H. Taeubl, A. Zacharasiewicz, R. Zwick, B. Arns, J. Bolitschek, K. Cima, E. Gingrich, M. Hochmair, F. Horak, P. Jaksch, R. Kropfmueller, A. Pfleger, B. Puchner, C. Puelacher, P. Rodriguez, H. Salzer, P. Schenk, I. Stelzmueller, V. Strenger, M. Urban, M. Wagner, F. Wimberger, H. Flick. Wien Klin Wochenschr. 2022 May;134(9-10):399-419. doi: 10.1007/s00508-022-02018-x. Epub 2022 Apr 21. PMID: 35449467
Paediatric Airway Surgery - Indications and Techniques
T. Schweiger, M. Evermann, I. Roesner, D. Denk-Linnert, W. Klepetko, K. Hötzenecker. Laryngorhinootologie. 2023 Sep;102(9):652-657. doi: 10.1055/a-1985-1625. Epub 2023 May 22. PMID: 37216962
Short-Time Effect of Alemtuzumab Induction Therapy on B- and T-cell Subsets After Lung Transplantation
S. Auner, A. Cho, H. Berezhinskiy, G. Murakozy, G. Lang, S. Taghavi, W. Klepetko, T. Wekerle, K. Hötzenecker, P. Jaksch, A. Benazzo. The Journal of Heart and Lung Transplantation Volume 41, Issue 4, Supplement, April 2022, Pages S306-S307. https://doi.org/10.1016/j.healun.2022.01.759
Contrary to Persisting De-Novo DSA, Transient De-Novo DSAs After Lung Transplantation Do Not Constitute a Risk Factor for Patient and Graft Survival
A. Benazzo, A. Nechay, S. Auner, P. Böhm, S. Schwarz, T. Schweiger, G. Muraközy, S. Taghavi, W. Klepetko, K. Hötzenecker, P. Jaksch. The Journal of Heart and Lung Transplantation Volume 41, Issue 4, Supplement, April 2022, Page S157. https://doi.org/10.1016/j.healun.2022.01.373
Mechanisms of Action of Extracorporeal Photopheresis in the Control of BOS: Involvement of Circulating miRNAs
S. Bozzini, A. Benazzo, H. Berezhinskiy, S. Auner, C. Del Fante, L. Pandolfi, M. Morosini, C. Perotti, K. Hötzenecker, P. Jaksch, F. Meloni. Cells. 2022 Mar 25;11(7):1117. doi: 10.3390/cells11071117. PMID: 35406680
First Report of Daratumumab in Clinical Lung Transplantation
P. Jaksch, G. Muraközy, G. Fischer, K. Hötzenecker, A. Benazzo. The Journal of Heart and Lung Transplantation Volume 41, Issue 4, Supplement, April 2022, Page S533. https://doi.org/10.1016/j.healun.2022.01.1353
Lung transplantation in HIV patients
C. Rouzaud, C. Berastegui, C. Picard, R. Vos, L. Savale, X. Demant, A. Bertani, E. Verschuuren, P. Jaksch, A. Reed, L. Morlacchi, M. Reynaud-Gaubert, J. Gottlieb, J. Le Pavec. The Journal of Heart and Lung Transplantation Volume 41, Issue 4, Supplement, April 2022, Pages S531-S532. https://doi.org/10.1016/j.healun.2022.01.1349
Absolute Lymphocyte Count as a Prognostic Factor for Cytomegalovirus Infection After Heart Transplantation
A. Schöberl, A. Kaider, J. Gökler, A. Zuckermann. The Journal of Heart and Lung Transplantation Volume 41, Issue 4, Supplement, April 2022, Page S280. https://doi.org/10.1016/j.healun.2022.01.688
Gamma-Glutamyltransferase at the Time of Listing May Predict Irreversible Severe Cholangiopathy After Lung Transplantation for COVID19-ARDS
S. Schwarz, C. Lang, A. Benazzo, G. Muraközy, P. Jaksch, W. Klepetko, K. Hötzenecker
J Heart Lung Transplant. 2022 Apr; 41(4): S481–S482. Published online 2022 Apr 7. doi: 10.1016/j.healun.2022.01.1218. PMCID: PMC8988709
A long-term single center experience of chronic thromboembolic pulmonary hypertension
T. Hofbauer, L. Engel, B. Reil, C. Gerges, V. Seidl, A. Ondra¿ek, N. Skoro-Sajer, B. Moser, S. Taghavi, W. Klepetko, I. Lang. Wiener Klinische Wochenschrift
Comprehensive Profiling of Endothelial Cell Surface and Adhesion Molecules in Pulmonary Fibrosis
E. Fliesser, A. Birnhuber, L. Marsh, P. Böhm, K. Hötzenecker, G. Kovacs, H. Olschewski, M. Kreuter, M. Wygrecka, G. Kwapiszewska. American Journal of Respiratory and Critical Care Medicine 2022;205:A5239. https://doi.org/10.1164/ajrccm-conference.2022.205.1_MeetingAbstracts.A5239
Chronic thromboembolic pulmonary hypertension and left ventricular filling pressures
C. Gerges, A. Pistritto, M. Gerges, R. Friewald, T. Hofbauer, V. Hartig, V. Dannenberg, N. Skoro-Sajer, B. Moser, S. Taghavi, W. Klepetko, I. Lang. European Heart Journal, Volume 43, Issue Supplement_2, October 2022, ehac544.1911, https://doi.org/10.1093/eurheartj/ehac544.1911
Metagenomic sequencing reveals time, host, and body compartment-specific viral dynamics after lung transplantation
S. Widder, I. Görzer, B. Friedel, N. Rahimi, S. Schwarz, P. Jaksch, S. Knapp, E. Puchhammer. Microbiome. 2022 Apr 23;10(1):66. doi: 10.1186/s40168-022-01244-9. PMID: 35459224
Differential expression of circulating miRNAs after alemtuzumab induction therapy in lung transplantation
A. Benazzo, S. Bozzini, S. Auner, H. Berezhinskiy, M. Watzenböck, S. Schwarz, T. Schweiger, W. Klepetko, T. Wekerle, K. Hötzenecker, F. Meloni, P. Jaksch. Sci Rep. 2022 Apr 30;12(1):7072. doi: 10.1038/s41598-022-10866-w. PMID: 35490174
Lung Transplantation for Acute Respiratory Distress Syndrome
A. Bharat, K. Hötzenecker. Thorac Surg Clin. 2022 May;32(2):135-142. doi: 10.1016/j.thorsurg.2022.01.005. Epub 2022 Jan 31. PMID: 35512932
Malignant pleural mesothelioma nodules remodel their surroundings to vascularize and grow
I. Kovacs, E. Bugyik, K. Dezso, J. Tarnoki-Zach, E. Mehes, M. Gulyas, A. Czirok, E. Lang, M. Grusch, K. Schelch, B. Hegedus, I. Horvath, N. Barany, Z. Megyesfalvi, A. Tisza, Z. Lohinai, M. Hoda, K. Hötzenecker, F. Pezzella, S. Paku, V. Laszlo, B. Dome. Transl Lung Cancer Res. 2022 Jun;11(6):991-1008. doi: 10.21037/tlcr-21-828. PMID: 35832452
Lung Volume Reduction Followed by Lung Transplantation in Emphysema-A Multicenter Matched Analysis
A. Slama, L. Ceulemans, C. Hedderich, P. Böhm, J. Van Slambrouck, S. Schwarz, C. Vandervelde, M. Kamler, P. Jaksch, D. Van Raemdonck, K. Hötzenecker, C. Aigner. Transpl Int. 2022 Apr 14:35:10048. doi: 10.3389/ti.2022.10048. eCollection 2022. PMID: 35497884
Multimodality treatment of malignant pleural mesothelioma: evolving patient selection criteria using scores
S. Boeluekbas, N. Baldes, M. Hoda, M. Eberlein. Eur J Cardiothorac Surg. 2022 Jul 11;62(2):ezac153. doi: 10.1093/ejcts/ezac153. PMID: 35349643
Corrigendum to ‘Neoadjuvant chemoradiotherapy is superior to chemotherapy alone in surgically treated stage III/N2 non-small-cell lung cancer: a retrospective single-center cohort study’: [ESMO Open Volume 7, Issue 2, April 2022, 100466]
K. Sinn, B. Mosleh, A. Steindl, S. Zöchbauer-Müller, U. Dieckmann, J. Widder, E. Steiner, W. Klepetko, K. Hötzenecker, V. Laszlo, B. Dome, T. Klikovits, M. Hoda. ESMO Open. 2022 Jun;7(3):100523. doi: 10.1016/j.esmoop.2022.100523. Epub 2022 Jun 10. PMID: 35696745
Schwann cells contribute to keloid formation
M. Direder, T. Weiss, D. Copic, V. Vorstandlechner, M. Laggner, K. Pfisterer, C. Mildner, K. Klas, D. Bormann, W. Haslik, C. Radtke, M. Farlik-Födinger, L. Shaw, B. Golabi, E. Tschachler, K. Hötzenecker, H. Ankersmit, M. Mildner. Matrix Biol. 2022 Apr:108:55-76. doi: 10.1016/j.matbio.2022.03.001. Epub 2022 Mar 10. PMID: 35278628
Pleural diseases
L. Antoniewicz, M. Hoda, D. Gompelmann; Z Pneumologie 19, 234–244 (2022). https://doi.org/10.1007/s10405-022-00448-y
Alpha-Gal-specific humoral immune response and reported clinical consequence for cardiac valve replacement in patients below 65 years: moving beyond conjecture
D. Copic, D. Bormann, M. Direder, H. Ankersmit. Eur J Cardiothorac Surg. 2022 Jun 15;62(1):ezac227. doi: 10.1093/ejcts/ezac227. PMID: 35388903
Lung transplantation in HIV-positive patients: a European retrospective cohort study
C. Rouzaud, C. Berastegui, C. Picard, R. Vos, L. Savale, X. Demant, A. Bertani, E. Verschuuren, P. Jaksch, A. Reed, L. Morlacchi, M. Reynaud-Gaubert, O. Lortholary, E. Fadel, M. Humbert, J. Gottlieb, J. Le Pavec. Eur Respir J. 2022 Jul 13;60(1):2200189. doi: 10.1183/13993003.00189-2022. Print 2022 Jul. PMID: 35595318
The secretome of irradiated peripheral blood mononuclear cells attenuates activation of mast cells and basophils. M. Laggner, G. Sanchez Acosta, C. Kitzmüller, D. Copic, F. Gruber, L. Altenburger, V. Vorstandlechner, A. Gugerell, M. Direder, K. Klas, D. Bormann, A. Peterbauer, A. Shibuya, B. Bohle, H. Ankersmit, M. Mildner. EBioMedicine. 2022 Jul:81:104093. doi: 10.1016/j.ebiom.2022.104093. Epub 2022 Jun. 4. DOI: 10.1016/j.ebiom.2022.104093 PMID: 35671621
Duration of extracorporeal life support bridging delineates differences in the outcome between awake and sedated bridge-to-transplant patients
F. Ponholzer, S. Schwarz, P. Jaksch, A. Benazzo, D. Kifjak, K. Hötzenecker, T. Schweiger. Eur J Cardiothorac Surg. 2022 Aug 3;62(3):ezac363. doi: 10.1093/ejcts/ezac363. PMID: 35916716
Lung transplantation for acute respiratory distress syndrome: a retrospective European cohort study
J. Gottlieb, P. Lepper, C. Berastegui, B. Montull, A. Wald, J. Parmar, J. Magnusson, F. Schoenrath, T. Laisaar, S. Michel, H. Larsson, R. Vos, A. Haneya, T. Sandhaus, E. Verschuuren, J. le Pavec, J. Tikkanen, K. Hötzenecker. Eur Respir J. 2022 Jun 30;59(6):2102078. doi: 10.1183/13993003.02078-2021. Print 2022 Jun. PMID: 34824051
Does Myasthenia Gravis Affect Long-Term Survival in Thymic Carcinomas? An ESTS Database Analysis
F. Lococo, D. Nachira, M. Chiappetta, J. Evangelista, P. Falcoz, E. Ruffini, P. Van Schil, M. Scarci, J. Furak, F. Sollitto, F. Guerrera, L. Spaggiari, C. Aigner, L. Evangelia, A. Bille, B. Moser, P. Thomas, M. Liberman, S. Boubia, A. Campisi, L. Ampollini, A. Toker, A. Enyed, L. Voltolini, D. Van Raemdonck, S. Margaritora. Diagnostics (Basel). 2022 Jul 21;12(7):1764. doi: 10.3390/diagnostics12071764. PMID: 35885668
Tumour immune microenvironment in resected thymic carcinomas as a predictor of clinical outcome
G. Bocchialini, A. Schiefer, L. Müllauer, J. Thanner, J. Bauer, F. Thaler, M. Laggner, C. Veraar, W. Klepetko, K. Hötzenecker, J. Matilla Sigüenza, H. Ankersmit, B. Moser. Br J Cancer. 2022 Oct;127(6):1162-1171. doi: 10.1038/s41416-022-01875-7. Epub 2022 Jun 24. PMID: 35750748
The Effect of Paracrine Factors Released by Irradiated Peripheral Blood Mononuclear Cells on Neutrophil Extracellular Trap Formation
K. Klas, A. Ondracek, T. Hofbauer, A. Mangold, K. Pfisterer, M. Laggner, D. Copic, M. Direder, D. Bormann, H. Ankersmit, M. Mildner. Antioxidants (Basel). 2022 Aug 11;11(8):1559. doi: 10.3390/antiox11081559. PMID: 36009277
Human cytomegalovirus strain diversity and dynamics reveal the donor lung as a major contributor after transplantation
B. Külekci, S. Schwarz, N. Brait, N. Perkmann-Nagele, P. Jaksch, K. Hötzenecker, E. Puchhammer, I. Görzer. Virus Evol. 2022 Aug 24;8(2):veac076. doi: 10.1093/ve/veac076. eCollection 2022. PMID: 36128049
Paracrine Factors of Stressed Peripheral Blood Mononuclear Cells Activate Proangiogenic and Anti-Proteolytic Processes in Whole Blood Cells and Protect the Endothelial Barrier
D. Copic, M. Direder, K. Schossleitner, M. Laggner, K. Klas, D. Bormann, H. Ankersmit, M. Mildner. Pharmaceutics. 2022 Jul 30;14(8):1600. doi: 10.3390/pharmaceutics14081600. PMID: 36015226
The Antifibrotic Effects of Inhaled Treprostinil: An Emerging Option for ILD
M. Kolb, S. Orfanos, C. Lambers, K. Flaherty, A. Masters, L. Lancaster, A. Silverstein, S. Nathan. Adv Ther. 2022 Sep;39(9):3881-3895. doi: 10.1007/s12325-022-02229-8. Epub 2022 Jul 3. PMID: 35781186
Surgical resection of Masaoka stage III thymic epithelial tumours with great vessels involvement: a retrospective multicentric analysis from the European Society of Thoracic Surgeons thymic database
P. Mendogni, A. Toker, B. Moser, F. Trancho, C. Aigner, I. Bravio, N. Novoa, L. Molins, L. Costardi, L. Voltolini, N. Ardo, B. Verdonck, L. Ampollini, C. Zisis, V. Barmin, A. Enyedi, E. Ruffini, D. Van Raemdonck, P. Thomas, W. Weder, G. Rocco, A. Brunelli, F. Detterbeck, F. Venuta, P. Falcoz, D. Tosi, G. Bonitta, M. Nosotti. Eur J Cardiothorac Surg. 2022 Sep 2;62(4):ezac021. doi: 10.1093/ejcts/ezac021. PMID: 35084028
Commentary: Selection criteria for lung transplantation-is there room for individualization
P. Jaksch, K. Hötzenecker. J Thorac Cardiovasc Surg. 2022 Apr;163(4):1558-1559. doi: 10.1016/j.jtcvs.2020.10.119. Epub 2020 Nov 9. PMID: 33288236
Seminars AATS International Roundtable of Lung Transplantation for COVID-19
R. Ripley, G. Loor, A. Bharat, T. Machuca, M. Cypel, K. Hötzenecker. Semin Thorac Cardiovasc Surg. 2022 Autumn;34(3):1028-1039. doi: 10.1053/j.semtcvs.2022.05.012. Epub 2022 Jun 11. PMID: 35697136
Integrated Immunologic Monitoring in Solid Organ Transplantation: The Road Toward Torque Teno Virus-guided Immunosuppression
P. Jaksch, I. Görzer, E. Puchhammer, G. Bond. Transplantation. 2022 Oct 1;106(10):1940-1951. doi: 10.1097/TP.0000000000004153. Epub 2022 May 5. PMID: 35509090
EP07.02-001 Evaluation of FGF18 as a Contributing Factor in Malignant Pleural Mesothelioma Growth and Its Role as a Potential Biomarker
B. Mosleh, K. Schelch, T. Klikovits, K. Sinn, K. Hötzenecker, B. Dome, M. Jakopovic, M. Hoda, M. Grusch. Journal of Thoracic Oncology Volume 17, Issue 9, Supplement, September 2022, Pages S325-S326. https://doi.org/10.1016/j.jtho.2022.07.559
Mesothelioma-Associated Fibroblasts Enhance Mesothelioma Aggressiveness and Modulate Drug Response
A. Ries, D. Flehberger, K. Schelch, C. Pirker, M. Hoda, W. Berger, M. Grusch. Journal of Thoracic Oncology Volume 17, Issue 9, Supplement, September 2022, Page S319 DOI: 10.1016/j.jtho.2022.07.546
Cisplatin in Combination with Entinostat exerts Synergistic Antineoplastic Activity in Small Cell Lung Cancer. A. Schwendenwein, K. Boettiger, I. Kovacs, N. Barany, C. Lang, Z. Megyesfalvi, M. Grusch, C. Kowol, M. Rezeli, K. Hötzenecker, B. Dome, K. Schelch. Journal of Thoracic Oncology. Volume 17, Issue 9, Supplement, September 2022, https://doi.org/10.1016/j.jtho.2022.07.962
Impact Of Fibrinogen Levels and mGPS on Survival of Stage III/N2 NSCLC Patients Treated with Neoadjuvant Therapy and Radical Surgery. K. Sinn, B. Mosleh, M. Grusch, K. Hötzenecker, T. Klikovits, D. Gompelmann, M. Hoda. Journal of Thoracic Oncology; Volume 17Issue 9. doi:https://doi.org/10.1016/j.jtho.2022.07.490
Clinical Significance of MYC Family Members in Surgically Resected Limited-Stage Small Cell Lung Cancer: A Multicenter Study. C. Lang, A. Lantos, Z. Megyesfalvi, F. Oberndorfer, A. Schwendenwein, G. Timelthaler, B. Ferencz, J. Fillinger, M. Hoda, T. Klikovits, A. Querner, F. Egger, K. Boettiger, K. Hötzenecker, F. Renyi-Vamos, K. Schelch, B. Dome
Molecular Subtypes of Surgically Resected Small Cell Lung Cancer: Expression Pattern and Prognostic Relevance. Z. Megyesfalvi, N. Barany, A. Lantos, Z. Valko, O. Pipek, C. Lang, A. Schwendenwein, F. Oberndorfer, S. Paku, B. Ferencz, K. Dezso, J. Fillinger, Z. Lohinai, J. Moldvay, G. Galffy, M. Rezeli, C. Rivard, F. Hirsch, L. Brcic, H. Popper, I. Kern, M. Kovacevic, J. Skarda, M. Mittak, G. Marko-Varga, K. Bogos, F. Renyi-Vamos, M. Hoda, T. Klikovits, K. Hötzenecker, K. Schelch, V. Laszlo, B. Dome
In-depth proteomic analysis reveals unique subtype-specific signatures in human small-cell lung cancer. B. Szeitz, Z. Megyesfalvi, N. Woldmar, Z. Valkó, A. Schwendenwein, N. Barany, S. Paku, V. Laszlo, H. Kiss, E. Bugyik, C. Lang, A. Szasz, L. Pizzatti, K. Bogos, M. Hoda, K. Hötzenecker, G. Marko-Varga, P. Horvatovich, B. Dome, K. Schelch, M. Rezeli
Impairment of the NKT-STAT1-CXCL9 Axis Contributes to Vessel Fibrosis in Pulmonary Hypertension Caused by Lung Fibrosis. K. Jandl, L. Marsh, A. Mutgan, S. Crnkovic, F. Valzano, D. Zabini, J. Hoffmann, V. Foris, E. Gschwandtner, W. Klepetko, H. Prosch, H. Flick, L. Brcic, I. Kern, A. Heinemann, H. Olschewski, G. Kovacs, G. Kwapiszewska
Follistatin-like 1 and Biomarkers of Neutrophil Activation Are Associated with Poor Short-Term Outcome after Lung Transplantation on VA-ECMO. C. Veraar, E. Kirschner, S. Schwarz, P. Jaksch, K. Hötzenecker, E. Tschernko, M. Dworschak, H. Ankersmit, B. Moser
Perioperative Management of Patients With Myasthenia Gravis Undergoing Robotic-Assisted Thymectomy-A Retrospective Analysis and Clinical Evaluation. G. Scheriau, R. Weng, A. Laßnigg, M. Maleczek, F. Zimprich, J. Matilla Sigüenza, B. Moser, M. Bernardi
Subtype-specific Hypersensitivity to Oxidative Phosphorylation Inhibition in Small Cell Lung Cancer. K. Boettiger, A. Schwendenwein, C. Lang, Z. Megyesfalvi, K. Hötzenecker, M. Rezeli, B. Dome, K. Schelch
