Forschungsschwerpunkte

Ausgewählte Publikationen

Kleinzelliges Lungenkarzinom (SCLC) 

• In-depth proteomic analysis reveals unique subtype-specific signatures in human small-cell lung cancer

• Expression patterns and prognostic relevance of subtype-specific transcription factors in surgically resected small-cell lung cancer: an international multicenter study

• Lymphocyte-to-monocyte ratio is an independent prognostic factor in surgically treated small cell lung cancer: An international multicenter analysis

• Clinical relevance of circulating activin A and follistatin in small cell lung cancer

• Molecular profiles of small cell lung cancer subtypes: therapeutic implications

• Next-Generation Sequencing May Discriminate Extreme Long-term versus Short-term Survival in Patients with Metastatic Small Cell Lung Cancer (SCLC)

Nicht-kleinzelliges Lungenkarzinom (NSCLC)

• Bone-Specific Metastasis Pattern of Advanced-Stage Lung Adenocarcinoma According to the Localization of the Primary Tumor

• Current therapy of KRAS-mutant lung cancer

• New insights into the impact of primary lung adenocarcinoma location on metastatic sites and sequence: A multicenter cohort study

Malignes Pleuramesotheliom (MPM)

• Prognostic impact of PD-1 and PD-L1 expression in malignant pleural mesothelioma: an international multicenter study

• Telomerase Reverse Transcriptase Promoter Mutations Identify a Genomically Defined and Highly Aggressive Human Pleural Mesothelioma Subgroup

• Nintedanib Is Active in Malignant Pleural Mesothelioma Cell Models and Inhibits Angiogenesis and Tumor Growth In Vivo

• Fibroblast growth factor receptor inhibition is active against mesothelioma and synergizes with radio- and chemotherapy

• Dysregulated Expression of the MicroRNA miR-137 and Its Target YBX1 Contribute to the Invasive Characteristics of Malignant Pleural Mesothelioma

Pulmonale Metastasen (PM)

• Vessel co-option is common in human lung metastases and mediates resistance to anti-angiogenic therapy in preclinical lung metastasis models