PD-L1 Expression in Biopsies and Surgical Specimens of Lung Cancer: Impact of Biopsy Methods and Neoadjuvant Therapy. M. Hoda, K. Sinn, J. Brugger, D. Bernitzky, B. Mosleh, H. Prosch, S. Geleff, K. Hötzenecker, M. Idzko, D. Gompelmann
Antineoplastic efficacy profiles of avapritinib and nintedanib in KIT D816V+ systemic mastocytosis: a preclinical study. L. Degenfeld-Schonburg, S. Gamperl, G. Stefanzl, A. Schruef, I. Sadovnik, K. Bauer, D. Smiljkovic, G. Eisenwort, B. Peter, G. Greiner, E. Hadzijusufovic, J. Schwaab, W. Sperr, G. Hörmann, S. Kopanja, Z. Szépfalusi, K. Hötzenecker, P. Jaksch, A. Reiter, M. Arock, P. Valent
Mechanical aortic valve prostheses offer a survival benefit in 50-65 year olds: AUTHEARTVISIT study D. Traxler-Weidenauer, P. Krotka, M. Laggner, M. Mildner, A. Graf, B. Reichardt, R. Wendt, J. Auer, B. Moser, J. Mascherbauer, H. Ankersmit
Brain-only oligometastatic cancer patients present with longer overall survival than patients with extracranial involvement. A. Steindl, A. Ahmadi, G. Moser, B. Gatterbauer, U. Dieckmann, G. Widhalm, M. Hoda, M. Preusser, A. Bergmeister-Berghoff
TNF induction in essential for oncolytic influenza A virus induced cancer regression and tumor associated macrophage repolarization. J. Homola, J. Kabiljo, A. Theophil, N. Hartman, I. Kovacs, J. Karall, K. Lechner, C. Klicka, J. Längle, M. Fabits, V. Atanasova, B. Dome, H. Dolznig, G. Egger, H. Walczak, M. Bergmann
Combining STING-agonist with radiotherapy remodels tumor immune microenvironment in human malignant pleural effusions. R. Zirnbauer, D. Ammon, B. Mosleh, M. Hoda, M. Fabits, J. Längle, M. Bergmann
Validation of lymphocyte-to-monocyte ratio as an independent prognostic factor in surgically treated small cell lung cancer: an international multicenter analysis. F. Egger, Z. Megyesfalvi, M. Hoda, A. Querner, B. Ferencz, V. Lungu, R. Szegedi, L. Bogyo, K. Torok, F. Oberndorfer, T. Klikovits, A. Schwendenwein, K. Boettiger, F. Renyi-Vamos, K. Hötzenecker, K. Schelch, B. Dome, C. Lang. Wiener Klinische Wochenschrift
Pre- and postoperative functional outcome in patients receiving laryngotracheal surgery. M. Evermann, I. Roesner, D. Denk-Linnert, W. Klepetko, K. Hötzenecker, T. Schweiger. Wiener Klinische Wochenschrift
Children with congenital heart defects are growing up - a new challenge in heart-lung transplantation. Z. Kovacs. Wiener Klinische Wochenschrift
Evaluation of CD47 and PD-L1 protein expression patterns reveals therapeutic and prognostic implications in small cell lung cancer. C. Lang, A. Lantos, Z. Megyesfalvi, F. Egger, M. Hoda, T. Klikovits, F. Oberndorfer, G. Timelthaler, B. Ferencz, J. Fillinger, A. Schwendenwein, A. Querner, K. Boettiger, F. Renyi-Vamos, K. Hötzenecker, K. Schelch, M. Rezeli, G. Marko-Varga, B. Dome. Wiener Klinische Wochenschrift
FGF18 is significantly decreased in the plasma of mesothelioma patients but not linked to prognosis. B. Mosleh, K. Schelch, T. Mohr, Y. Dong, K. Sinn, A. Ries, W. Berger, B. Grasl-Kraupp, K. Hötzenecker, V. Laszlo, B. Dome, B. Hegedüs, M. Jakopovic, T. Klikovits, M. Hoda, M. Grusch. Wiener Klinische Wochenschrift
Expression and prognostic value of thyroid-hormone-associated proteins in surgically resected small cell lung cancer: a pilot study. A. Querner, C. Lang, A. Lantos, Z. Megyesfalvi, F. Egger, M. Hoda, E. Gurnhofer, B. Ferencz, J. Fillinger, A. Schwendenwein, K. Boettiger, F. Renyi-Vamos, K. Hötzenecker, K. Schelch, B. Dome, L. Kenner. Wiener Klinische Wochenschrift
Insertion of single site dual-lumen catheters via alternative venous access for extra corporal membrane oxygenation. A. Schöberl, K. Hötzenecker, D. Staudacher, M. Cypel, M. Kawashima, C. Fisher, T. Schweiger. Wiener Klinische Wochenschrift
Remodeling of pulmonary arteries, airways and parenchyma in end-stage COPD patients with severe pulmonary hypertension. K. Zeder, L. Marsh, A. Avian, L. Brcic, A. Birnhuber, P. Douschan, V. Foris, T. Sassmann, K. Hötzenecker, P. Böhm, G. Kwapiszewska, H. Olschewski, G. Kovacs. Wiener Klinische Wochenschrift
Single-cell transcriptomics reveals skewed cellular communication and phenotypic shift in pulmonary artery remodeling. S. Crnkovic, F. Valzano, E. Fliesser, J. Gindlhuber, H. Puthenparampil, M. Basil, M. Morley, J. Katzen, E. Gschwandtner, W. Klepetko, E. Cantu, H. Wolinski, H. Olschewski, J. Lindenmann, Y. Zhao, E. Morrisey, L. Marsh, G. Kwapiszewska
ISHLT consensus statement: Perioperative management of patients with pulmonary hypertension and right heart failure undergoing surgery. D. McGlothlin, J. Granton, W. Klepetko, M. Beghetti, E. Rosenzweig, P. Corris, E. Horn, M. Kanwar, K. Mcrae, A. Roman, R. Tedford, R. Badagliacca, S. Bartolome, R. Benza, M. Caccamo, R. Cogswell, C. Dewachter, L. Donahoe, E. Fadel, H. Farber, J. Feinstein, V. Franco, R. Frantz, M. Gatzoulis, C. Goh, M. Guazzi, G. Hansmann, S. Hastings, P. Heerdt, A. Hemnes, A. Herpain, C. Hsu, K. Kerr, N. Kolaitis, J. Kukreja, M. Madani, S. McCluskey, M. McCulloch, B. Moser, M. Navaratnam, G. Radegran, C. Reimer, L. Savale, O. Shlobin, J. Svetlichnaya, K. Swetz, J. Tashjian, T. Thenappan, C. Vizza, S. West, W. Zuckerman, A. Zuckermann, T. De Marco
Extracorporeal life support as a bridge to lung transplantation: Where are we now? C. Patterson, A. Shah, J. Rabin, L. DiChiacchio, M. Cypel, K. Hötzenecker, P. Catarino, C. Lau.
Gamma-glutamyltransferase is a strong predictor of secondary sclerosing cholangitis after lung transplantation for COVID-19 ARDS. S. Schwarz, C. Lang, M. Harlander, T. Stupnik, J. Van Slambrouck, L. Ceulemans, F. Ius, J. Gottlieb, S. Kuhnert, M. Hecker, C. Aigner, N. Kneidinger, E. Verschuuren, J. Smits, E. Tschernko, E. Schaden, P. Faybik, K. Markstaller, M. Trauner, P. Jaksch, K. Hötzenecker
Functional outcome after single-stage laryngotracheal reconstruction with rib cartilage grafting. T. Schweiger, I. Roesner, I. De Faria Soares Rodrigues, M. Evermann, A. Frick, D. Denk-Linnert, W. Klepetko, K. Hötzenecker
Unilateral acute lung injury in pig: a promising animal model. J. Geilen, M. Kainz, B. Zapletal, S. Geleff, W. Wisser, B. Bohle, T. Schweiger, M. Schultz, E. Tschernko.
Clinical relevance of lung transplantation for COVID-19 ARDS: a nationwide study. C. Lang, V. Ritschl, F. Augustin, G. Lang, B. Moser, S. Taghavi, G. Muraközy, C. Lambers, H. Flick, M. Koestenberger, R. Brooks, T. Muhr, J. Knotzer, D. Mydza, M. Kaufmann, T. Staudinger, C. Zauner, C. Krenn, E. Schaden, A. Bacher, B. Rössler, P. Faybik, E. Tschernko, M. Anwar, K. Markstaller, D. Honefer, T. Stamm, P. Jaksch, K. Hötzenecker
Cervical Repair of Iatrogenic Tracheobronchial Injury by Tracheal T-Incision. M. Evermann, I. Roesner, D. Denk-Linnert, S. Taghavi, W. Klepetko, K. Hötzenecker, T. Schweiger
Impact of fibrinogen levels and modified Glasgow prognostic score on survival of stage III/N2 non-small cell lung cancer patients treated with neoadjuvant therapy and radical resection.K. Sinn, B. Mosleh, M. Grusch, W. Klepetko, K. Hötzenecker, T. Klikovits, D. Gompelmann, M. Hoda
Trabectedin Is Active against Two Novel, Patient-Derived Solitary Fibrous Pleural Tumor Cell Lines and Synergizes with Ponatinib. B. Ghanim, D. Baier, C. Pirker, L. Müllauer, K. Sinn, G. Lang, K. Hötzenecker, W. Berger
The American Association for Thoracic Surgery (AATS) 2022 Expert Consensus Document: The use of mechanical circulatory support in lung transplantation. M. Hartwig, V. van Berkel, A. Bharat, M. Cypel, H. Date, M. Erasmus, K. Hötzenecker, W. Klepetko, Z. Kon, J. Kukreja, T. Machuca, K. McCurry, O. Mercier, I. Opitz, V. Puri, D. Van Raemdonck
Completion Pneumonectomy for Second Primary/Primary Lung Cancer and Local Recurrence Lung Cancer. N. Miyahara, K. Nii, A. Benazzo, A. Iwasaki, W. Klepetko, K. Hötzenecker
A Dual-Lumen Extracorporeal Membrane Oxygenation Cannulation Technique Using a Mobile X-Ray Device. T. Schweiger, F. Ponholzer, D. Kifjak, S. Schwarz, A. Benazzo, G. Lang, E. Tschernko, K. Markstaller, K. Hötzenecker.
Clinical and prognostic implications of CD47 and PD-L1 expression in surgically resected small-cell lung cancer. C. Lang, A. Lantos, Z. Megyesfalvi, F. Egger, M. Hoda, B. Mosleh, T. Klikovits, F. Oberndorfer, G. Timelthaler, B. Ferencz, J. Fillinger, A. Schwendenwein, A. Querner, K. Boettiger, F. Renyi-Vamos, K. Hötzenecker, V. Laszlo, K. Schelch, B. Dome.
Lung transplantation for interstitial lung disease in idiopathic inflammatory myositis: A cohort study A. Riviere, C. Picard, C. Berastegui, V. Mora, V. Bunel, L. Godinas, E. Salvaterra, V. Rossetti, L. Savale, D. Israel-Biet, X. Demant, J. Bermudez, F. Meloni, P. Jaksch, J. Magnusson, L. Beaumont, M. Perch, J. Mornex, C. Knoop, J. Aubert, B. Hervier, H. Nunes, M. Humbert, J. Gottlieb, Y. Uzunhan, J. Le Pavec
Commentary: Say yes to NO! A. Benazzo, K. Hötzenecker
Commentary: Post-COVID-19 acute respiratory distress syndrome and post-COVID-19 fibrosis-the new kids in town. T. Schweiger, K. Hötzenecker.
Study design and rationale of the pAtients pResenTing with cOngenital heaRt dIseAse Register (ARTORIA-R). C. Sinning, E. Zengin, G. Diller, F. Onorati, M. Castel, T. Petit, Y. Chen, M. Lo Rito, C. Chiarello, R. Guillemain, K. Nubret-Le Coniat, C. Magnussen, D. Knappe, P. Becher, B. Schrage, J. Smits, A. Metzner, C. Knosalla, F. Schoenrath, O. Miera, M. Cho, A. Bernhardt, J. Weimann, A. Gossling, A. Terzi, A. Amodeo, S. Alfieri, E. Angeli, L. Ragni, C. Napoleone, G. Gerosa, N. Pradegan, I. Rodrigus, J. Dumfarth, M. de Pauw, K. Francois, O. Van Caenegem, A. Ancion, J. Van Cleemput, D. Milicic, A. Moza, P. Schenker, J. Thul, M. Steinmetz, G. Warnecke, F. Ius, S. Freyt, M. Avsar, T. Sandhaus, A. Haneya, S. Eifert, D. Saeed, M. Borger, H. Welp, L. Ablonczy, B. Schmack, A. Ruhparwar, S. Naito, X. Hua, N. Fluschnik, M. Nies, L. Keil, J. Senftinger, D. Ismaili, S. Kany, D. Csengeri, M. Cardillo, A. Oliveti, G. Faggian, R. Dorent, C. Jasseron, A. Blanco, J. Marquez, R. Lopez-Vilella, A. Garcia-Alvarez, M. Lopez, A. Rocafort, O. Fernandez, R. Prieto-Arevalo, E. Zatarain-Nicolas, K. Blanchart, A. Boignard, P. Battistella, S. Guendouz, L. Houyel, M. Para, E. Flecher, A. Gay, E. Epailly, C. Dambrin, K. Lam, C. Ka-lai, Y. Cho, J. Choi, J. Kim, L. Coats, D. Crossland, L. Mumford, S. Hakmi, C. Sivathasan, L. Fabritz, S. Schubert, J. Gummert, M. Huebler, P. Jaksch, A. Zuckermann, G. Laufer, H. Baumgartner, A. Giamberti, H. Reichenspurner, P. Kirchhof
Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile. H. Rossiter, D. Copic, M. Direder, F. Gruber, S. Zoratto, M. Marchetti-Deschmann, C. Kremslehner, M. Sochorova, I. Nagelreiter, V. Mlitz, M. Buchberger, B. Lengauer, B. Golabi, S. Sukseree, M. Mildner, L. Eckhart, E. Tschachler
Transcripts associated with chronic lung allograft dysfunction in transbronchial biopsies of lung transplants. M. Parkes, K. Halloran, A. Hirji, S. Pon, J. Weinkauf, I. Timofte, G. Snell, G. Westall, J. Havlin, R. Lischke, A. Zajacova, R. Hachem, D. Kreisel, D. Levine, B. Kubisa, M. Piotrowska, S. Juvet, S. Keshavjee, P. Jaksch, W. Klepetko, P. Halloran
The Roles of S100A4 and the EGF/EGFR Signaling Axis in Pulmonary Hypertension with Right Ventricular Hypertrophy. M. Laggner, P. Hacker, F. Oberndorfer, J. Bauer, T. Raunegger, C. Gerges, T. Szerafin, J. Thanner, I. Lang, N. Skoro-Sajer, H. Ankersmit, B. Moser
Difficulties in the differential diagnosis of large solitary pulmonary cysts. A. Frick, H. Ankersmit, I. Simonitsch-Klupp, K. Hötzenecker.
The transcriptional profile of keloidal Schwann cells. M. Direder, M. Wielscher, T. Weiss, M. Laggner, D. Copic, K. Klas, D. Bormann, V. Vorstandlechner, E. Tschachler, H. Ankersmit, M. Mildner
Commentary: Why a routine venoarterial extracorporeal membrane oxygenation support strategy is a good idea in lung transplantation. A. Andreasson, K. Hötzenecker
Prioritizing direct heart procurement in organ donors after circulatory death does not jeopardize lung transplant outcomes. S. Schwarz, J. Gökler, R. Moayedifar, C. Atteneder, G. Bocchialini, A. Benazzo, T. Schweiger, P. Jaksch, A. Zuckermann, A. Aliabadi-Zuckermann, K. Hötzenecker
The influence of body mass index and smoking on the age of onset of menopause in women in Bosnia and Herzegovina: a cross-sectional multicentric study. M. Rizvanovic, Z. Begic, L. Kameric, A. Cerovac, S. Rizvanovic, M. Begic, D. Habek
Schwann cells - an unexpected key player in keloid formation. M. Direder, T. Weiss, D. Copic, V. Vorstandlechner, K. Klas, M. Laggner, M. Wielscher, D. Bormann, H. Ankersmit, M. Mildner
End-stage COPD patients with severe pulmonary hypertension have less airspace enlargement in histologic samples of explanted lungs. K. Zeder, L. Marsh, A. Avian, L. Brcic, A. Birnhuber, P. Douschan, V. Foris, T. Sassmann, P. Böhm, K. Hötzenecker, G. Kwapiszewska, H. Olschewski, G. Kovacs
The ephrin-b2/EphB4 guidance system in pulmonary artery smooth muscle cells plays a central role in adult vascular remodeling. S. Rittchen, S. Crnkovic, K. Jandl, D. Zabini, A. Mutgan, P. Böhm, K. Hötzenecker, W. Toller, C. Veith, A. Heinemann, R. Schermuly, A. Olschewski, L. Marsh, G. Kwapiszewska
Subtype-specific transcription factors are clinically relevant and show distinct therapeutic vulnerabilities in human small cell lung cancer. C. Lang, Z. Megyesfalvi, B. Szeitz, A. Lantos, N. Woldmar, Z. Valkó, A. Schwendenwein, F. Oberndorfer, N. Barany, S. Paku, V. Laszlo, H. Kiss, E. Bugyik, B. Ferencz, K. Dezso, Z. Lohinai, J. Moldvay, J. Fillinger, G. Galffy, C. Rivard, F. Hirsch, L. Brcic, H. Popper, I. Kern, M. Kovacevic, J. Skarda, M. Mittak, A. Szasz, L. Pizzatti, K. Bogos, M. Hoda, K. Hötzenecker, G. Marko-Varga, P. Horvatovics, F. Renyi-Vamos, T. Klikovits, K. Schelch, M. Rezeli, B. Dome
Improvement of risk in patients with severe chronic thromboembolic pulmonary hypertension after 24weeks treatment with subcutaneous treprostinil. P. Jansa, R. Sadushi-Kolici, G. Kopec, N. Skoro-Sajer, M. Halank, I. Simkova, R. Steringer-Mascherbauer, B. Salobir, W. Klepetko, J. Lindner, I. Lang
Correlation of PD-L1 expression on tumour cells between diagnostic biopsies and surgical specimens of lung cancer in real life with respect to biopsy techniques and neoadjuvant treatment. D. Gompelmann, K. Sinn, J. Brugger, D. Bernitzky, B. Mosleh, H. Prosch, S. Geleff, A. Blessing, A. Tiefenbacher, K. Hötzenecker, M. Idzko, M. Hoda
Chronic thromboembolic pulmonary hypertension and left ventricular filling pressures. C. Gerges, A. Pistritto, M. Gerges, R. Friewald, T. Hofbauer, V. Hartig, V. Dannenberg, N. Skoro-Sajer, B. Moser, S. Taghavi, W. Klepetko, I. Lang
Involvement of miRNAs as a response to extracorporeal photopheresis in the control of bronchiolitis obliterans syndrome. S. Bozzini, C. Del Fante, M. Morosini, C. Bagnera, H. Berezhinskiy, S. Auner, L. Pandolfi, M. Della Zoppa, C. Perotti, K. Hötzenecker, P. Jaksch, A. Benazzo, F. Meloni
Validation of bedside ultrasound to predict lumbar muscle area in the computed tomography in 200 non-critically ill patients: The USVALID prospective study. A. Fischer, A. Hertwig, R. Hahn, M. Anwar, T. Siebenrock, M. Pesta, K. Liebau, I. Timmermann, J. Brugger, M. Posch, H. Ringl, D. Tamandl, D. Roth, T. Staudinger, P. Schellongowski, I. Lang, M. Gottsauner-Wolf, G. Heinz, R. Oberbauer, M. Trauner, S. Shariat, K. Sahora, G. Laufer, S. Taghavi, C. Radtke, B. Rössler, A. Bacher, P. Faybik, R. Ullrich, W. Plöchl, G. Ihra, B. Steinlechner, E. Tschernko, J. Hiesmayr
Larger pulmonary artery to ascending aorta ratios are associated with decreased survival of patients undergoing pulmonary endarterectomy.. P. Böhm, S. Schwarz, J. Thanner, C. Veraar, M. Gerges, C. Gerges, I. Lang, P. Apfaltrer, H. Prosch, S. Taghavi, W. Klepetko, H. Ankersmit, B. Moser
Extracorporeal life support as a bridge to pulmonary retransplantation: prognostic factors for survival in a multicentre cohort analysis.
Inci I, Ehrsam JP, Van Raemdonck D, Ceulemans LJ, Krüger T, Koutsokera A, Schiavon M, Faccioli E, Nosotti M, Rosso L, D'Ovidio F, Leiva-Juarez M, Aigner C, Slama A, Saleh W, Alkattan KM, Thomas PA, Brioude G, Benazzo A, Hoetzenecker K.Eur J Cardiothorac Surg. 2021 Dec 22:ezab514. doi: 10.1093/ejcts/ezab514. Online ahead of print.PMID: 34935039
Mechanical aortic valve prostheses offer a survival benefit in 50-65 year olds: AUTHEARTVISIT study.
Traxler D, Krotka P, Laggner M, Mildner M, Graf A, Reichardt B, Wendt R, Auer J, Moser B, Mascherbauer J, Ankersmit HJ.Eur J Clin Invest. 2021 Dec 21:e13736. doi: 10.1111/eci.13736. Online ahead of print.PMID: 34932232
Commentary: Why a routine venoarterial extracorporeal membrane oxygenation support strategy is a good idea in lung transplantation.
Andreasson A, Hoetzenecker K.J Thorac Cardiovasc Surg. 2021 Dec 8:S0022-5223(21)01729-3. doi: 10.1016/j.jtcvs.2021.12.008. Online ahead of print.PMID: 34930581
Discussion.
Klepetko W.J Thorac Cardiovasc Surg. 2021 Dec 9:S0022-5223(21)01636-6. doi: 10.1016/j.jtcvs.2021.08.091. Online ahead of print.PMID: 34895725
Transcripts associated with chronic lung allograft dysfunction in transbronchial biopsies of lung transplants.
Parkes MD, Halloran K, Hirji A, Pon S, Weinkauf J, Timofte IL, Snell GI, Westall GP, Havlin J, Lischke R, Zajacová A, Hachem R, Kreisel D, Levine D, Kubisa B, Piotrowska M, Juvet S, Keshavjee S, Jaksch P, Klepetko W, Halloran PF.Am J Transplant. 2021 Nov 30. doi: 10.1111/ajt.16895. Online ahead of print.PMID: 34850543
Clinical Relevance of Elevated Soluble ST2, HSP27 and 20S Proteasome at Hospital Admission in Patients with COVID-19.
Wendt R, Lingitz MT, Laggner M, Mildner M, Traxler D, Graf A, Krotka P, Moser B, Hoetzenecker K, Kalbitz S, Lübbert C, Beige J, Ankersmit HJ.Biology (Basel). 2021 Nov 15;10(11):1186. doi: 10.3390/biology10111186.PMID: 34827178
Lung transplantation for acute respiratory distress syndrome - a retrospective European Cohort Study.
Gottlieb J, Lepper PM, Berastegui C, Montull B, Wald A, Parmar J, Magnusson JM, Schönrath F, Laisaar T, Michel S, Larsson H, Vos R, Haneya A, Sandhaus T, Verschuuren E, le Pavec J, Tikkanen J, Hoetzenecker K.Eur Respir J. 2021 Nov 25:2102078. doi: 10.1183/13993003.02078-2021. Online ahead of print.PMID: 34824051
Gut microbiome functionality might be associated with exercise tolerance and recurrence of resected early-stage lung cancer patients.
Marfil-Sánchez A, Seelbinder B, Ni Y, Varga J, Berta J, Hollosi V, Dome B, Megyesfalvi Z, Dulka E, Galffy G, Weiss GJ, Panagiotou G, Lohinai Z.PLoS One. 2021 Nov 18;16(11):e0259898. doi: 10.1371/journal.pone.0259898. eCollection 2021.PMID: 34793492
Transcriptional Differences in Lipid-Metabolizing Enzymes in Murine Sebocytes Derived from Sebaceous Glands of the Skin and Preputial Glands.
Klas K, Copic D, Direder M, Laggner M, Prucksamas PS, Gruber F, Ankersmit HJ, Mildner M.Int J Mol Sci. 2021 Oct 27;22(21):11631. doi: 10.3390/ijms222111631.PMID: 34769061
Outcomes with alemtuzumab induction therapy in lung transplantation: a comprehensive large-scale single-center analysis.
Benazzo A, Auner S, Boehm PM, Morscher A, Schwarz S, Vidmar B, Dzubur F, Schweiger T, Hoda AM, Moser B, Matilla JR, Muraközy G, Lang G, Taghavi S, Klepetko W, Hoetzenecker K, Jaksch P.Transpl Int. 2021 Dec;34(12):2633-2643. doi: 10.1111/tri.14153. Epub 2021 Nov 16.PMID: 34738249
Difficulties in the differential diagnosis of large solitary pulmonary cysts.
Frick AE, Ankersmit HJ, Simonitsch-Klupp I, Hoetzenecker K.Interact Cardiovasc Thorac Surg. 2021 Oct 30:ivab292. doi: 10.1093/icvts/ivab292. Online ahead of print.PMID: 34718600
The serine proteases dipeptidyl-peptidase 4 and urokinase are key molecules in human and mouse scar formation.
'Vorstandlechner V, Laggner M, Copic D, Klas K, Direder M, Chen Y, Golabi B, Haslik W, Radtke C, Tschachler E, Hötzenecker K, Ankersmit HJ, Mildner M.Nat Commun. 2021 Oct 29;12(1):6242. doi: 10.1038/s41467-021-26495-2.PMID: 34716325
Bone-Specific Metastasis Pattern of Advanced-Stage Lung Adenocarcinoma According to the Localization of the Primary Tumor.
Radeczky P, Moldvay J, Fillinger J, Szeitz B, Ferencz B, Boettiger K, Rezeli M, Bogos K, Renyi-Vamos F, Hoetzenecker K, Hegedus B, Megyesfalvi Z, Dome B.Pathol Oncol Res. 2021 Sep 23;27:1609926. doi: 10.3389/pore.2021.1609926. eCollection 2021.PMID: 34629961
[Heterogeneity of small cell lung cancer: biological and clinicopathological implications].
Megyesfalvi Z, Bárány N, Valkó Z, Bugyik E, Paku S, Berta J, Lantos A, Fillinger J, Moldvay J, Bogos K, Rezeli M, Gálffy G, Lang C, Lohinai Z, Hécz R, Lovas T, Rényi-Vámos F, László V, Döme B.Magy Onkol. 2020 Sep 23;64(3):243-255. Epub 2020 Aug 9.PMID: 34608895
A randomized controlled trial of liposomal cyclosporine A for inhalation in the prevention of bronchiolitis obliterans syndrome following lung transplantation.
Neurohr C, Kneidinger N, Ghiani A, Monforte V, Knoop C, Jaksch P, Parmar J, Ussetti P, Sole A, Müller-Quernheim J, Kessler R, Wirtz H, Boerner G, Denk O, Prante Fernandes S, Behr J.Am J Transplant. 2022 Jan;22(1):222-229. doi: 10.1111/ajt.16858. Epub 2021 Oct 18.PMID: 34587371
Clinical relevance of circulating activin A and follistatin in small cell lung cancer.
Barany N, Rozsas A, Megyesfalvi Z, Grusch M, Hegedus B, Lang C, Boettiger K, Schwendenwein A, Tisza A, Renyi-Vamos F, Schelch K, Hoetzenecker K, Hoda MA, Paku S, Laszlo V, Dome B.Lung Cancer. 2021 Nov;161:128-135. doi: 10.1016/j.lungcan.2021.09.008. Epub 2021 Sep 20.PMID: 34583221
Oncofetal Chondroitin Sulfate Is a Highly Expressed Therapeutic Target in Non-Small Cell Lung Cancer.
Oo HZ, Lohinai Z, Khazamipour N, Lo J, Kumar G, Pihl J, Adomat H, Nabavi N, Behmanesh H, Zhai B, Dagil R, Choudhary S, Gustavsson T, Clausen TM, Esko JD, Allen JW, Thompson MA, Tran NL, Moldvay J, Dome B, Salanti A, Al-Nakouzi N, Weiss GJ, Daugaard M.Cancers (Basel). 2021 Sep 6;13(17):4489. doi: 10.3390/cancers13174489.PMID: 34503301
RGS5 Determines Neutrophil Migration in the Acute Inflammatory Phase of Bleomycin-Induced Lung Injury.
Sharma N, Nagaraj C, Nagy BM, Marsh LM, Bordag N, Zabini D, Wygrecka M, Klepetko W, Gschwandtner E, Genové G, Heinemann A, Weir EK, Kwapiszewska G, Olschewski H, Olschewski A.Int J Mol Sci. 2021 Aug 28;22(17):9342. doi: 10.3390/ijms22179342.PMID: 34502263
ISHLT consensus document on lung transplantation in patients with connective tissue disease: Part III: Pharmacology, medical and surgical management of post-transplant extrapulmonary conditions statements.
Crespo MM, Claridge T, Domsic RT, Hartwig M, Kukreja J, Stratton K, Chan KM, Molina M, Ging P, Cochrane A, Hoetzenecker K, Ahmad U, Kapnadak S, Timofte I, Verleden G, Lyu D, Quddus S, Davis N, Porteous M, Mallea J, Perch M, Distler O, Highland K, Magnusson J, Vos R, Glanville AR.J Heart Lung Transplant. 2021 Nov;40(11):1279-1300. doi: 10.1016/j.healun.2021.07.013. Epub 2021 Jul 31.PMID: 34474940
Human pegivirus 1 infection in lung transplant recipients: Prevalence, clinical relevance and kinetics of viral replication under immunosuppressive therapy.
Graninger M, Aberle S, Görzer I, Jaksch P, Puchhammer-Stöckl E.J Clin Virol. 2021 Oct;143:104937. doi: 10.1016/j.jcv.2021.104937. Epub 2021 Aug 14.PMID: 34416522
Corrigendum to 'Thymomectomy plus total thymectomy versus simple thymomectomy for early-stage thymoma without myasthenia gravis: a European Society of Thoracic Surgeons Thymic Working Group Study'.
Guerrera F, Falcoz PE, Moser B, van Raemdonck D, Bille A, Toker A, Spaggiari L, Ampollini L, Filippini C, Thomas PA, Verdonck B, Mendogni P, Aigner C, Voltolini L, Novoa N, Patella M, Mantovani S, Bravio IG, Zisis C, Guirao A, Londero F, Congregado M, Rocco G, Pont BD, Martucci N, Esch M, Brunelli A, Detterbeck FC, Venuta F, Weder W, Ruffini E; European Society of Thoracic Surgeons (ESTS) Thymic Working Group Participating Centers:, Klepetko W, Olland A, DuPont B, Nonaka D, Ozkan B, Lo Iacono G, Braggio C, Filosso PL, Brioude G, van Schil P, Nosotti M, Valdivia D, Bongiolatti S, Inci I, Dimitra R, Sànchez D, Grossi W, Moreno-Merino S, Teschner M.Eur J Cardiothorac Surg. 2021 Oct 22;60(4):1009-1010. doi: 10.1093/ejcts/ezab316.PMID: 34378012
Analysis and Fine Specificity of the HCMV-Specific Cell-Free and Cell-Associated Antibody-Dependent Cellular Phagocytosis (ADCP) Responses in Lung Transplant Recipients.
Eberhard S, Vietzen H, Görzer I, Jaksch P, Puchhammer-Stöckl E.Int J Mol Sci. 2021 Jul 30;22(15):8206. doi: 10.3390/ijms22158206.PMID: 34360986
miRNA-132/212 Gene-Deletion Aggravates the Effect of Oxygen-Glucose Deprivation on Synaptic Functions in the Female Mouse Hippocampus.
Bormann D, Stojanovic T, Cicvaric A, Schuld GJ, Cabatic M, Ankersmit HJ, Monje FJ.Cells. 2021 Jul 6;10(7):1709. doi: 10.3390/cells10071709.PMID: 34359879
Bilateral lung transplantation during pregnancy after ECMO for influenza-A caused ARDS.
Foessleitner P, Hoetzenecker K, Benazzo A, Klebermass-Schrehof K, Scharrer A, Kiss H, Farr A.Am J Transplant. 2021 Oct;21(10):3456-3460. doi: 10.1111/ajt.16781. Epub 2021 Aug 9.PMID: 34331831
Matrix-assisted laser desorption ionization - mass spectrometry imaging of erlotinib reveals a limited tumor tissue distribution in a non-small-cell lung cancer mouse xenograft model.
Kim TY, Lee B, Kim Y, Sugihara Y, Rezeli M, Szasz AM, Dome B, Marko-Varga G, Kwon HJ.Clin Transl Med. 2021 Jul;11(7):e481. doi: 10.1002/ctm2.481.PMID: 34323418
Commentary: To bleed or not to bleed, that is the question-Anticoagulation in surgical patients on prolonged extracorporeal membrane oxygenation.
Schweiger T, Hoetzenecker K.JTCVS Tech. 2020 Aug 12;4:393-394. doi: 10.1016/j.xjtc.2020.07.033. eCollection 2020 Dec.PMID: 34318083
Commentary: When simple living-donor lobar transplantation is just not enough.
Hoetzenecker K.JTCVS Tech. 2020 Aug 12;3:394-395. doi: 10.1016/j.xjtc.2020.07.036. eCollection 2020 Sep.PMID: 34317941
Commentary: Post-COVID-19 acute respiratory distress syndrome and post-COVID-19 fibrosis-the new kids in town.
Schweiger T, Hoetzenecker K.J Thorac Cardiovasc Surg. 2021 Jun 25:S0022-5223(21)00994-6. doi: 10.1016/j.jtcvs.2021.06.040. Online ahead of print.PMID: 34274144
Efficacy and Safety of Percutaneous Pulmonary Artery Subtotal Occlusion and Chronic Total Occlusion Intervention in Chronic Thromboembolic Pulmonary Hypertension.
Gerges C, Friewald R, Gerges M, Shafran I, Sadushi-Koliçi R, Skoro-Sajer N, Moser B, Taghavi S, Klepetko W, Lang IM.Circ Cardiovasc Interv. 2021 Aug;14(8):e010243. doi: 10.1161/CIRCINTERVENTIONS.120.010243. Epub 2021 Jul 16.PMID: 34266313
Lung transplantation for acute respiratory distress syndrome: A multicenter experience.
Frick AE, Gan CT, Vos R, Schwarz S, Kraft F, Kifjak D, Neyrinck AP, Van Raemdonck DE, Klepetko W, Jaksch P, Verschuuren EAM, Hoetzenecker K.Am J Transplant. 2022 Jan;22(1):144-153. doi: 10.1111/ajt.16759. Epub 2021 Jul 24.PMID: 34254423
Multi-omics profiling predicts allograft function after lung transplantation.
Watzenböck ML, Gorki AD, Quattrone F, Gawish R, Schwarz S, Lambers C, Jaksch P, Lakovits K, Zahalka S, Rahimi N, Starkl P, Symmank D, Artner T, Pattaroni C, Fortelny N, Klavins K, Frommlet F, Marsland BJ, Hoetzenecker K, Widder S, Knapp S.Eur Respir J. 2021 Jul 8:2003292. doi: 10.1183/13993003.03292-2020. Online ahead of print.PMID: 34244315
Down-regulation of A20 promotes immune escape of lung adenocarcinomas.
Breitenecker K, Homolya M, Luca AC, Lang V, Trenk C, Petroczi G, Mohrherr J, Horvath J, Moritsch S, Haas L, Kurnaeva M, Eferl R, Stoiber D, Moriggl R, Bilban M, Obenauf AC, Ferran C, Dome B, Laszlo V, Győrffy B, Dezso K, Moldvay J, Casanova E, Moll HP.Sci Transl Med. 2021 Jul 7;13(601):eabc3911. doi: 10.1126/scitranslmed.abc3911.PMID: 34233950
Lung transplantation for COVID-19-associated ARDS - Authors' reply.
Bharat A, Hoetzenecker K, Machuca TN.Lancet Respir Med. 2021 Sep;9(9):e90. doi: 10.1016/S2213-2600(21)00288-5. Epub 2021 Jul 2.PMID: 34224678
Characterization of Tumor-Associated Macrophages and the Immune Microenvironment in Limited-Stage Neuroendocrine-High and -Low Small Cell Lung Cancer.
Dora D, Rivard C, Yu H, Pickard SL, Laszlo V, Harko T, Megyesfalvi Z, Dinya E, Gerdan C, Szegvari G, Hirsch FR, Dome B, Lohinai Z.Biology (Basel). 2021 Jun 4;10(6):502. doi: 10.3390/biology10060502.PMID: 34200100
Association between chronic lung allograft dysfunction and human Cytomegalovirus UL40 peptide variants in lung-transplant recipients.
Vietzen H, Hartenberger S, Jaksch P, Puchhammer-Stöckl E.J Heart Lung Transplant. 2021 Sep;40(9):900-904. doi: 10.1016/j.healun.2021.05.011. Epub 2021 May 31.PMID: 34183227
Cardiopulmonary response to high-altitude mountaineering in lung transplant recipients-The Jebel Toubkal experience.
Schrutka L, Slama A, Muehlbacher J, Bessa V, Lichtenegger P, Ghimessy Á, Ebenbichler G, Winkler R, Faybik P, Nachbaur E, Aigner C, Hoetzenecker K, Jaksch P, Benazzo A.Scand J Med Sci Sports. 2021 Oct;31(10):1941-1948. doi: 10.1111/sms.14008. Epub 2021 Jul 26.PMID: 34170580
Early implementation of renal replacement therapy after lung transplantation does not impair long-term kidney function in patients with idiopathic pulmonary arterial hypertension.
Benazzo A, Bajorek L, Morscher A, Schrutka L, Schaden E, Klepetko W, Hoetzenecker K; Vienna Lung Transplantation Program.J Thorac Cardiovasc Surg. 2021 Jun 1:S0022-5223(21)00879-5. doi: 10.1016/j.jtcvs.2021.05.034. Online ahead of print.PMID: 34144824
[Osteoporosis in pneumological diseases : Joint guideline of the Austrian Society for Bone and Mineral Research (ÖGKM) and the Austrian Society for Pneumology (ÖGP)].
Muschitz C, Zwick RH, Haschka J, Dimai HP, Rauner M, Amrein K, Wakolbinger R, Jaksch P, Eber E, Pietschmann P.Wien Klin Wochenschr. 2021 Jun;133(Suppl 4):155-173. doi: 10.1007/s00508-021-01896-x. Epub 2021 Jun 16.PMID: 34132916
Oblique Carinal End-to-End-Anastomosis for Pig Bronchus in Organ Donor and Lung Transplant Recipient.
Boehm PM, Sinn K, Schwarz S, Kollmann D, Berlakovich G, Hoetzenecker K.Ann Thorac Surg. 2021 Jun 5:S0003-4975(21)00986-3. doi: 10.1016/j.athoracsur.2021.05.029. Online ahead of print.PMID: 34102182
[Predictive relevance of KRAS mutational status in bone metastatic lung adenocarcinoma treated with bisphosphonate therapy].
Radeczky P, Megyesfalvi Z, Fillinger J, László V, Rásó E, Moldvay J, Schlegl E, Barbai T, Bogos K, Tímár J, Rényi-Vámos F, Hegedűs B, Döme B.Magy Onkol. 2021 Jun 3;65(2):103-111. Epub 2021 May 8.PMID: 34081758
Thymomectomy plus total thymectomy versus simple thymomectomy for early-stage thymoma without myasthenia gravis: a European Society of Thoracic Surgeons Thymic Working Group Study.
Guerrera F, Falcoz PE, Moser B, van Raemdonck D, Bille' A, Toker A, Spaggiari L, Ampollini L, Filippini C, Thomas PA, Verdonck B, Mendogni P, Aigner C, Voltolini L, Novoa N, Patella M, Mantovani S, Bravio IG, Zisis C, Guirao A, Londero F, Congregado M, Rocco G, Du Pont B, Martucci N, Esch M, Brunelli A, Detterbeck FC, Venuta F, Weder W, Ruffini E; European Society of Thoracic Surgeons (ESTS) Thymic Working Group Participating Centers, Klepetko W, Olland A, Du Pont B, Nonaka D, Ozkan B, Lo Iacono G, Braggio C, Filosso PL, Brioude G, van Schil P, Nosotti M, Valdivia D, Bongiolatti S, Inci I, Dimitra R, Sànchez D, Grossi W, Moreno-Merino S, Teschner M.Eur J Cardiothorac Surg. 2021 Oct 22;60(4):881-887. doi: 10.1093/ejcts/ezab224.PMID: 34023891
Prognostic impact of PD-1 and PD-L1 expression in malignant pleural mesothelioma: an international multicenter study.
Brcic L, Klikovits T, Megyesfalvi Z, Mosleh B, Sinn K, Hritcu R, Laszlo V, Cufer T, Rozman A, Kern I, Mohorcic K, Jakopovic M, Samarzija M, Seiwerth S, Kolek V, Fischer O, Jakubec P, Škarda J, Gieszer B, Hegedus B, Fillinger J, Renyi-Vamos F, Buder A, Bilecz A, Berger W, Grusch M, Hoetzenecker K, Klepetko W, Hoda MA, Filipits M, Dome B.Transl Lung Cancer Res. 2021 Apr;10(4):1594-1607. doi: 10.21037/tlcr-20-1114.PMID: 34012777
Commentary: The Ethical Dilemma of Multiple Listing.
Hoetzenecker K.Semin Thorac Cardiovasc Surg. 2021 May 15:S1043-0679(21)00239-2. doi: 10.1053/j.semtcvs.2021.04.045. Online ahead of print.PMID: 34004294
Distinct composition and metabolic functions of human gut microbiota are associated with cachexia in lung cancer patients.
Ni Y, Lohinai Z, Heshiki Y, Dome B, Moldvay J, Dulka E, Galffy G, Berta J, Weiss GJ, Sommer MOA, Panagiotou G.ISME J. 2021 Nov;15(11):3207-3220. doi: 10.1038/s41396-021-00998-8. Epub 2021 May 17.PMID: 34002024
Dysbalance of ACE2 levels - a possible cause for severe COVID-19 outcome in COPD.
Fließer E, Birnhuber A, Marsh LM, Gschwandtner E, Klepetko W, Olschewski H, Kwapiszewska G.J Pathol Clin Res. 2021 May 12. doi: 10.1002/cjp2.224. Online ahead of print.PMID: 33978304
Completion Pneumonectomy for Second Primary/Primary Lung Cancer and Local Recurrence Lung Cancer.
Miyahara N, Nii K, Benazzo A, Iwasaki A, Klepetko W, Hoetzenecker K.Ann Thorac Surg. 2021 May 5:S0003-4975(21)00831-6. doi: 10.1016/j.athoracsur.2021.04.063. Online ahead of print.PMID: 33964258
Lung Cancer in Austria.
Pirker R, Prosch H, Popper H, Klepetko W, Dieckmann K, Burghuber OC, Klikovits T, Hoda MA, Zöchbauer-Müller S, Filipits M.J Thorac Oncol. 2021 May;16(5):725-733. doi: 10.1016/j.jtho.2020.10.158.PMID: 33896572
Involvement of CFTR in the pathogenesis of pulmonary arterial hypertension.
Le Ribeuz H, To L, Ghigna MR, Martin C, Nagaraj C, Dreano E, Rucker-Martin C, Girerd B, Bouliguan J, Pechoux C, Lambert M, Boet A, Issard J, Mercier O, Hoetzenecker K, Manoury B, Becq F, Burgel PR, Cottart CH, Olschewski A, Sermet-Gaudelus I, Perros F, Humbert M, Montani D, Antigny F.Eur Respir J. 2021 Apr 29:2000653. doi: 10.1183/13993003.00653-2020. Online ahead of print.PMID: 33926975
Lung Transplantation and Simultaneous Modified Ravitch Procedure.
Matilla JR, Lang G, Rahimi N, Hoetzenecker K.Ann Thorac Surg. 2021 Mar 31:S0003-4975(21)00591-9. doi: 10.1016/j.athoracsur.2021.03.062. Online ahead of print.PMID: 33811886
Early outcomes after lung transplantation for severe COVID-19: a series of the first consecutive cases from four countries.
Bharat A, Machuca TN, Querrey M, Kurihara C, Garza-Castillon R Jr, Kim S, Manerikar A, Pelaez A, Pipkin M, Shahmohammadi A, Rackauskas M, Kg SR, Balakrishnan KR, Jindal A, Schaheen L, Hashimi S, Buddhdev B, Arjuna A, Rosso L, Palleschi A, Lang C, Jaksch P, Budinger GRS, Nosotti M, Hoetzenecker K.Lancet Respir Med. 2021 May;9(5):487-497. doi: 10.1016/S2213-2600(21)00077-1. Epub 2021 Mar 31.PMID: 33811829
Potential novel biomarkers for chronic lung allograft dysfunction and azithromycin responsive allograft dysfunction.
Veraar C, Kliman J, Benazzo A, Oberndorfer F, Laggner M, Hacker P, Raunegger T, Janik S, Jaksch P, Klepetko W, Ankersmit HJ, Moser B.Sci Rep. 2021 Mar 24;11(1):6799. doi: 10.1038/s41598-021-85949-1.PMID: 33762606
Laryngotracheal resection can be performed safely without a guardian Chin stitch-a single-centre experience including 165 consecutive patients.
Schweiger T, Evermann M, Roesner I, Frick AE, Denk-Linnert DM, Klepetko W, Hoetzenecker K.Eur J Cardiothorac Surg. 2021 Mar 10:ezab092. doi: 10.1093/ejcts/ezab092. Online ahead of print.PMID: 33693661
Transient perioperative inflammation following lung transplantation and major thoracic surgery with elective extracorporeal support: a prospective observational study.
Veraar C, Schwarz S, Thanner J, Direder M, Boehm PM, Harnoncourt L, Ortmayr J, Veraar C, Mascherbauer J, Klepetko W, Dworschak M, Ankersmit HJ, Moser B.Ann Transl Med. 2021 Mar;9(5):385. doi: 10.21037/atm-20-4771.PMID: 33842606
Neutrophil extracellular traps promote fibrous vascular occlusions in chronic thrombosis.
Sharma S, Hofbauer TM, Ondracek AS, Chausheva S, Alimohammadi A, Artner T, Panzenboeck A, Rinderer J, Shafran I, Mangold A, Winker R, Wohlschläger-Krenn E, Moser B, Taghavi S, Klepetko W, Preissner KT, Lang IM.Blood. 2021 Feb 25;137(8):1104-1116. doi: 10.1182/blood.2020005861.PMID: 33512471
Comparing the efficacy of γ- and electron-irradiation of PBMCs to promote secretion of paracrine, regenerative factors.
Laggner M, Gugerell A, Copic D, Jeitler M, Springer M, Peterbauer A, Kremslehner C, Filzwieser-Narzt M, Gruber F, Madlener S, Erb M, Widder J, Lechner W, Georg D, Mildner M, Ankersmit HJ.Mol Ther Methods Clin Dev. 2021 Feb 24;21:14-27. doi: 10.1016/j.omtm.2021.02.016. eCollection 2021 Jun 11.PMID: 33768126
Molecular profiles of small cell lung cancer subtypes: therapeutic implications.
Schwendenwein A, Megyesfalvi Z, Barany N, Valko Z, Bugyik E, Lang C, Ferencz B, Paku S, Lantos A, Fillinger J, Rezeli M, Marko-Varga G, Bogos K, Galffy G, Renyi-Vamos F, Hoda MA, Klepetko W, Hoetzenecker K, Laszlo V, Dome B.Mol Ther Oncolytics. 2021 Feb 6;20:470-483. doi: 10.1016/j.omto.2021.02.004. eCollection 2021 Mar 26.PMID: 33718595
Commentary: A journey of a thousand miles begins with a single step.
Frick AE, Hoetzenecker K.J Thorac Cardiovasc Surg. 2021 Feb 6:S0022-5223(21)00215-4. doi: 10.1016/j.jtcvs.2021.01.116. Online ahead of print.PMID: 33648727
The landscape of small cell lung cancer metastases: Organ specificity and timing.
Megyesfalvi Z, Tallosy B, Pipek O, Fillinger J, Lang C, Klikovits T, Schwendenwein A, Hoda MA, Renyi-Vamos F, Laszlo V, Rezeli M, Moldvay J, Dome B.Thorac Cancer. 2021 Mar;12(6):914-923. doi: 10.1111/1759-7714.13854. Epub 2021 Feb 3.PMID: 33533174
Commentary: Say yes to NO!
Benazzo A, Hoetzenecker K.J Thorac Cardiovasc Surg. 2021 Jan 12:S0022-5223(20)33415-2. doi: 10.1016/j.jtcvs.2020.12.061. Online ahead of print.PMID: 33451842
Safety and clinical efficacy of the secretome of stressed peripheral blood mononuclear cells in patients with diabetic foot ulcer-study protocol of the randomized, placebo-controlled, double-blind, multicenter, international phase II clinical trial MARSYAS II.
Gugerell A, Gouya-Lechner G, Hofbauer H, Laggner M, Trautinger F, Almer G, Peterbauer-Scherb A, Seibold M, Hoetzenecker W, Dreschl C, Mildner M, Ankersmit HJ.Trials. 2021 Jan 6;22(1):10. doi: 10.1186/s13063-020-04948-1.PMID: 33407796
Combined low-dose everolimus and low-dose tacrolimus after Alemtuzumab induction therapy: a randomized prospective trial in lung transplantation.
Benazzo A, Cho A, Nechay A, Schwarz S, Frommlet F, Wekerle T, Hoetzenecker K, Jaksch P.Trials. 2021 Jan 4;22(1):6. doi: 10.1186/s13063-020-04843-9.PMID: 33397442
Fractional heat shock protein 27 urine excretion as a short-term predictor in acute exacerbation of chronic obstructive pulmonary disease.
Traxler D, Zimmermann M, Simader E, Einwallner E, Copic D, Graf A, Mueller T, Veraar C, Lainscak M, Marčun R, Košnik M, Fležar M, Rozman A, Korošec P, Klepetko W, Moser B, Ankersmit HJ.Ann Transl Med. 2021 Jan;9(2):117. doi: 10.21037/atm-20-3683.PMID: 33569419
Malignant pleural mesothelioma: recent developments.
Sinn K, Mosleh B, Hoda MA.Curr Opin Oncol. 2021 Jan;33(1):80-86. doi: 10.1097/CCO.0000000000000697.PMID: 33186182
Functional outcome after single-stage laryngotracheal reconstruction with rib cartilage grafting.
Schweiger T, Roesner I, de Faria Soares Rodrigues I, Evermann M, Frick AE, Denk-Linnert DM, Klepetko W, Hoetzenecker K.J Thorac Cardiovasc Surg. 2020 Dec 11:S0022-5223(20)33315-8. doi: 10.1016/j.jtcvs.2020.11.155. Online ahead of print.PMID: 33640122
Current therapy of KRAS-mutant lung cancer.
Ghimessy A, Radeczky P, Laszlo V, Hegedus B, Renyi-Vamos F, Fillinger J, Klepetko W, Lang C, Dome B, Megyesfalvi Z.Cancer Metastasis Rev. 2020 Dec;39(4):1159-1177. doi: 10.1007/s10555-020-09903-9.PMID: 32548736
Is chronological age still a hard selection criterion for lung transplantation?
Schweiger T, Hoetzenecker K.J Heart Lung Transplant. 2021 Feb;40(2):99-100. doi: 10.1016/j.healun.2020.11.011. Epub 2020 Nov 28.PMID: 33309327
Lungs from polytrauma donors with significant chest trauma can be safely used for transplantation.
Schwarz S, Rahimi N, Kifjak D, Frommlet F, Benazzo A, Jaksch P, Klepetko W, Hoetzenecker K; Vienna Lung Transplant Group.J Thorac Cardiovasc Surg. 2020 Nov 27:S0022-5223(20)33139-1. doi: 10.1016/j.jtcvs.2020.10.150. Online ahead of print.PMID: 33451825
Comparison of donor scores in bilateral lung transplantation-A large single-center analysis.
Schwarz S, Rahimi N, Kifjak D, Muckenhuber M, Watzenböck M, Benazzo A, Jaksch P, Knapp S, Klepetko W, Hoetzenecker K; Vienna Lung Transplant Group.Am J Transplant. 2020 Nov 19. doi: 10.1111/ajt.16402. Online ahead of print.PMID: 33210825
Commentary: Selection criteria for lung transplantation-is there room for individualization?
Jaksch P, Hoetzenecker K.J Thorac Cardiovasc Surg. 2020 Nov 9:S0022-5223(20)33016-6. doi: 10.1016/j.jtcvs.2020.10.119. Online ahead of print.PMID: 33288236
TGF-β in the Secretome of Irradiated Peripheral Blood Mononuclear Cells Supports In Vitro Osteoclastogenesis.
Panahipour L, Kargarpour Z, Laggner M, Mildner M, Ankersmit HJ, Gruber R.Int J Mol Sci. 2020 Nov 13;21(22):E8569. doi: 10.3390/ijms21228569.PMID: 33202935
Malignant pleural mesothelioma: recent developments.
Sinn K, Mosleh B, Hoda MA.Curr Opin Oncol. 2020 Nov 11. doi: 10.1097/CCO.0000000000000697. Online ahead of print.PMID: 33186182
TWIST1 Drives Smooth Muscle Cell Proliferation in Pulmonary Hypertension via Loss of GATA-6 and BMPR2.
Fan Y, Gu X, Zhang J, Sinn K, Klepetko W, Wu N, Foris V, Solymosi P, Kwapiszewska G, Kuebler WM.Am J Respir Crit Care Med. 2020 Nov 1;202(9):1283-1296. doi: 10.1164/rccm.201909-1884OC.PMID: 32692930
Infraglottic versus supraglottic jet-ventilation for endobronchial ultrasound-guided transbronchial needle aspiration: A randomised controlled trial.
Anwar M, Fritze R, Base E, Wasserscheid T, Wolfram N, Koinig H, Hackner K, Lambers C, Schweiger T, Errhalt P, Hoda MA.Eur J Anaesthesiol. 2020 Nov;37(11):999-1007. doi: 10.1097/EJA.0000000000001220.PMID: 32453167
Targeted Therapy Recommendations for Therapy Refractory Solid Tumors-Data from the Real-World Precision Medicine Platform MONDTI.
Taghizadeh H, Unseld M, Spalt M, Mader RM, Müllauer L, Fuereder T, Raderer M, Sibilia M, Hoda MA, Aust S, Polterauer S, Lamm W, Bartsch R, Preusser M, A KW, Prager GW.J Pers Med. 2020 Oct 23;10(4):E188. doi: 10.3390/jpm10040188.PMID: 33114048
3D histopathology of human tumours by fast clearing and ultramicroscopy.
Sabdyusheva Litschauer I, Becker K, Saghafi S, Ballke S, Bollwein C, Foroughipour M, Gaugeler J, Foroughipour M, Schavelová V, László V, Döme B, Brostjan C, Weichert W, Dodt HU.Sci Rep. 2020 Oct 19;10(1):17619. doi: 10.1038/s41598-020-71737-w.PMID: 33077794
Ventilation parameters and early graft function in double lung transplantation.
Schwarz S, Benazzo A, Dunkler D, Muckenhuber M, Sorbo LD, Nardo MD, Sinn K, Moser B, Matilla JR, Lang G, Taghavi S, Vamos FR, Jaksch P, Cypel M, Keshavjee S, Klepetko W, Hoetzenecker K.J Heart Lung Transplant. 2020 Oct 13:S1053-2498(20)31786-1. doi: 10.1016/j.healun.2020.10.003. Online ahead of print.PMID: 33144029
Prostaglandin D2 strengthens human endothelial barrier by activation of E-type receptor 4.
Rittchen S, Rohrer K, Platzer W, Knuplez E, Bärnthaler T, Marsh LM, Atallah R, Sinn K, Klepetko W, Sharma N, Nagaraj C, Heinemann A.Biochem Pharmacol. 2020 Oct 8;182:114277. doi: 10.1016/j.bcp.2020.114277. Online ahead of print.PMID: 33038299
Longitudinal analysis of complete blood count parameters in advanced-stage lung cancer patients.
Rojko L, Megyesfalvi Z, Czibula E, Reiniger L, Teglasi V, Szegedi Z, Szallasi Z, Dome B, Moldvay J.Thorac Cancer. 2020 Nov;11(11):3193-3204. doi: 10.1111/1759-7714.13642. Epub 2020 Sep 17.PMID: 32941706
DNA Polymerase Alpha Subunit B Is a Binding Protein for Erlotinib Resistance in Non-Small Cell Lung Cancer.
Kim TY, Ji ES, Lee JY, Kim JY, Yoo JS, Szasz AM, Dome B, Marko-Varga G, Kwon HJ.Cancers (Basel). 2020 Sep 13;12(9):2613. doi: 10.3390/cancers12092613.PMID: 32933200
Platinum Drug Sensitivity Polymorphisms in Stage III Non-small Cell Lung Cancer With Invasion of Mediastinal Lymph Nodes.
Nastase A, Lupo A, Laszlo V, Damotte D, Dima S, Canny E, Alifano M, Popescu I, Klepetko W, Grigoroiu M.Cancer Genomics Proteomics. 2020 Sep-Oct;17(5):587-595. doi: 10.21873/cgp.20215.PMID: 32859637
Endothelial Dysfunction Following Enhanced TMEM16A Activity in Human Pulmonary Arteries.
Skofic Maurer D, Zabini D, Nagaraj C, Sharma N, Lengyel M, Nagy BM, Frank S, Klepetko W, Gschwandtner E, Enyedi P, Kwapiszewska G, Olschewski H, Olschewski A.Cells. 2020 Aug 28;9(9):1984. doi: 10.3390/cells9091984.PMID: 32872351
Molecular T-cell‒mediated rejection in transbronchial and mucosal lung transplant biopsies is associated with future risk of graft loss.
Halloran K, Parkes MD, Timofte I, Snell G, Westall G, Havlin J, Lischke R, Hachem R, Kreisel D, Levine D, Kubisa B, Piotrowska M, Juvet S, Keshavjee S, Jaksch P, Klepetko W, Hirji A, Weinkauf J, Halloran PF.J Heart Lung Transplant. 2020 Aug 26:S1053-2498(20)31702-2. doi: 10.1016/j.healun.2020.08.013. Online ahead of print.PMID: 32943286
Lung transplantation for COVID-19-associated acute respiratory distress syndrome in a PCR-positive patient.
Lang C, Jaksch P, Hoda MA, Lang G, Staudinger T, Tschernko E, Zapletal B, Geleff S, Prosch H, Gawish R, Knapp S, Robak O, Thalhammer F, Indra A, Koestenberger M, Strassl R, Klikovits T, Ali K, Fischer G, Klepetko W, Hoetzenecker K, Schellongowski P.Lancet Respir Med. 2020 Oct;8(10):1057-1060. doi: 10.1016/S2213-2600(20)30361-1. Epub 2020 Aug 25.PMID: 32857987
Activin A: an emerging target for improving cancer treatment?
Ries A, Schelch K, Falch D, Pany L, Hoda MA, Grusch M.Expert Opin Ther Targets. 2020 Oct;24(10):985-996. doi: 10.1080/14728222.2020.1799350. Epub 2020 Aug 6.PMID: 32700590
The inflammatory markers sST2, HSP27 and hsCRP as a prognostic biomarker panel in chronic heart failure patients.
Traxler D, Zimmermann M, Simader E, Veraar CM, Moser B, Mueller T, Mildner M, Dannenberg V, Lainscak M, Jug B, Ankersmit HJ.Clin Chim Acta. 2020 Nov;510:507-514. doi: 10.1016/j.cca.2020.07.050. Epub 2020 Jul 29.PMID: 32735982
Neuroendocrine subtypes of small cell lung cancer differ in terms of immune microenvironment and checkpoint molecule distribution.
Dora D, Rivard C, Yu H, Bunn P, Suda K, Ren S, Lueke Pickard S, Laszlo V, Harko T, Megyesfalvi Z, Moldvay J, Hirsch FR, Dome B, Lohinai Z.Mol Oncol. 2020 Sep;14(9):1947-1965. doi: 10.1002/1878-0261.12741. Epub 2020 Jul 18.PMID: 32506804
Neurological symptom burden impacts survival prognosis in patients with newly diagnosed non-small cell lung cancer brain metastases.
Steindl A, Yadavalli S, Gruber KA, Seiwald M, Gatterbauer B, Dieckmann K, Frischer JM, Klikovits T, Zöchbauer-Müller S, Grisold A, Hoda MAR, Marosi C, Widhalm G, Preusser M, Berghoff AS.Cancer. 2020 Jul 17;126(19):4341-52. doi: 10.1002/cncr.33085. Online ahead of print.PMID: 32678971
Recommendations for extracorporeal membrane oxygenation (ECMO) in COVID-19 patients : Consensus paper of the Medical University of Vienna.
Wiedemann D, Bernardi MH, Distelmaier K, Goliasch G, Hengstenberg C, Hermann A, Holzer M, Hoetzenecker K, Klepetko W, Lang G, Lassnigg A, Laufer G, Magnet IAM, Markstaller K, Röggla M, Rössler B, Schellongowski P, Simon P, Tschernko E, Ullrich R, Zimpfer D, Staudinger T; COVID-19 ECMO Research Group Medical University of Vienna.Wien Klin Wochenschr. 2020 Jul 3:1-6. doi: 10.1007/s00508-020-01708-8. Online ahead of print.PMID: 32621065
Simultaneous pectus excavatum correction and lung transplantation-A case series.
Rahimi N, Matilla JR, Lang G, Schwarz S, Nachbaur E, Benazzo A, Klepetko W, Jaksch P, Hoetzenecker K.Am J Transplant. 2020 Jul 3. doi: 10.1111/ajt.16180. Online ahead of print.PMID: 3261907
Publisher Correction: A clonal expression biomarker associates with lung cancer mortality.
Biswas D, Birkbak NJ, Rosenthal R, Hiley CT, Lim EL, Papp K, Boeing S, Krzystanek M, Djureinovic D, La Fleur L, Greco M, Döme B, Fillinger J, Brunnström H, Wu Y, Moore DA, Skrzypski M, Abbosh C, Litchfield K, Al Bakir M, Watkins TBK, Veeriah S, Wilson GA, Jamal-Hanjani M, Moldvay J, Botling J, Chinnaiyan AM, Micke P, Hackshaw A, Bartek J, Csabai I, Szallasi Z, Herrero J, McGranahan N, Swanton C; TRACERx Consortium.Nat Med. 2020 Jul;26(7):1148. doi: 10.1038/s41591-020-0899-z.PMID: 32494065
ERS/ESTS/EACTS/ESTRO guidelines for the management of malignant pleural mesothelioma.
Opitz I, Scherpereel A, Berghmans T, Psallidas I, Glatzer M, Rigau D, Astoul P, Bölükbas S, Boyd J, Coolen J, De Bondt C, De Ruysscher D, Durieux V, Faivre-Finn C, Fennell DA, Galateau-Salle F, Greillier L, Hoda MA, Klepetko W, Lacourt A, McElnay P, Maskell NA, Mutti L, Pairon JC, Van Schil P, van Meerbeeck JP, Waller D, Weder W, Putora PM, Cardillo G.Eur J Cardiothorac Surg. 2020 Jul 1;58(1):1-24. doi: 10.1093/ejcts/ezaa158.PMID: 32448904
Basement Membrane Remodeling Controls Endothelial Function in Idiopathic Pulmonary Arterial Hypertension.
Jandl K, Marsh LM, Hoffmann J, Mutgan AC, Baum O, Bloch W, Thekkekara-Puthenparampil H, Kolb D, Sinn K, Klepetko W, Heinemann A, Olschewski A, Olschewski H, Kwapiszewska G.Am J Respir Cell Mol Biol. 2020 Jul;63(1):104-117. doi: 10.1165/rcmb.2019-0303OC.PMID: 32160015
Role for Lipids Secreted by Irradiated Peripheral Blood Mononuclear Cells in Inflammatory Resolution in Vitro.
Panahipour L, Kochergina E, Laggner M, Zimmermann M, Mildner M, Ankersmit HJ, Gruber R.Int J Mol Sci. 2020 Jun 30;21(13):4694. doi: 10.3390/ijms21134694.PMID: 32630157
HDAC Inhibition Induces PD-L1 Expression in a Novel Anaplastic Thyroid Cancer Cell Line.
Hegedűs L, Rittler D, Garay T, Stockhammer P, Kovács I, Döme B, Theurer S, Hager T, Herold T, Kalbourtzis S, Bankfalvi A, Schmid KW, Führer D, Aigner C, Hegedűs B.Pathol Oncol Res. 2020 Oct;26(4):2523-2535. doi: 10.1007/s12253-020-00834-y. Epub 2020 Jun 26.PMID: 32591993
Impact of donor time to cardiac arrest in lung donation after circulatory death.
Qaqish R, Watanabe Y, Hoetzenecker K, Yeung J, Chen M, Pierre A, Yasufuku K, Donahoe L, de Perrot M, Waddell T, Keshavjee S, Cypel M.J Thorac Cardiovasc Surg. 2020 Jun 16:S0022-5223(20)31407-0. doi: 10.1016/j.jtcvs.2020.04.181. Online ahead of print.PMID: 32747131
Current therapy of KRAS-mutant lung cancer.
Ghimessy A, Radeczky P, Laszlo V, Hegedus B, Renyi-Vamos F, Fillinger J, Klepetko W, Lang C, Dome B, Megyesfalvi Z.Cancer Metastasis Rev. 2020 Jun 16. doi: 10.1007/s10555-020-09903-9. Online ahead of print.PMID: 32548736
Quantitative Hybrid Cardiac [18F]FDG-PET-MRI Images for Assessment of Cardiac Repair by Preconditioned Cardiosphere-Derived Cells.
Winkler J, Lukovic D, Mester-Tonczar J, Zlabinger K, Gugerell A, Pavo N, Jakab A, Szankai Z, Traxler D, Müller C, Spannbauer A, Riesenhuber M, Hašimbegović E, Dawkins J, Zimmermann M, Ankersmit HJ, Marbán E, Gyöngyösi M.Mol Ther Methods Clin Dev. 2020 Jun 15;18:354-366. doi: 10.1016/j.omtm.2020.06.008. eCollection 2020 Sep 11.PMID: 32671138
Long-term survival after salvage surgery for a giant primary rib osteosarcoma.
Sinn K, Hritcu R, Mosleh B, Köstler W, Taghavi S, Klepetko W, Hoda MA, Klikovits T.Ann Thorac Surg. 2020 Jun 15:S0003-4975(20)30929-2. doi: 10.1016/j.athoracsur.2020.04.116. Online ahead of print.PMID: 32553768
Proteomic analysis enables distinction of early- versus advanced-stage lung adenocarcinomas.
Kelemen O, Pla I, Sanchez A, Rezeli M, Szasz AM, Malm J, Laszlo V, Kwon HJ, Dome B, Marko-Varga G.Clin Transl Med. 2020 Jun 14;10(2):e106. doi: 10.1002/ctm2.106. Online ahead of print.PMID: 32536039
NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD.
Seimetz M, Sommer N, Bednorz M, Pak O, Veith C, Hadzic S, Gredic M, Parajuli N, Kojonazarov B, Kraut S, Wilhelm J, Knoepp F, Henneke I, Pichl A, Kanbagli ZI, Scheibe S, Fysikopoulos A, Wu CY, Klepetko W, Jaksch P, Eichstaedt C, Grünig E, Hinderhofer K, Geiszt M, Müller N, Rezende F, Buchmann G, Wittig I, Hecker M, Hecker A, Padberg W, Dorfmüller P, Gattenlöhner S, Vogelmeier CF, Günther A, Karnati S, Baumgart-Vogt E, Schermuly RT, Ghofrani HA, Seeger W, Schröder K, Grimminger F, Brandes RP, Weissmann N.Nat Metab. 2020 Jun;2(6):532-546. doi: 10.1038/s42255-020-0215-8. Epub 2020 Jun 8.PMID: 32694733
Comparative analysis of prognostic histopathologic parameters in subtypes of epithelioid pleural mesothelioma.
Bilecz A, Stockhammer P, Theegarten D, Kern I, Jakopovic M, Samarzija M, Klikovits T, Hoda MA, Döme B, Oberndorfer F, Muellauer L, Fillinger J, Kovács I, Pirker C, Schuler M, Plönes T, Aigner C, Klepetko W, Berger W, Brcic L, Laszlo V, Hegedus B.Histopathology. 2020 Jul;77(1):55-66. doi: 10.1111/his.14105. Epub 2020 May 25.PMID: 32170970
Gender differences in molecular-guided therapy recommendations for metastatic malignant mesothelioma.
Taghizadeh H, Zöchbauer-Müller S, Mader RM, Müllauer L, Klikovits T, Bachleitner-Hofmann T, Hoda MA, Prager GW.Thorac Cancer. 2020 Jul;11(7):1979-1988. doi: 10.1111/1759-7714.13491. Epub 2020 May 21.PMID: 32438515
Heat shock protein 90α in thymic epithelial tumors and non-thymomatous myasthenia gravis.
Thanner J, Bekos C, Veraar C, Janik S, Laggner M, Boehm PM, Schiefer AI, Müllauer L, Klepetko W, Ankersmit HJ, Moser B.Oncoimmunology. 2020 May 13;9(1):1756130. doi: 10.1080/2162402X.2020.1756130.PMID: 32923112
Outcome of Extracorporeal Photopheresis as an Add-On Therapy for Antibody-Mediated Rejection in Lung Transplant Recipients.
Benazzo A, Worel N, Schwarz S, Just U, Nechay A, Lambers C, Böhmig G, Fischer G, Koren D, Muraközy G, Knobler R, Klepetko W, Hoetzenecker K, Jaksch P.Transfus Med Hemother. 2020 Jun;47(3):205-213. doi: 10.1159/000508170. Epub 2020 May 5.PMID: 32595425
Commentary: Lobar lung transplantation: Trick or treat-(ment).
Lang G, Klepetko W.J Thorac Cardiovasc Surg. 2020 May 1:S0022-5223(20)31043-6. doi: 10.1016/j.jtcvs.2020.04.084. Online ahead of print.PMID: 32532506
Therapeutic potential of lipids obtained from γ-irradiated PBMCs in dendritic cell-mediated skin inflammation.
Laggner M, Copic D, Nemec L, Vorstandlechner V, Gugerell A, Gruber F, Peterbauer A, Ankersmit HJ, Mildner M.EBioMedicine. 2020 May;55:102774. doi: 10.1016/j.ebiom.2020.102774. Epub 2020 May 8.PMID: 32403085
Telomerase Reverse Transcriptase Promoter Mutations Identify a Genomically Defined and Highly Aggressive Human Pleural Mesothelioma Subgroup.
Pirker C, Bilecz A, Grusch M, Mohr T, Heidenreich B, Laszlo V, Stockhammer P, Lötsch-Gojo D, Gojo J, Gabler L, Spiegl-Kreinecker S, Dome B, Steindl A, Klikovits T, Hoda MA, Jakopovic M, Samarzija M, Mohorcic K, Kern I, Kiesel B, Brcic L, Oberndorfer F, Müllauer L, Klepetko W, Schmidt WM, Kumar R, Hegedus B, Berger W.Clin Cancer Res. 2020 Jul 15;26(14):3819-3830. doi: 10.1158/1078-0432.CCR-19-3573. Epub 2020 Apr 21.PMID: 32317288
Laryngeal Mask as the Primary Airway Device During Laryngotracheal Surgery: Data From 108 Patients.
Schweiger T, de Faria Soares Rodrigues I, Roesner I, Schneider-Stickler B, Evermann M, Denk-Linnert DM, Hager H, Klepetko W, Hoetzenecker K.Ann Thorac Surg. 2020 Jul;110(1):251-257. doi: 10.1016/j.athoracsur.2019.11.064. Epub 2020 Mar 19.PMID: 32199826
Plasma Levels of the Bioactive Sphingolipid Metabolite S1P in Adult Cystic Fibrosis Patients: Potential Target for Immunonutrition?
Halilbasic E, Fuerst E, Heiden D, Japtok L, Diesner SC, Trauner M, Kulu A, Jaksch P, Hoetzenecker K, Kleuser B, Kazemi-Shirazi L, Untersmayr E.Nutrients. 2020 Mar 14;12(3):765. doi: 10.3390/nu12030765.PMID: 32183316
Single running suture technique is associated with low rate of bronchial complications after lung transplantation.
Schweiger T, Nenekidis I, Stadler JE, Schwarz S, Benazzo A, Jaksch P, Hoetzenecker K, Klepetko W; Vienna Lung Transplant Program.J Thorac Cardiovasc Surg. 2020 Oct;160(4):1099-1108.e3. doi: 10.1016/j.jtcvs.2019.12.119. Epub 2020 Feb 19.PMID: 32580901
Low molecular weight heparin versus unfractioned heparin for anticoagulation during perioperative extracorporeal membrane oxygenation: A single center experience in 102 lung transplant patients.
Gratz J, Pausch A, Schaden E, Baierl A, Jaksch P, Erhart F, Hoetzenecker K, Wiegele M.Artif Organs. 2020 Jun;44(6):638-646. doi: 10.1111/aor.13642. Epub 2020 Feb 18.PMID: 31951030
Chest CT in patients after lung transplantation: A retrospective analysis to evaluate impact on image quality and radiation dose using spectral filtration tin-filtered imaging.
Wressnegger A, Prosch H, Moser B, Klepetko W, Jaksch P, Lambers C, Hoetzenecker K, Schestak C, De Bettignies A, Beer L, Apfaltrer G, Ringl H, Apfaltrer P.PLoS One. 2020 Feb 5;15(2):e0228376. doi: 10.1371/journal.pone.0228376. eCollection 2020.PMID: 32023294
Profiling the Protein Targets of Unmodified Bio-Active Molecules with Drug Affinity Responsive Target Stability and Liquid Chromatography/Tandem Mass Spectrometry.
Hwang HY, Kim TY, Szász MA, Dome B, Malm J, Marko-Varga G, Kwon HJ.Proteomics. 2020 May;20(9):e1900325. doi: 10.1002/pmic.201900325. Epub 2020 Feb 5.PMID: 31926115
Deciphering the functional heterogeneity of skin fibroblasts using single-cell RNA sequencing.
Vorstandlechner V, Laggner M, Kalinina P, Haslik W, Radtke C, Shaw L, Lichtenberger BM, Tschachler E, Ankersmit HJ, Mildner M.FASEB J. 2020 Mar;34(3):3677-3692. doi: 10.1096/fj.201902001RR. Epub 2020 Jan 12.PMID: 31930613
Reproducibility of GMP-compliant production of therapeutic stressed peripheral blood mononuclear cell-derived secretomes, a novel class of biological medicinal products.
Laggner M, Gugerell A, Bachmann C, Hofbauer H, Vorstandlechner V, Seibold M, Gouya Lechner G, Peterbauer A, Madlener S, Demyanets S, Sorgenfrey D, Ostler T, Erb M, Mildner M, Ankersmit HJ.Stem Cell Res Ther. 2020 Jan 3;11(1):9. doi: 10.1186/s13287-019-1524-2.PMID: 31900195
Microvascular Disease in Chronic Thromboembolic Pulmonary Hypertension: Hemodynamic Phenotyping and Histomorphometric Assessment.
Gerges C, Gerges M, Friewald R, Fesler P, Dorfmüller P, Sharma S, Karlocai K, Skoro-Sajer N, Jakowitsch J, Moser B, Taghavi S, Klepetko W, Lang IM.Circulation. 2020 Feb 4;141(5):376-386. doi: 10.1161/CIRCULATIONAHA.119.041515. Epub 2020 Jan 3.PMID: 31896275
Non-pulsatile blood flow is associated with enhanced cerebrovascular carbon dioxide reactivity and an attenuated relationship between cerebral blood flow and regional brain oxygenation.
Veraar CM, Rinösl H, Kühn K, Skhirtladze-Dworschak K, Felli A, Mouhieddine M, Menger J, Pataraia E, Ankersmit HJ, Dworschak M.Crit Care. 2019 Dec 30;23(1):426. doi: 10.1186/s13054-019-2671-7.PMID: 31888721
High degree of polyclonality hinders somatic mutation calling in lung brush samples of COPD cases and controls.
Thun GA, Derdak S, Castro-Giner F, Apunte-Ramos K, Águeda L, Wjst M, Boland A, Deleuze JF, Kolsum U, Heiss-Neumann MS, Nowinski A, Gorecka D, Hohlfeld JM, Welte T, Brightling CE, Parr DG, Prasse A, Müller-Quernheim J, Greulich T, Stendardo M, Boschetto P, Barta I, Döme B, Gut M, Singh D, Ziegler-Heitbrock L, Gut IG.Sci Rep. 2019 Dec 27;9(1):20158. doi: 10.1038/s41598-019-56618-1.PMID: 31882973
Heat shock protein 27 as a predictor of prognosis in patients admitted to hospital with acute COPD exacerbation.
Zimmermann M, Traxler D, Bekos C, Simader E, Mueller T, Graf A, Lainscak M, Marčun R, Košnik M, Fležar M, Rozman A, Korošec P, Klepetko W, Moser B, Ankersmit HJ.Cell Stress Chaperones. 2020 Jan;25(1):141-149. doi: 10.1007/s12192-019-01057-0. Epub 2019 Dec 9.PMID: 31820266
Clinical prognostic scores for patients with thymic epithelial tumors.
Veraar C, Janik S, Thanner J, Veraar C, Mouhieddine M, Schiefer AI, Müllauer L, Dworschak M, Klepetko W, Ankersmit HJ, Moser B.Sci Rep. 2019 Dec 9;9(1):18581. doi: 10.1038/s41598-019-54906-4.PMID: 31819103
Inhibiting eicosanoid degradation exerts antifibrotic effects in a pulmonary fibrosis mouse model and human tissue.
Bärnthaler T, Theiler A, Zabini D, Trautmann S, Stacher-Priehse E, Lanz I, Klepetko W, Sinn K, Flick H, Scheidl S, Thomas D, Olschewski H, Kwapiszewska G, Schuligoi R, Heinemann A.J Allergy Clin Immunol. 2020 Mar;145(3):818-833.e11. doi: 10.1016/j.jaci.2019.11.032. Epub 2019 Dec 5.PMID: 3181257
Comparative expression analysis in small cell lung carcinoma reveals neuroendocrine pattern change in primary tumor versus lymph node metastases.
Lohinai Z, Megyesfalvi Z, Suda K, Harko T, Ren S, Moldvay J, Laszlo V, Rivard C, Dome B, Hirsch FR.Transl Lung Cancer Res. 2019 Dec;8(6):938-950. doi: 10.21037/tlcr.2019.11.30.PMID: 32010572
Molecular phenotyping of rejection-related changes in mucosal biopsies from lung transplants.
Halloran K, Parkes MD, Timofte IL, Snell GI, Westall GP, Hachem R, Kreisel D, Levine D, Juvet S, Keshavjee S, Jaksch P, Klepetko W, Hirji A, Weinkauf J, Halloran PF.Am J Transplant. 2020 Apr;20(4):954-966. doi: 10.1111/ajt.15685. Epub 2019 Dec 1.PMID: 31679176
Bilateral lung transplantation on intraoperative extracorporeal membrane oxygenator: An observational study.
Hoetzenecker K, Benazzo A, Stork T, Sinn K, Schwarz S, Schweiger T, Klepetko W; Vienna Lung Transplant Group.J Thorac Cardiovasc Surg. 2020 Jul;160(1):320-327.e1. doi: 10.1016/j.jtcvs.2019.10.155. Epub 2019 Nov 27.PMID: 31932054
Follistatin impacts Tumor Angiogenesis and Outcome in Thymic Epithelial Tumors.
Janik S, Bekos C, Hacker P, Raunegger T, Schiefer AI, Müllauer L, Veraar C, Dome B, Klepetko W, Ankersmit HJ, Moser B.Sci Rep. 2019 Nov 22;9(1):17359. doi: 10.1038/s41598-019-53671-8.PMID: 31757999
Lung transplantation for pulmonary hypertension with giant pulmonary artery aneurysm.
Schwarz S, Benazzo A, Prosch H, Jaksch P, Klepetko W, Hoetzenecker K; Vienna Lung Transplant Group.J Thorac Cardiovasc Surg. 2020 Jun;159(6):2543-2550. doi: 10.1016/j.jtcvs.2019.09.178. Epub 2019 Oct 26.PMID: 31780060
KRAS Mutations Predict Response and Outcome in Advanced Lung Adenocarcinoma Patients Receiving First-Line Bevacizumab and Platinum-Based Chemotherapy.
Ghimessy AK, Gellert A, Schlegl E, Hegedus B, Raso E, Barbai T, Timar J, Ostoros G, Megyesfalvi Z, Gieszer B, Moldvay J, Renyi-Vamos F, Lohinai Z, Hoda MA, Klikovits T, Klepetko W, Laszlo V, Dome B.Cancers (Basel). 2019 Oct 9;11(10):1514. doi: 10.3390/cancers11101514.PMID: 31600989
Commentary: The cell without qualities?
Kollmann D, Hoetzenecker K.J Thorac Cardiovasc Surg. 2019 Oct 3:S0022-5223(19)32122-1. doi: 10.1016/j.jtcvs.2019.09.107. Online ahead of print.PMID: 31677885
A clonal expression biomarker associates with lung cancer mortality.
Biswas D, Birkbak NJ, Rosenthal R, Hiley CT, Lim EL, Papp K, Boeing S, Krzystanek M, Djureinovic D, La Fleur L, Greco M, Döme B, Fillinger J, Brunnström H, Wu Y, Moore DA, Skrzypski M, Abbosh C, Litchfield K, Al Bakir M, Watkins TBK, Veeriah S, Wilson GA, Jamal-Hanjani M, Moldvay J, Botling J, Chinnaiyan AM, Micke P, Hackshaw A, Bartek J, Csabai I, Szallasi Z, Herrero J, McGranahan N, Swanton C; TRACERx Consortium.Nat Med. 2019 Oct;25(10):1540-1548. doi: 10.1038/s41591-019-0595-z. Epub 2019 Oct 7.PMID: 31591602
Expression of FGFR1-4 in Malignant Pleural Mesothelioma Tissue and Corresponding Cell Lines and its Relationship to Patient Survival and FGFR Inhibitor Sensitivity.
Vlacic G, Hoda MA, Klikovits T, Sinn K, Gschwandtner E, Mohorcic K, Schelch K, Pirker C, Peter-Vörösmarty B, Brankovic J, Dome B, Laszlo V, Cufer T, Rozman A, Klepetko W, Grasl-Kraupp B, Hegedus B, Berger W, Kern I, Grusch M.Cells. 2019 Sep 16;8(9):1091. doi: 10.3390/cells8091091.PMID: 31527449
JAK-STAT inhibition impairs K-RAS-driven lung adenocarcinoma progression.
Mohrherr J, Haber M, Breitenecker K, Aigner P, Moritsch S, Voronin V, Eferl R, Moriggl R, Stoiber D, Győrffy B, Brcic L, László V, Döme B, Moldvay J, Dezső K, Bilban M, Popper H, Moll HP, Casanova E.Int J Cancer. 2019 Dec 15;145(12):3376-3388. doi: 10.1002/ijc.32624. Epub 2019 Sep 10.PMID: 31407334
Normothermic ex vivo lung perfusion: Does the indication impact organ utilization and patient outcomes after transplantation?
Cypel M, Yeung JC, Donahoe L, Chen M, Zamel R, Hoetzenecker K, Yasufuku K, de Perrot M, Pierre AF, Waddell TK, Keshavjee S.J Thorac Cardiovasc Surg. 2019 Sep 9:S0022-5223(19)31732-5. doi: 10.1016/j.jtcvs.2019.06.123. Online ahead of print.PMID: 31606173
Commentary: Leveling up the evidence!
Hoetzenecker K.J Thorac Cardiovasc Surg. 2020 Feb;159(2):731. doi: 10.1016/j.jtcvs.2019.08.011. Epub 2019 Sep 5.PMID: 31619327
IL-1 receptor blockade skews inflammation towards Th2 in a mouse model of systemic sclerosis.
Birnhuber A, Crnkovic S, Biasin V, Marsh LM, Odler B, Sahu-Osen A, Stacher-Priehse E, Brcic L, Schneider F, Cikes N, Ghanim B, Klepetko W, Graninger W, Allanore Y, Eferl R, Olschewski A, Olschewski H, Kwapiszewska G.Eur Respir J. 2019 Sep 29;54(3):1900154. doi: 10.1183/13993003.00154-2019. Print 2019 Sep.PMID: 31320452
Next-Generation Sequencing May Discriminate Extreme Long-term versus Short-term Survival in Patients with Metastatic Small Cell Lung Cancer (SCLC).
Lohinai Z, Megyesfalvi Z, Dome B, Weiss GJ.Transl Oncol. 2019 Dec;12(12):1539-1548. doi: 10.1016/j.tranon.2019.08.004. Epub 2019 Aug 31.PMID: 31476386
Risk factors for early bleeding complications after lung transplantation - a retrospective cohort study.
Adelmann D, Koch S, Menger J, Opfermann P, Jaksch P, Hoetzenecker K, Kurz M, Mouhieddine M, Steinlechner B.Transpl Int. 2019 Dec;32(12):1313-1321. doi: 10.1111/tri.13491. Epub 2019 Aug 30.PMID: 31402529
Prognostic assessment in patients with newly diagnosed small cell lung cancer brain metastases: results from a real-life cohort.
Steindl A, Schlieter F, Klikovits T, Leber E, Gatterbauer B, Frischer JM, Dieckmann K, Widhalm G, Zöchbauer-Müller S, Hoda MAR, Preusser M, Berghoff AS.J Neurooncol. 2019 Oct;145(1):85-95. doi: 10.1007/s11060-019-03269-x. Epub 2019 Aug 27.PMID: 31456143
Publisher Correction: Exercise-induced bronchoconstriction, temperature regulation and the role of heat shock proteins in non-asthmatic recreational marathon and half-marathon runners.
Bekos C, Zimmermann M, Unger L, Janik S, Mitterbauer A, Koller M, Fritz R, Gäbler C, Didcock J, Kliman J, Klepetko W, Ankersmit HJ, Moser B.Sci Rep. 2019 Aug 22;9(1):12381. doi: 10.1038/s41598-019-48897-5.PMID: 31434997
Neutrophil-lymphocyte ratio is prognostic in early stage resected small-cell lung cancer.
Lohinai Z, Bonanno L, Aksarin A, Pavan A, Megyesfalvi Z, Santa B, Hollosi V, Hegedus B, Moldvay J, Conte P, Ter-Ovanesov M, Bilan E, Dome B, Weiss GJ.PeerJ. 2019 Jul 29;7:e7232. doi: 10.7717/peerj.7232. eCollection 2019.PMID: 31392087
Subarachnoid hemorrhage in rats - Visualizing blood distribution in vivo using gadolinium-enhanced magnetic resonance imaging: Technical note.
Simader E, Budinsky L, Helbich TH, Sherif C, Höftberger R, Kasprian G, Raunegger T, Hacker P, Ankersmit HJ, Beer L, Haider T.J Neurosci Methods. 2019 Sep 1;325:108370. doi: 10.1016/j.jneumeth.2019.108370. Epub 2019 Jul 19.PMID: 31326605
Systemic release of heat-shock protein 27 and 70 following severe trauma.
Haider T, Simader E, Glück O, Ankersmit HJ, Heinz T, Hajdu S, Negrin LL.Sci Rep. 2019 Jul 3;9(1):9595. doi: 10.1038/s41598-019-46034-w.PMID: 31270381
Commentary: INSPIRE results? A critical appraisal of study end points.
Hoetzenecker K, Cypel M.J Thorac Cardiovasc Surg. 2019 Oct;158(4):1266-1267. doi: 10.1016/j.jtcvs.2019.06.034. Epub 2019 Jul 2.PMID: 31358332
Apelin inhibition prevents resistance and metastasis associated with anti-angiogenic therapy.
Uribesalgo I, Hoffmann D, Zhang Y, Kavirayani A, Lazovic J, Berta J, Novatchkova M, Pai TP, Wimmer RA, László V, Schramek D, Karim R, Tortola L, Deswal S, Haas L, Zuber J, Szűcs M, Kuba K, Dome B, Cao Y, Haubner BJ, Penninger JM.EMBO Mol Med. 2019 Aug;11(8):e9266. doi: 10.15252/emmm.201809266. Epub 2019 Jun 24.PMID: 31267692
Disconnect between Fibrotic Response and Right Ventricular Dysfunction.
Crnkovic S, Egemnazarov B, Damico R, Marsh LM, Nagy BM, Douschan P, Atsina K, Kolb TM, Mathai SC, Hooper JE, Ghanim B, Klepetko W, Fruhwald F, Lassner D, Olschewski A, Olschewski H, Hassoun PM, Kwapiszewska G.Am J Respir Crit Care Med. 2019 Jun 15;199(12):1550-1560. doi: 10.1164/rccm.201809-1737OC.PMID: 30557518
Targeting TMEM16A to reverse vasoconstriction and remodelling in idiopathic pulmonary arterial hypertension.
Papp R, Nagaraj C, Zabini D, Nagy BM, Lengyel M, Skofic Maurer D, Sharma N, Egemnazarov B, Kovacs G, Kwapiszewska G, Marsh LM, Hrzenjak A, Höfler G, Didiasova M, Wygrecka M, Sievers LK, Szucs P, Enyedi P, Ghanim B, Klepetko W, Olschewski H, Olschewski A.Eur Respir J. 2019 Jun 5;53(6):1800965. doi: 10.1183/13993003.00965-2018. Print 2019 Jun.PMID: 31023847
PD-L1 Expression of Lung Cancer Cells, Unlike Infiltrating Immune Cells, Is Stable and Unaffected by Therapy During Brain Metastasis.
Téglási V, Pipek O, Lózsa R, Berta K, Szüts D, Harkó T, Vadász P, Rojkó L, Döme B, Bagó AG, Tímár J, Moldvay J, Szállási Z, Reiniger L.Clin Lung Cancer. 2019 Sep;20(5):363-369.e2. doi: 10.1016/j.cllc.2019.05.008. Epub 2019 May 15.PMID: 31178388
Interobserver variability impairs radiologic grading of primary graft dysfunction after lung transplantation.
Schwarz S, Muckenhuber M, Benazzo A, Beer L, Gittler F, Prosch H, Röhrich S, Milos R, Schweiger T, Jaksch P, Klepetko W, Hoetzenecker K.J Thorac Cardiovasc Surg. 2019 Sep;158(3):955-962.e1. doi: 10.1016/j.jtcvs.2019.02.134. Epub 2019 May 11.PMID: 31204131
Antibody-Mediated Rejection in a Multiple Lung Transplant Patient: A Case Report.
Radeczky P, Ghimessy ÁK, Farkas A, Csende K, Mészáros L, Török K, Fazekas L, Agócs L, Kocsis Á, Bartók T, Dancs T, Tóth KK, Schönauer N, Bogyó L, Bohács A, Madurka I, Elek J, Döme B, Rényi-Vámos F, Lang G, Gieszer B.Transplant Proc. 2019 May;51(4):1296-1298. doi: 10.1016/j.transproceed.2019.03.005.PMID: 31101218
Donation After Cardiac Death, a Possibility to Expand the Donor Pool: Review and the Hungarian Experience.
Ghimessy ÁK, Farkas A, Gieszer B, Radeczky P, Csende K, Mészáros L, Török K, Fazekas L, Agócs L, Kocsis Á, Bartók T, Dancs T, Tóth KK, Schönauer N, Madurka I, Elek J, Döme B, Rényi-Vámos F, Lang G, Taghavi S, Hötzenecker K, Klepetko W, Bogyó L.Transplant Proc. 2019 May;51(4):1276-1280. doi: 10.1016/j.transproceed.2019.04.003.PMID: 31101213
Lung Transplantation in Hungary From Cardiac Surgeons' Perspective.
Fazekas L, Ghimessy Á, Gieszer B, Radeczky P, Mészáros L, Török K, Bogyó L, Hartyánszky I, Pólos M, Daróczi L, Agócs L, Kocsis Á, Bartók T, Dancs T, Tóth KK, Schönauer N, Madurka I, Elek J, Döme B, Rényi-Vámos F, Lang G, Farkas A.Transplant Proc. 2019 May;51(4):1263-1267. doi: 10.1016/j.transproceed.2019.04.007.PMID: 31101211
Lung Transplant Patients on Kilimanjaro.
Gieszer B, Radeczky P, Farkas A, Csende K, Mészáros L, Török K, Fazekas L, Bogyó L, Agócs L, Kocsis Á, Varga J, Bartók T, Dancs T, Kormosoi Tóth K, Schönauer N, Madurka I, Elek J, Döme B, Rényi-Vámos F, Lang G, Jaksch P, Ghimessy ÁK.Transplant Proc. 2019 May;51(4):1258-1262. doi: 10.1016/j.transproceed.2019.04.004.PMID: 31101210
Impairments in Postural Control and Retest Reliability of Dynamic Posturographic Measures After Lung Transplantation.
Ebenbichler G, Doblhammer S, Pachner M, Habenicht R, Kienbacher T, Mair P, Zemková E, Hirjaková Z, Jaksch P, Klepetko W.Am J Phys Med Rehabil. 2019 May;98(5):353-359. doi: 10.1097/PHM.0000000000001095.PMID: 30422827
Emerging biomarkers in pulmonary metastasectomy.
Lang C, Hoetzenecker K, Schweiger TS. J Vis Surg 2019;5:44 doi: 10.21037/jovs.2019.03.20
Tumor necrosis correlates with PD-L1 and PD-1 expression in lung adenocarcinoma.
Reiniger L, Téglási V, Pipek O, Rojkó L, Glasz T, Vágvölgyi A, Kovalszky I, Gyulai M, Lohinai Z, Rásó E, Tímár J, Döme B, Szállási Z, Moldvay J.Acta Oncol. 2019 Aug;58(8):1087-1094. doi: 10.1080/0284186X.2019.1598575. Epub 2019 Apr 19.PMID: 31002007
Toxicological testing of allogeneic secretome derived from peripheral mononuclear cells (APOSEC): a novel cell-free therapeutic agent in skin disease.
Wuschko S, Gugerell A, Chabicovsky M, Hofbauer H, Laggner M, Erb M, Ostler T, Peterbauer A, Suessner S, Demyanets S, Leuschner J, Moser B, Mildner M, Ankersmit HJ.Sci Rep. 2019 Apr 3;9(1):5598. doi: 10.1038/s41598-019-42057-5.PMID: 30944367
Step by step toward the summit.
Hoetzenecker K.J Thorac Cardiovasc Surg. 2019 Apr;157(4):e219. doi: 10.1016/j.jtcvs.2018.11.001.PMID: 30901810
LRP1 promotes synthetic phenotype of pulmonary artery smooth muscle cells in pulmonary hypertension.
Zucker MM, Wujak L, Gungl A, Didiasova M, Kosanovic D, Petrovic A, Klepetko W, Schermuly RT, Kwapiszewska G, Schaefer L, Wygrecka M.Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1604-1616. doi: 10.1016/j.bbadis.2019.03.012. Epub 2019 Mar 22.PMID: 30910704
Exercise-induced bronchoconstriction, temperature regulation and the role of heat shock proteins in non-asthmatic recreational marathon and half-marathon runners.
Bekos C, Zimmermann M, Unger L, Janik S, Mitterbauer A, Koller M, Fritz R, Gäbler C, Didcock J, Kliman J, Klepetko W, Ankersmit HJ, Moser B.Sci Rep. 2019 Mar 12;9(1):4168. doi: 10.1038/s41598-019-39983-9.PMID: 30862844
Psychometric properties and minimal important differences of SF-36 in Idiopathic Pulmonary Fibrosis.
Witt S, Krauss E, Barbero MAN, Müller V, Bonniaud P, Vancheri C, Wells AU, Vasakova M, Pesci A, Klepetko W, Seeger W, Crestani B, Leidl R, Holle R, Schwarzkopf L, Guenther A.Respir Res. 2019 Mar 1;20(1):47. doi: 10.1186/s12931-019-1010-5.PMID: 30823880
Twenty-year experience with extracorporeal life support as bridge to lung transplantation.
Benazzo A, Schwarz S, Frommlet F, Schweiger T, Jaksch P, Schellongowski P, Staudinger T, Klepetko W, Lang G, Hoetzenecker K; Vienna ECLS Program.J Thorac Cardiovasc Surg. 2019 Jun;157(6):2515-2525.e10. doi: 10.1016/j.jtcvs.2019.02.048. Epub 2019 Feb 27.PMID: 30922636
3D Models in the Diagnosis of Subglottic Airway Stenosis.
Hoetzenecker K, Chan HHL, Frommlet F, Schweiger T, Keshavjee S, Waddell TK, Klepetko W, Irish JC, Yasufuku K.Ann Thorac Surg. 2019 Jun;107(6):1860-1865. doi: 10.1016/j.athoracsur.2019.01.045. Epub 2019 Feb 27.PMID: 30825452
Viral safety of APOSECTM: a novel peripheral blood mononuclear cell derived-biological for regenerative medicine.
Gugerell A, Sorgenfrey D, Laggner M, Raimann J, Peterbauer A, Bormann D, Suessner S, Gabriel C, Moser B, Ostler T, Mildner M, Ankersmit HJ.Blood Transfus. 2020 Jan;18(1):30-39. doi: 10.2450/2019.0249-18. Epub 2019 Feb 21.PMID: 30865581
Getting in shape: Current hurdles in 3-dimensionally printed airway stents.
Schweiger T, Hoetzenecker K.J Thorac Cardiovasc Surg. 2019 May;157(5):e301-e302. doi: 10.1016/j.jtcvs.2019.01.085. Epub 2019 Feb 21.PMID: 30798955
Molecular assessment of rejection and injury in lung transplant biopsies.
Halloran KM, Parkes MD, Chang J, Timofte IL, Snell GI, Westall GP, Hachem R, Kreisel D, Trulock E, Roux A, Juvet S, Keshavjee S, Jaksch P, Klepetko W, Halloran PF.J Heart Lung Transplant. 2019 May;38(5):504-513. doi: 10.1016/j.healun.2019.01.1317. Epub 2019 Feb 6.PMID: 30773443
Solid predominant subtype in lung adenocarcinoma is related to poor prognosis after surgical resection: A systematic review and meta-analysis.
Miyahara N, Nii K, Benazzo A, Hoda MA, Iwasaki A, Klepetko W, Klikovits T, Hoetzenecker K.Eur J Surg Oncol. 2019 Jul;45(7):1156-1162. doi: 10.1016/j.ejso.2019.01.220. Epub 2019 Feb 4.PMID: 30772108
Results of the extended analysis for cancer treatment (EXACT) trial: a prospective translational study evaluating individualized treatment regimens in oncology.
Prager GW, Unseld M, Waneck F, Mader R, Wrba F, Raderer M, Fuereder T, Staber P, Jäger U, Kieler M, Bianconi D, Hoda MA, Baumann L, Reinthaller A, Berger W, Grimm C, Kölbl H, Sibilia M, Müllauer L, Zielinski C.Oncotarget. 2019 Jan 29;10(9):942-952. doi: 10.18632/oncotarget.26604. eCollection 2019 Jan 29.PMID: 30847023
Chronic thromboembolic pulmonary hypertension in Austria and Japan.
Chausheva S, Naito A, Ogawa A, Seidl V, Winter MP, Sharma S, Sadushi-Kolici R, Campean IA, Taghavi S, Moser B, Klepetko W, Ishida K, Matsubara H, Sakao S, Lang IM.J Thorac Cardiovasc Surg. 2019 Aug;158(2):604-614.e2. doi: 10.1016/j.jtcvs.2019.01.019. Epub 2019 Jan 21.PMID: 31084984
Long non-coding RNAs influence the transcriptome in pulmonary arterial hypertension: the role of PAXIP1-AS1.
Jandl K, Thekkekara Puthenparampil H, Marsh LM, Hoffmann J, Wilhelm J, Veith C, Sinn K, Klepetko W, Olschewski H, Olschewski A, Brock M, Kwapiszewska G.J Pathol. 2019 Mar;247(3):357-370. doi: 10.1002/path.5195. Epub 2019 Jan 16.PMID: 30450722
Alemtuzumab induction combined with reduced maintenance immunosuppression is associated with improved outcomes after lung transplantation: A single centre experience.
Benazzo A, Schwarz S, Muckenhuber M, Schweiger T, Muraközy G, Moser B, Sigüenza JM, Lang G, Taghavi S, Klepetko W, Hoetzenecker K, Jaksch P, Lambers C.PLoS One. 2019 Jan 15;14(1):e0210443. doi: 10.1371/journal.pone.0210443. eCollection 2019.PMID: 30645645
Intensive care, right ventricular support and lung transplantation in patients with pulmonary hypertension.
Hoeper MM, Benza RL, Corris P, de Perrot M, Fadel E, Keogh AM, Kühn C, Savale L, Klepetko W.Eur Respir J. 2019 Jan 24;53(1):1801906. doi: 10.1183/13993003.01906-2018. Print 2019 Jan.PMID: 3054597
The FAK inhibitor BI 853520 inhibits spheroid formation and orthotopic tumor growth in malignant pleural mesothelioma.
Laszlo V, Valko Z, Ozsvar J, Kovacs I, Garay T, Hoda MA, Klikovits T, Stockhammer P, Aigner C, Gröger M, Klepetko W, Berger W, Grusch M, Tovari J, Waizenegger IC, Dome B, Hegedus B.J Mol Med (Berl). 2019 Feb;97(2):231-242. doi: 10.1007/s00109-018-1725-7. Epub 2018 Dec 11.PMID: 30539198
Comparison of the antifibrotic effects of the pan-histone deacetylase-inhibitor panobinostat versus the IPF-drug pirfenidone in fibroblasts from patients with idiopathic pulmonary fibrosis.
Korfei M, Stelmaszek D, MacKenzie B, Skwarna S, Chillappagari S, Bach AC, Ruppert C, Saito S, Mahavadi P, Klepetko W, Fink L, Seeger W, Lasky JA, Pullamsetti SS, Krämer OH, Guenther A.PLoS One. 2018 Nov 27;13(11):e0207915. doi: 10.1371/journal.pone.0207915. eCollection 2018.PMID: 30481203
Increased serum concentrations of soluble ST2 predict mortality after burn injury.
Hacker S, Dieplinger B, Werba G, Nickl S, Roth GA, Krenn CG, Mueller T, Ankersmit HJ, Haider T.Clin Chem Lab Med. 2018 Nov 27;56(12):2079-2087. doi: 10.1515/cclm-2018-0042.PMID: 29949506
Subcutaneous treprostinil for the treatment of severe non-operable chronic thromboembolic pulmonary hypertension (CTREPH): a double-blind, phase 3, randomised controlled trial.
Sadushi-Kolici R, Jansa P, Kopec G, Torbicki A, Skoro-Sajer N, Campean IA, Halank M, Simkova I, Karlocai K, Steringer-Mascherbauer R, Samarzija M, Salobir B, Klepetko W, Lindner J, Lang IM.Lancet Respir Med. 2019 Mar;7(3):239-248. doi: 10.1016/S2213-2600(18)30367-9. Epub 2018 Nov 23.PMID: 30477763
New insights into the impact of primary lung adenocarcinoma location on metastatic sites and sequence: A multicenter cohort study.
Klikovits T, Lohinai Z, Fábián K, Gyulai M, Szilasi M, Varga J, Baranya E, Pipek O, Csabai I, Szállási Z, Tímár J, Hoda MA, Laszlo V, Hegedűs B, Renyi-Vamos F, Klepetko W, Ostoros G, Döme B, Moldvay J.Lung Cancer. 2018 Dec;126:139-148. doi: 10.1016/j.lungcan.2018.11.004. Epub 2018 Nov 5.PMID: 30527178
Torque Teno Virus as a Novel Biomarker Targeting the Efficacy of Immunosuppression After Lung Transplantation.
Jaksch P, Kundi M, Görzer I, Muraközy G, Lambers C, Benazzo A, Hoetzenecker K, Klepetko W, Puchhammer-Stöckl E.J Infect Dis. 2018 Nov 5;218(12):1922-1928. doi: 10.1093/infdis/jiy452.PMID: 30053048
Mutational profile of colorectal cancer lung metastases and paired primary tumors by targeted next generation sequencing: implications on clinical outcome after surgery.
Schweiger T, Liebmann-Reindl S, Glueck O, Starlinger P, Laengle J, Birner P, Klepetko W, Pils D, Streubel B, Hoetzenecker K.J Thorac Dis. 2018 Nov;10(11):6147-6157. doi: 10.21037/jtd.2018.10.72.PMID: 30622786
Mechanism of anti-remodelling action of treprostinil in human pulmonary arterial smooth muscle cells.
Lambers C, Kornauth C, Oberndorfer F, Boehm PM, Tamm M, Klepetko W, Roth M.PLoS One. 2018 Nov 1;13(11):e0205195. doi: 10.1371/journal.pone.0205195. eCollection 2018.PMID: 30383775
Transcriptome profiling reveals the complexity of pirfenidone effects in idiopathic pulmonary fibrosis.
Kwapiszewska G, Gungl A, Wilhelm J, Marsh LM, Thekkekara Puthenparampil H, Sinn K, Didiasova M, Klepetko W, Kosanovic D, Schermuly RT, Wujak L, Weiss B, Schaefer L, Schneider M, Kreuter M, Olschewski A, Seeger W, Olschewski H, Wygrecka M.Eur Respir J. 2018 Nov 22;52(5):1800564. doi: 10.1183/13993003.00564-2018. Print 2018 Nov.PMID: 30166321
Cardiac and Pulmonary Cystic Echinococcosis With Massive Obstruction of the Pulmonary Vessel System in a 16-Year-Old Girl.
Kohlmaier B, Trobisch A, Pfurtscheller K, Knez I, Klepetko W, Pilhatsch A, Schweintzger S, Zenz W.Pediatr Infect Dis J. 2018 Nov;37(11):e273-e275. doi: 10.1097/INF.0000000000002066.PMID: 29634619
Chronic Thromboembolic Pulmonary Hypertension and Antiphospholipid Syndrome with Immune Thrombocytopenia: A Case Report.
Skride A, Sablinskis M, Sablinskis K, Lejniece S, Lejnieks A, Klepetko W, Lang IM.Am J Case Rep. 2018 Oct 19;19:1245-1248. doi: 10.12659/AJCR.909778.PMID: 30337514
Myostatin and other musculoskeletal markers in lung transplant recipients.
Kerschan-Schindl K, Ebenbichler G, Gruther W, Föger-Samwald U, Kudlacek S, Patsch J, Gleiss A, Jaksch P, Klepetko W, Pietschmann P.Clin Exp Med. 2019 Feb;19(1):77-85. doi: 10.1007/s10238-018-0532-3. Epub 2018 Oct 13.PMID: 30317402
Docking of Meprin α to Heparan Sulphate Protects the Endothelium from Inflammatory Cell Extravasation.
Biasin V, Wygrecka M, Bärnthaler T, Jandl K, Jain PP, Bálint Z, Kovacs G, Leitinger G, Kolb-Lenz D, Kornmueller K, Peters F, Sinn K, Klepetko W, Heinemann A, Olschewski A, Becker-Pauly C, Kwapiszewska G.Thromb Haemost. 2018 Oct;118(10):1790-1802. doi: 10.1055/s-0038-1670657. Epub 2018 Sep 20.PMID: 30235485
Intraoperative extracorporeal support during lung transplantation in patients bridged with venovenous extracorporeal membrane oxygenation.
Hashimoto K, Hoetzenecker K, Yeung JC, Jeagal L, Donahoe L, Pierre A, de Perrot M, Yasufuku K, Waddell TK, Keshavjee S, Cypel M.J Heart Lung Transplant. 2018 Dec;37(12):1418-1424. doi: 10.1016/j.healun.2018.07.003. Epub 2018 Sep 5.PMID: 30193763
Chronic thromboembolic pulmonary hypertension (CTEPH): Updated Recommendations from the Cologne Consensus Conference 2018.
Wilkens H, Konstantinides S, Lang IM, Bunck AC, Gerges M, Gerhardt F, Grgic A, Grohé C, Guth S, Held M, Hinrichs JB, Hoeper MM, Klepetko W, Kramm T, Krüger U, Lankeit M, Meyer BC, Olsson KM, Schäfers HJ, Schmidt M, Seyfarth HJ, Ulrich S, Wiedenroth CB, Mayer E.Int J Cardiol. 2018 Dec 1;272S:69-78. doi: 10.1016/j.ijcard.2018.08.079. Epub 2018 Aug 28.PMID: 30195840
Patient-specific, 3-dimensionally engineered silicone Y-stents in tracheobronchomalacia: Clinical experience with a novel type of airway stent.
Schweiger T, Gildea TR, Prosch H, Lang G, Klepetko W, Hoetzenecker K.J Thorac Cardiovasc Surg. 2018 Nov;156(5):2019-2021. doi: 10.1016/j.jtcvs.2018.06.049. Epub 2018 Jul 18.PMID: 30104064
Role of (myo)fibroblasts in the development of vascular and connective tissue structure of the C38 colorectal cancer in mice.
Bugyik E, Szabó V, Dezső K, Rókusz A, Szücs A, Nagy P, Tóvári J, László V, Döme B, Paku S.Cancer Commun (Lond). 2018 Jul 5;38(1):46. doi: 10.1186/s40880-018-0316-x.PMID: 29976246
Pre-emptive glottic enlargement before laryngotracheal surgery in patients at high risk for postoperative bilateral vocal fold paralysis.
Schweiger T, Hoetzenecker K, Roesner I, Schneider-Stickler B, Denk-Linnert DM, Klepetko W.Eur J Cardiothorac Surg. 2018 Jul 1;54(1):106-112. doi: 10.1093/ejcts/ezx511.PMID: 29401237
Afatinib restrains K-RAS-driven lung tumorigenesis.
Moll HP, Pranz K, Musteanu M, Grabner B, Hruschka N, Mohrherr J, Aigner P, Stiedl P, Brcic L, Laszlo V, Schramek D, Moriggl R, Eferl R, Moldvay J, Dezso K, Lopez-Casas PP, Stoiber D, Hidalgo M, Penninger J, Sibilia M, Győrffy B, Barbacid M, Dome B, Popper H, Casanova E.Sci Transl Med. 2018 Jun 20;10(446):eaao2301. doi: 10.1126/scitranslmed.aao2301.PMID: 29925635
DNA methylation of microRNA-coding genes in non-small-cell lung cancer patients.
Heller G, Altenberger C, Steiner I, Topakian T, Ziegler B, Tomasich E, Lang G, End-Pfützenreuter A, Zehetmayer S, Döme B, Arns BM, Klepetko W, Zielinski CC, Zöchbauer-Müller S.J Pathol. 2018 Aug;245(4):387-398. doi: 10.1002/path.5079. Epub 2018 Jun 20.PMID: 29570800
The influence of retransplantation on survival for pediatric lung transplant recipients.
Waseda R, Benazzo A, Hoetzenecker K, Jaksch P, Muraközy G, Gruber S, Roth G, Szépfalusi Z, Nachbaur E, Klepetko W.J Thorac Cardiovasc Surg. 2018 Nov;156(5):2025-2034.e2. doi: 10.1016/j.jtcvs.2018.05.080. Epub 2018 Jun 6.PMID: 30343700
Effect of antifibrotics on short-term outcome after bilateral lung transplantation: a multicentre analysis.
Lambers C, Boehm PM, Lee S, Ius F, Jaksch P, Klepetko W, Tudorache I, Ristl R, Welte T, Gottlieb J.Eur Respir J. 2018 Jun 21;51(6):1800503. doi: 10.1183/13993003.00503-2018. Print 2018 Jun.PMID: 29678942
Feasibility and Reliability of Functional Muscle Tests in Lung Transplant Recipients.
Kienbacher T, Achim-Gunacker G, Pachner M, Kerschan-Schindl K, Gunacker P, Habenicht R, Klepetko W, Jaksch P, Doblhammer S, Ebenbichler G.Am J Phys Med Rehabil. 2018 Jun;97(6):390-396. doi: 10.1097/PHM.0000000000000849.PMID: 29016397
Subglottic Resections: How I Teach It.
Hoetzenecker K, Klepetko W.Ann Thorac Surg. 2018 Jul;106(1):1-7. doi: 10.1016/j.athoracsur.2018.05.001. Epub 2018 May 22.PMID: 29792830
Impact of nutritional status on pulmonary function after lung transplantation for cystic fibrosis.
Staufer K, Halilbasic E, Hillebrand P, Harm S, Schwarz S, Jaksch P, Kivaranovic D, Klepetko W, Trauner M, Kazemi-Shirazi L.United European Gastroenterol J. 2018 Aug;6(7):1049-1055. doi: 10.1177/2050640618778381. Epub 2018 May 17.PMID: 30228893
Lung allocation score: the Eurotransplant model versus the revised US model - a cross-sectional study.
Smits JM, Nossent G, Evrard P, Lang G, Knoop C, Kwakkel-van Erp JM, Langer F, Schramm R, van de Graaf E, Vos R, Verleden G, Rondelet B, Hoefer D, Hoek R, Hoetzenecker K, Deuse T, Strelniece A, Green D, de Vries E, Samuel U, Laufer G, Buhl R, Witt C, Gottlieb J.Transpl Int. 2018 Aug;31(8):930-937. doi: 10.1111/tri.13262. Epub 2018 May 11.PMID: 29665090
Pan-RAF and MEK vertical inhibition enhances therapeutic response in non-V600 BRAF mutant cells.
Molnár E, Rittler D, Baranyi M, Grusch M, Berger W, Döme B, Tóvári J, Aigner C, Tímár J, Garay T, Hegedűs B.BMC Cancer. 2018 May 8;18(1):542. doi: 10.1186/s12885-018-4455-x.PMID: 29739364
Nintedanib Is Active in Malignant Pleural Mesothelioma Cell Models and Inhibits Angiogenesis and Tumor Growth In Vivo.
Laszlo V, Valko Z, Kovacs I, Ozsvar J, Hoda MA, Klikovits T, Lakatos D, Czirok A, Garay T, Stiglbauer A, Helbich TH, Gröger M, Tovari J, Klepetko W, Pirker C, Grusch M, Berger W, Hilberg F, Hegedus B, Dome B.Clin Cancer Res. 2018 Aug 1;24(15):3729-3740. doi: 10.1158/1078-0432.CCR-17-1507. Epub 2018 May 3.PMID: 29724868
Controversies in oncology: surgery for small cell lung cancer? It's time to rethink the case.
Hoda MA, Klikovits T, Klepetko W.ESMO Open. 2018 Apr 27;3(3):e000366. doi: 10.1136/esmoopen-2018-000366. eCollection 2018.PMID: 29719730
Usefulness of thrombosis and inflammation biomarkers in chronic thromboembolic pulmonary hypertension-sampling plasma and surgical specimens.
Skoro-Sajer N, Gerges C, Gerges M, Panzenböck A, Jakowitsch J, Kurz A, Taghavi S, Sadushi-Kolici R, Campean I, Klepetko W, Celermajer DS, Lang IM.J Heart Lung Transplant. 2018 Sep;37(9):1067-1074. doi: 10.1016/j.healun.2018.04.003. Epub 2018 Apr 25.PMID: 2980208
Increased serum concentrations of soluble ST2 are associated with pulmonary complications and mortality in polytraumatized patients.
Haider T, Simader E, Hacker P, Ankersmit HJ, Heinz T, Hajdu S, Negrin LL.Clin Chem Lab Med. 2018 Apr 25;56(5):810-817. doi: 10.1515/cclm-2017-0762.PMID: 29341938
Prognostic and diagnostic impact of fibrinogen, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio on thymic epithelial tumors outcome.
Janik S, Raunegger T, Hacker P, Ghanim B, Einwallner E, Müllauer L, Schiefer AI, Moser J, Klepetko W, Ankersmit HJ, Moser B.Oncotarget. 2018 Apr 24;9(31):21861-21875. doi: 10.18632/oncotarget.25076. eCollection 2018 Apr 24.PMID: 29774108
Chemotherapy treatment is associated with altered PD-L1 expression in lung cancer patients.
Rojkó L, Reiniger L, Téglási V, Fábián K, Pipek O, Vágvölgyi A, Agócs L, Fillinger J, Kajdácsi Z, Tímár J, Döme B, Szállási Z, Moldvay J.J Cancer Res Clin Oncol. 2018 Jul;144(7):1219-1226. doi: 10.1007/s00432-018-2642-4. Epub 2018 Apr 19.PMID: 29675791
FGF2 and EGF induce epithelial-mesenchymal transition in malignant pleural mesothelioma cells via a MAPKinase/MMP1 signal.
Schelch K, Wagner C, Hager S, Pirker C, Siess K, Lang E, Lin R, Kirschner MB, Mohr T, Brcic L, Marian B, Holzmann K, Grasl-Kraupp B, Krupitza G, Laszlo V, Klikovits T, Dome B, Hegedus B, Garay T, Reid G, van Zandwijk N, Klepetko W, Berger W, Grusch M, Hoda MA.Carcinogenesis. 2018 Apr 5;39(4):534-545. doi: 10.1093/carcin/bgy018.PMID: 29635378
Low-quality lower lobes-discard, repair, or only use the good rest?
Hoetzenecker K, Klepetko W.J Thorac Cardiovasc Surg. 2018 Jul;156(1):e39-e40. doi: 10.1016/j.jtcvs.2018.03.106. Epub 2018 Apr 3.PMID: 29754795
Reshaping a multimode laser beam into a constructed Gaussian beam for generating a thin light sheet.
Saghafi S, Haghi-Danaloo N, Becker K, Sabdyusheva I, Foroughipour M, Hahn C, Pende M, Wanis M, Bergmann M, Stift J, Hegedus B, Dome B, Dodt HU.J Biophotonics. 2018 Jun;11(6):e201700213. doi: 10.1002/jbio.201700213. Epub 2018 Mar 24.PMID: 29457696
PD-L1 expression is an independent predictor of favorable outcome in patients with localized esophageal adenocarcinoma.
Kollmann D, Ignatova D, Jedamzik J, Chang YT, Jomrich G, Baierl A, Kazakov D, Michal M, French LE, Hoetzenecker W, Schatton T, Asari R, Preusser M, Gnant M, Guenova E, Schoppmann SF.Oncoimmunology. 2018 Mar 13;7(6):e1435226. doi: 10.1080/2162402X.2018.1435226. eCollection 2018.PMID: 29872575
Resident cell lineages are preserved in pulmonary vascular remodeling.
Crnkovic S, Marsh LM, El Agha E, Voswinckel R, Ghanim B, Klepetko W, Stacher-Priehse E, Olschewski H, Bloch W, Bellusci S, Olschewski A, Kwapiszewska G.J Pathol. 2018 Apr;244(4):485-498. doi: 10.1002/path.5044. Epub 2018 Mar 9.PMID: 29359814
Author Correction: Down-regulated GATA-1 up-regulates interferon regulatory factor 3 in lung adenocarcinoma.
Wang LL, Chen ZS, Zhou WD, Shu J, Wang XH, Jin R, Zhuang LL, Hoda MA, Zhang H, Zhou GP.Sci Rep. 2018 Mar 6;8(1):4299. doi: 10.1038/s41598-018-22517-0.PMID: 29511303
ISHLT Consensus Statement on adult and pediatric airway complications after lung transplantation: Definitions, grading system, and therapeutics.
Crespo MM, McCarthy DP, Hopkins PM, Clark SC, Budev M, Bermudez CA, Benden C, Eghtesady P, Lease ED, Leard L, D'Cunha J, Wigfield CH, Cypel M, Diamond JM, Yun JJ, Yarmus L, Machuzak M, Klepetko W, Verleden G, Hoetzenecker K, Dellgren G, Mulligan M.J Heart Lung Transplant. 2018 May;37(5):548-563. doi: 10.1016/j.healun.2018.01.1309. Epub 2018 Feb 7.PMID: 29550149
Chylothorax in a 32-Year-Old Patient With Lymphangioleiomyomatosis After Bilateral Lung Transplant.
Boehm PM, Ghanim BD, Matilla J, Klepetko W, Taghavi S.Ann Thorac Surg. 2018 Jun;105(6):e263-e264. doi: 10.1016/j.athoracsur.2017.12.042. Epub 2018 Feb 2.PMID: 29408242
Malignant pleural mesothelioma-the impact of globalization on rare diseases.
Hoda MA, Ploenes T, Aigner C.J Thorac Dis. 2018 Feb;10(2):638-640. doi: 10.21037/jtd.2017.12.139.PMID: 29607128
Treprostinil inhibits proliferation and extracellular matrix deposition by fibroblasts through cAMP activation.
Lambers C, Roth M, Jaksch P, Muraközy G, Tamm M, Klepetko W, Ghanim B, Zhao F.Sci Rep. 2018 Jan 18;8(1):1087. doi: 10.1038/s41598-018-19294-1.PMID: 29348469
The inflammatory cell landscape in the lungs of patients with idiopathic pulmonary arterial hypertension.
Marsh LM, Jandl K, Grünig G, Foris V, Bashir M, Ghanim B, Klepetko W, Olschewski H, Olschewski A, Kwapiszewska G.Eur Respir J. 2018 Jan 25;51(1):1701214. doi: 10.1183/13993003.01214-2017. Print 2018 Jan.PMID: 29371380
Progressive Stenosis of Both Main Bronchi Associated With Recurrent Infections of a Carinal Pouch.
Schweiger T, Hoetzenecker K, Prosch H, Hackl M, Oszvath B, Lang G, Klepetko W.Ann Thorac Surg. 2018 Jan;105(1):e1-e3. doi: 10.1016/j.athoracsur.2017.07.037.PMID: 29233352
Lung transplantation for idiopathic pulmonary arterial hypertension on intraoperative and postoperatively prolonged extracorporeal membrane oxygenation provides optimally controlled reperfusion and excellent outcome.
Moser B, Jaksch P, Taghavi S, Muraközy G, Lang G, Hager H, Krenn C, Roth G, Faybik P, Bacher A, Aigner C, Matilla JR, Hoetzenecker K, Hacker P, Lang I, Klepetko W.Eur J Cardiothorac Surg. 2018 Jan 1;53(1):178-185. doi: 10.1093/ejcts/ezx212.PMID: 2895032
Intraoperative extracorporeal membrane oxygenation and the possibility of postoperative prolongation improve survival in bilateral lung transplantation.
Hoetzenecker K, Schwarz S, Muckenhuber M, Benazzo A, Frommlet F, Schweiger T, Bata O, Jaksch P, Ahmadi N, Muraközy G, Prosch H, Hager H, Roth G, Lang G, Taghavi S, Klepetko W.J Thorac Cardiovasc Surg. 2018 May;155(5):2193-2206.e3. doi: 10.1016/j.jtcvs.2017.10.144. Epub 2017 Dec 7.PMID: 29653665
Extracorporeal life support as a bridge to lung transplantation-experience of a high-volume transplant center.
Hoetzenecker K, Donahoe L, Yeung JC, Azad S, Fan E, Ferguson ND, Del Sorbo L, de Perrot M, Pierre A, Yasufuku K, Singer L, Waddell TK, Keshavjee S, Cypel M.J Thorac Cardiovasc Surg. 2018 Mar;155(3):1316-1328.e1. doi: 10.1016/j.jtcvs.2017.09.161. Epub 2017 Nov 22.PMID: 29248282
Advanced pulmonary arterial hypertension: mechanical support and lung transplantation.
Bartolome S, Hoeper MM, Klepetko W.Eur Respir Rev. 2017 Dec 20;26(146):170089. doi: 10.1183/16000617.0089-2017. Print 2017 Dec 31.PMID: 29263172
Intraoperative extracorporeal membrane oxygenation and the possibility of postoperative prolongation improve survival in bilateral lung transplantation.
Hoetzenecker K, Schwarz S, Muckenhuber M, Benazzo A, Frommlet F, Schweiger T, Bata O, Jaksch P, Ahmadi N, Muraközy G, Prosch H, Hager H, Roth G, Lang G, Taghavi S, Klepetko W.J Thorac Cardiovasc Surg. 2018 May;155(5):2193-2206.e3. doi: 10.1016/j.jtcvs.2017.10.144. Epub 2017 Dec 7.PMID: 29653665
Mediastinal staging by videomediastinoscopy in clinical N1 non-small cell lung cancer: a prospective multicentre study.
Decaluwé H, Dooms C, D'Journo XB, Call S, Sanchez D, Haager B, Beelen R, Kara V, Klikovits T, Aigner C, Tournoy K, Zahin M, Moons J, Brioude G, Trujillo JC, Klepetko W, Turna A, Passlick B, Molins L, Rami-Porta R, Thomas P, Leyn P.Eur Respir J. 2017 Dec 21;50(6):1701493. doi: 10.1183/13993003.01493-2017. Print 2017 Dec.PMID: 29269579
Circulating complement component 4d (C4d) correlates with tumor volume, chemotherapeutic response and survival in patients with malignant pleural mesothelioma.
Klikovits T, Stockhammer P, Laszlo V, Dong Y, Hoda MA, Ghanim B, Opitz I, Frauenfelder T, Nguyen-Kim TDL, Weder W, Berger W, Grusch M, Aigner C, Klepetko W, Dome B, Renyi-Vamos F, Oehler R, Hegedus B.Sci Rep. 2017 Nov 28;7(1):16456. doi: 10.1038/s41598-017-16551-7.PMID: 29184132
Is it really dumb to leave a stump?
Hoetzenecker K, Klepetko W.J Thorac Cardiovasc Surg. 2018 Jul;156(1):461-462. doi: 10.1016/j.jtcvs.2017.11.064. Epub 2017 Nov 22.PMID: 29305030
Extracorporeal life support as a bridge to lung transplantation-experience of a high-volume transplant center.
Hoetzenecker K, Donahoe L, Yeung JC, Azad S, Fan E, Ferguson ND, Del Sorbo L, de Perrot M, Pierre A, Yasufuku K, Singer L, Waddell TK, Keshavjee S, Cypel M.J Thorac Cardiovasc Surg. 2018 Mar;155(3):1316-1328.e1. doi: 10.1016/j.jtcvs.2017.09.161. Epub 2017 Nov 22.PMID: 29248282
Intrathoracic solitary fibrous tumor - an international multicenter study on clinical outcome and novel circulating biomarkers.
Ghanim B, Hess S, Bertoglio P, Celik A, Bas A, Oberndorfer F, Melfi F, Mussi A, Klepetko W, Pirker C, Berger W, Harmati I, Farkas A, Jan Ankersmit H, Dome B, Fillinger J, Aigner C, Hegedus B, Renyi-Vamos F, Lang G.Sci Rep. 2017 Oct 2;7(1):12557. doi: 10.1038/s41598-017-12914-2.PMID: 28970578
Awake minimal invasive carinal resection-tightrope walking in thoracic surgery?
Schweiger T, Klepetko W, Hoetzenecker K.J Thorac Dis. 2017 Oct;9(10):3667-3669. doi: 10.21037/jtd.2017.09.31.PMID: 29268370
When meat allergy meets cardiac surgery: A driver for humanized bioprosthesis.
Ankersmit HJ, Copic D, Simader E.J Thorac Cardiovasc Surg. 2017 Oct;154(4):1326-1327. doi: 10.1016/j.jtcvs.2017.05.041.PMID: 28918922
Treatment of primary graft dysfunction after lung transplantation with orally inhaled AP301: A prospective, randomized pilot study.
Aigner C, Slama A, Barta M, Mitterbauer A, Lang G, Taghavi S, Matilla J, Ullrich R, Krenn K, Jaksch P, Markstaller K, Klepetko W.J Heart Lung Transplant. 2017 Sep 30:S1053-2498(17)32036-3. doi: 10.1016/j.healun.2017.09.021. Online ahead of print.PMID: 29055604
Surgery for T4 lung cancer invading the thoracic aorta: Do we push the limits?
Marulli G, Rendina EA, Klepetko W, Perkmann R, Zampieri D, Maurizi G, Klikovits T, Zaraca F, Venuta F, Perissinotto E, Rea F.J Surg Oncol. 2017 Dec;116(8):1141-1149. doi: 10.1002/jso.24784. Epub 2017 Sep 18.PMID: 28922454
Urgent Lung Transplantation in Severe Acute Respiratory Failure Based on Rapidly Progressive Interstitial Lung Disease: A Case Report.
Madurka I, Elek J, Schönauer N, Bartók T, Kormosói-Tóth K, Zöllei É, Ghimessy Á, Lang G, Klepetko W, Rényi-Vámos F.Transplant Proc. 2017 Sep;49(7):1544-1548. doi: 10.1016/j.transproceed.2017.06.020.PMID: 28838437
Early Postoperative Problems After Lung Transplantation: First-Year Experiences in Light of the Newly Established National Hungarian Lung Transplantation Program.
Madurka I, Elek J, Schönauer N, Bartók T, Kormosói-Tóth K, Radeczky P, Gieszer B, Ghimessy Á, Lang G, Klepetko W, Rényi-Vámos F.Transplant Proc. 2017 Sep;49(7):1538-1543. doi: 10.1016/j.transproceed.2017.06.018.PMID: 28838436
Launching the Hungarian Lung Transplantation Program.
Rényi-Vámos F, Radeczky P, Gieszer B, Ghimessy Á, Czebe K, Török K, Döme B, Elek J, Klepetko W, Lang G, Madurka I.Transplant Proc. 2017 Sep;49(7):1535-1537. doi: 10.1016/j.transproceed.2017.06.017.PMID: 28838435
Heat shock protein 27 acts as a predictor of prognosis in chronic heart failure patients.
Traxler D, Lainscak M, Simader E, Ankersmit HJ, Jug B.Clin Chim Acta. 2017 Oct;473:127-132. doi: 10.1016/j.cca.2017.08.028. Epub 2017 Aug 24.PMID: 28844461
Renal Impairment Hampers Bisphosphonate Treatment in a Quarter of Lung Cancer Patients with Bone Metastasis.
Fábián K, Puskás R, Kakuk T, Prés L, Fejes D, Szegedi Z, Rojkó L, Szállási Z, Döme B, Pipek O, Moldvay J.Basic Clin Pharmacol Toxicol. 2018 Jan;122(1):126-132. doi: 10.1111/bcpt.12854. Epub 2017 Aug 24.PMID: 28730730
PD1-positive tumor-infiltrating lymphocytes are associated with poor clinical outcome after pulmonary metastasectomy for colorectal cancer.
Kollmann D, Schweiger T, Schwarz S, Ignatova D, Chang YT, Lewik G, Schoppmann SF, Hoetzenecker W, Klepetko W, Guenova E, Hoetzenecker K.Oncoimmunology. 2017 Aug 18;6(9):e1331194. doi: 10.1080/2162402X.2017.1331194. eCollection 2017.PMID: 28932634
Take a deep breath and everything will be all right….
Hoetzenecker K, Klepetko W.J Thorac Cardiovasc Surg. 2017 Dec;154(6):2152. doi: 10.1016/j.jtcvs.2017.08.008. Epub 2017 Aug 17.PMID: 28916219
BARD1 serum autoantibodies for the detection of lung cancer.
Pilyugin M, Descloux P, André PA, Laszlo V, Dome B, Hegedus B, Sardy S, Janes S, Bianco A, Laurent GJ, Irminger-Finger I.PLoS One. 2017 Aug 7;12(8):e0182356. doi: 10.1371/journal.pone.0182356. eCollection 2017.PMID: 28786985
Surgical therapy of thymic tumours with pleural involvement: an ESTS Thymic Working Group Project.
Moser B, Fadel E, Fabre D, Keshavjee S, de Perrot M, Thomas P, Brioude G, Van Raemdonck D, Viskens S, Lang-Lazdunski L, Bille A, Weder W, Jungraithmayr W, Ruffini E, Guerrera F, Gómez de Antonio D, Liberman M, Novoa N, Scarci M, Janik S, Klepetko W.Eur J Cardiothorac Surg. 2017 Aug 1;52(2):346-355. doi: 10.1093/ejcts/ezx090.PMID: 28449028
Evaluating the significance of density, localization, and PD-1/PD-L1 immunopositivity of mononuclear cells in the clinical course of lung adenocarcinoma patients with brain metastasis.
Téglási V, Reiniger L, Fábián K, Pipek O, Csala I, Bagó AG, Várallyai P, Vízkeleti L, Rojkó L, Tímár J, Döme B, Szállási Z, Swanton C, Moldvay J.Neuro Oncol. 2017 Aug 1;19(8):1058-1067. doi: 10.1093/neuonc/now309.PMID: 28201746
Image-Based Chemical Structure Determination.
Ofner J, Brenner F, Wieland K, Eitenberger E, Kirschner J, Eisenmenger-Sittner C, Török S, Döme B, Konegger T, Kasper-Giebl A, Hutter H, Friedbacher G, Lendl B, Lohninger H.Sci Rep. 2017 Jul 28;7(1):6832. doi: 10.1038/s41598-017-07041-x.PMID: 28754996
Safety and tolerability of topically administered autologous, apoptotic PBMC secretome (APOSEC) in dermal wounds: a randomized Phase 1 trial (MARSYAS I).
Simader E, Traxler D, Kasiri MM, Hofbauer H, Wolzt M, Glogner C, Storka A, Mildner M, Gouya G, Geusau A, Fuchs C, Eder C, Graf A, Schaden M, Golabi B, Aretin MB, Suessner S, Gabriel C, Klepetko W, Tschachler E, Ankersmit HJ.Sci Rep. 2017 Jul 24;7(1):6216. doi: 10.1038/s41598-017-06223-x.PMID: 28740204
Elevated CRP levels predict poor outcome and tumor recurrence in patients with thymic epithelial tumors: A pro- and retrospective analysis.
Janik S, Bekos C, Hacker P, Raunegger T, Ghanim B, Einwallner E, Beer L, Klepetko W, Müllauer L, Ankersmit HJ, Moser B.Oncotarget. 2017 Jul 18;8(29):47090-47102. doi: 10.18632/oncotarget.17478.PMID: 28514756
Importance of kynurenine in pulmonary hypertension.
Nagy BM, Nagaraj C, Meinitzer A, Sharma N, Papp R, Foris V, Ghanim B, Kwapiszewska G, Kovacs G, Klepetko W, Pieber TR, Mangge H, Olschewski H, Olschewski A.Am J Physiol Lung Cell Mol Physiol. 2017 Nov 1;313(5):L741-L751. doi: 10.1152/ajplung.00517.2016. Epub 2017 Jul 13.PMID: 28705908
Extracorporeal support in airway surgery.
Hoetzenecker K, Klepetko W, Keshavjee S, Cypel M.J Thorac Dis. 2017 Jul;9(7):2108-2117. doi: 10.21037/jtd.2017.06.17.PMID: 28840012
Hypoxic vascular response and ventilation/perfusion matching in end-stage COPD may depend on p22phox.
Nagaraj C, Tabeling C, Nagy BM, Jain PP, Marsh LM, Papp R, Pienn M, Witzenrath M, Ghanim B, Klepetko W, Weir EK, Heschl S, Kwapiszewska G, Olschewski A, Olschewski H.Eur Respir J. 2017 Jul 20;50(1):1601651. doi: 10.1183/13993003.01651-2016. Print 2017 Jul.PMID: 28729471
Selective lobar exclusion by venous clamping during ex vivo lung perfusion.
Schweiger T, Benazzo A, Lang G, Matilla JR, Klepetko W.J Thorac Cardiovasc Surg. 2017 Nov;154(5):e87-e89. doi: 10.1016/j.jtcvs.2017.06.018. Epub 2017 Jun 15.PMID: 28870398
Intrinsic remote conditioning of the myocardium as a comprehensive cardiac response to ischemia and reperfusion.
Pavo N, Lukovic D, Zlabinger K, Lorant D, Goliasch G, Winkler J, Pils D, Auer K, Ankersmit HJ, Giricz Z, Sárközy M, Jakab A, Garamvölgyi R, Emmert MY, Hoerstrup SP, Hausenloy DJ, Ferdinandy P, Maurer G, Gyöngyösi M.Oncotarget. 2017 Jun 12;8(40):67227-67240. doi: 10.18632/oncotarget.18438. eCollection 2017 Sep 15.PMID: 28978029
Pediatric airway surgery.
Hoetzenecker K, Schweiger T, Denk-Linnert DM, Klepetko W.J Thorac Dis. 2017 Jun;9(6):1663-1671. doi: 10.21037/jtd.2017.05.50.PMID: 28740684
Immunosuppression after lung transplantation: the search for the holy grail continues.
Schwarz S, Jaksch P, Klepetko W, Hoetzenecker K.J Thorac Dis. 2017 Jun;9(6):1412-1414. doi: 10.21037/jtd.2017.04.66.PMID: 28740645
Down-regulated GATA-1 up-regulates interferon regulatory factor 3 in lung adenocarcinoma.
Wang LL, Chen ZS, Zhou WD, Shu J, Wang XH, Jin R, Zhuang LL, Hoda MA, Zhang H, Zhou GP.Sci Rep. 2017 May 31;7(1):2551. doi: 10.1038/s41598-017-02700-5.PMID: 28566697
Analysis of region specific gene expression patterns in the heart and systemic responses after experimental myocardial ischemia.
Zimmermann M, Beer L, Ullrich R, Lukovic D, Simader E, Traxler D, Wagner T, Nemec L, Altenburger L, Zuckermann A, Gyöngyösi M, Ankersmit HJ, Mildner M.Oncotarget. 2017 May 17;8(37):60809-60825. doi: 10.18632/oncotarget.17955. eCollection 2017 Sep 22.PMID: 28977827
Thymic minimally invasive surgery: state of the art across the world-Europe.
Matilla JR, Klepetko W, Moser B.J Vis Surg. 2017 May 16;3:70. doi: 10.21037/jovs.2017.04.01. eCollection 2017.PMID: 29078633
Expression of Programmed Cell Death Protein 1 by Tumor-Infiltrating Lymphocytes and Tumor Cells is Associated with Advanced Tumor Stage in Patients with Esophageal Adenocarcinoma.
Kollmann D, Ignatova D, Jedamzik J, Chang YT, Jomrich G, Paireder M, Kristo I, Kazakov D, Michal M, Cozzio A, Hoetzenecker W, Schatton T, Asari R, Preusser M, Guenova E, Schoppmann SF.Ann Surg Oncol. 2017 Sep;24(9):2698-2706. doi: 10.1245/s10434-017-5858-7. Epub 2017 Apr 20.PMID: 28429196
Trimodality therapy for Pancoast tumors: T4 is not a contraindication to radical surgery.
Waseda R, Klikovits T, Hoda MA, Hoetzenecker K, Bertoglio P, Dieckmann K, Zöchbauer-Müller S, Pirker R, Prosch H, Döme B, Klepetko W.J Surg Oncol. 2017 Aug;116(2):227-235. doi: 10.1002/jso.24629. Epub 2017 Apr 13.PMID: 28407246
Cell secretome based drug substances in regenerative medicine: when regulatory affairs meet basic science.
Beer L, Mildner M, Ankersmit HJ.Ann Transl Med. 2017 Apr;5(7):170. doi: 10.21037/atm.2017.03.50.PMID: 28480206
Increased trefoil factor 2 levels in patients with chronic kidney disease.
Lebherz-Eichinger D, Tudor B, Ankersmit HJ, Reiter T, Haas M, Einwallner E, Roth-Walter F, Krenn CG, Roth GA.PLoS One. 2017 Mar 29;12(3):e0174551. doi: 10.1371/journal.pone.0174551. eCollection 2017.PMID: 28355260
Impact of cyclooxygenase-2 and prostaglandin-E2 expression on clinical outcome after pulmonary metastasectomy.
Lang C, Hrdliczka E, Schweiger T, Glueck O, Lewik G, Schwarz S, Benazzo A, Lang G, Klepetko W, Hoetzenecker K.J Thorac Dis. 2017 Mar;9(3):621-635. doi: 10.21037/jtd.2017.02.83.PMID: 28449470
Ionizing radiation regulates long non-coding RNAs in human peripheral blood mononuclear cells.
Beer L, Nemec L, Wagner T, Ristl R, Altenburger LM, Ankersmit HJ, Mildner M.J Radiat Res. 2017 Mar 1;58(2):201-209. doi: 10.1093/jrr/rrw111.PMID: 27974506
Standard donor lung procurement with normothermic ex vivo lung perfusion: A prospective randomized clinical trial.
Slama A, Schillab L, Barta M, Benedek A, Mitterbauer A, Hoetzenecker K, Taghavi S, Lang G, Matilla J, Ankersmit H, Hager H, Roth G, Klepetko W, Aigner C.J Heart Lung Transplant. 2017 Jul;36(7):744-753. doi: 10.1016/j.healun.2017.02.011. Epub 2017 Feb 20.PMID: 28314503
Amplified canonical transforming growth factor-β signalling via heat shock protein 90 in pulmonary fibrosis.
Sibinska Z, Tian X, Korfei M, Kojonazarov B, Kolb JS, Klepetko W, Kosanovic D, Wygrecka M, Ghofrani HA, Weissmann N, Grimminger F, Seeger W, Guenther A, Schermuly RT.Eur Respir J. 2017 Feb 23;49(2):1501941. doi: 10.1183/13993003.01941-2015. Print 2017 Feb.PMID: 28182573
Re: Excellent outcome of donor lobectomy with various surgical techniques for the interlobar artery.
Klepetko W.Eur J Cardiothorac Surg. 2017 Feb 1;51(2):283-284. doi: 10.1093/ejcts/ezw320.PMID: 28007873
The Lymphatic Phenotype of Lung Allografts in Patients With Bronchiolitis Obliterans Syndrome and Restrictive Allograft Syndrome.
Traxler D, Schweiger T, Schwarz S, Schuster MM, Jaksch P, Lang G, Birner P, Klepetko W, Ankersmit HJ, Hoetzenecker K.Transplantation. 2017 Feb;101(2):310-315. doi: 10.1097/TP.0000000000001263.PMID: 27163544
The evidence for and against different modes of tumour cell extravasation in the lung: diapedesis, capillary destruction, necroptosis, and endothelialization.
Paku S, Laszlo V, Dezso K, Nagy P, Hoda MA, Klepetko W, Renyi-Vamos F, Timar J, Reynolds AR, Dome B.J Pathol. 2017 Mar;241(4):441-447. doi: 10.1002/path.4855. Epub 2017 Jan 27.PMID: 28026875
SPAG6 and L1TD1 are transcriptionally regulated by DNA methylation in non-small cell lung cancers.
Altenberger C, Heller G, Ziegler B, Tomasich E, Marhold M, Topakian T, Müllauer L, Heffeter P, Lang G, End-Pfützenreuter A, Döme B, Arns BM, Klepetko W, Zielinski CC, Zöchbauer-Müller S.Mol Cancer. 2017 Jan 5;16(1):1. doi: 10.1186/s12943-016-0568-5.PMID: 28093071
KRAS-mutation incidence and prognostic value are metastatic site-specific in lung adenocarcinoma: poor prognosis in patients with KRAS mutation and bone metastasis.
Lohinai Z, Klikovits T, Moldvay J, Ostoros G, Raso E, Timar J, Fabian K, Kovalszky I, Kenessey I, Aigner C, Renyi-Vamos F, Klepetko W, Dome B, Hegedus B.Sci Rep. 2017 Jan 4;7:39721. doi: 10.1038/srep39721.PMID: 28051122
Inhibition of the transcriptional repressor complex Bcl-6/BCoR induces endothelial sprouting but does not promote tumor growth.
Buchberger E, Payrhuber D, El Harchi M, Zagrapan B, Scheuba K, Zommer A, Bugyik E, Dome B, Kral JB, Schrottmaier WC, Schabbauer G, Petzelbauer P, Gröger M, Bilban M, Brostjan C.Oncotarget. 2017 Jan 3;8(1):552-564. doi: 10.18632/oncotarget.13477.PMID: 27880939
Lung Abscess: An Early Complication of Lung Transplantation in a Patient with Cystic Fibrosis.
Markelić I, Jakopović M, Klepetko W, Džubur F, Hećimović A, Makek MJ, Samaržija M, Dugac AV.Int J Organ Transplant Med. 2017;8(4):213-216. Epub 2017 Nov 1.PMID: 29321838
Limited Tumor Tissue Drug Penetration Contributes to Primary Resistance against Angiogenesis Inhibitors.
Torok S, Rezeli M, Kelemen O, Vegvari A, Watanabe K, Sugihara Y, Tisza A, Marton T, Kovacs I, Tovari J, Laszlo V, Helbich TH, Hegedus B, Klikovits T, Hoda MA, Klepetko W, Paku S, Marko-Varga G, Dome B.Theranostics. 2017 Jan 1;7(2):400-412. doi: 10.7150/thno.16767. eCollection 2017.PMID: 28042343
An association of particulate air pollution and traffic exposure with mortality after lung transplantation in Europe.
Ruttens D, Verleden SE, Bijnens EM, Winckelmans E, Gottlieb J, Warnecke G, Meloni F, Morosini M, Van Der Bij W, Verschuuren EA, Sommerwerck U, Weinreich G, Kamler M, Roman A, Gomez-Olles S, Berastegui C, Benden C, Holm AM, Iversen M, Schultz HH, Luijk B, Oudijk EJ, Kwakkel-van Erp JM, Jaksch P, Klepetko W, Kneidinger N, Neurohr C, Corris P, Fisher AJ, Lordan J, Meachery G, Piloni D, Vandermeulen E, Bellon H, Hoffmann B, Vienneau D, Hoek G, de Hoogh K, Nemery B, Verleden GM, Vos R, Nawrot TS, Vanaudenaerde BM.Eur Respir J. 2017 Jan 18;49(1):1600484. doi: 10.1183/13993003.00484-2016. Print 2017 Jan.PMID: 27836956
Intrapulmonary Human Cytomegalovirus Replication in Lung Transplant Recipients Is Associated With a Rise of CCL-18 and CCL-20 Chemokine Levels.
Weseslindtner L, Görzer I, Roedl K, Küng E, Jaksch P, Klepetko W, Puchhammer-Stöckl E.Transplantation. 2017 Jan;101(1):197-203. doi: 10.1097/TP.0000000000001065.PMID: 26910332
Vessel co-option is common in human lung metastases and mediates resistance to anti-angiogenic therapy in preclinical lung metastasis models.
Bridgeman VL, Vermeulen PB, Foo S, Bilecz A, Daley F, Kostaras E, Nathan MR, Wan E, Frentzas S, Schweiger T, Hegedus B, Hoetzenecker K, Renyi-Vamos F, Kuczynski EA, Vasudev NS, Larkin J, Gore M, Dvorak HF, Paku S, Kerbel RS, Dome B, Reynolds AR.J Pathol. 2017 Feb;241(3):362-374. doi: 10.1002/path.4845. Epub 2016 Dec 29.PMID: 27859259
A comparison of sample preparation strategies for biological tissues and subsequent trace element analysis using LA-ICP-MS.
Bonta M, Török S, Hegedus B, Döme B, Limbeck A.Anal Bioanal Chem. 2017 Mar;409(7):1805-1814. doi: 10.1007/s00216-016-0124-6. Epub 2016 Dec 14.PMID: 27966170
The plasma membrane Ca2+ pump PMCA4b inhibits the migratory and metastatic activity of BRAF mutant melanoma cells.
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